ID  A1L4K1;
PN  Fibronectin type III and SPRY domain-containing protein 2;
GN  FSD2;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Nucleus {ECO:0000250|UniProtKB:H0UZ81}. Sarcoplasmic reticulum {ECO:0000250|UniProtKB:H0UZ81}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:H0UZ81}. Note=In skeletal muscles and striated muscles flanks Z-disks. Partially colocalizes with RYR2 in the sarcoplasmic reticulum. {ECO:0000250|UniProtKB:H0UZ81}.
DR  UNIPROT: A1L4K1;
DR  UNIPROT: B3KVG1;
DR  UNIPROT: B7ZM02;
DR  Pfam: PF00041;
DR  Pfam: PF00622;
DR  PROSITE: PS50188;
DR  PROSITE: PS50853;
DR  DisGeNET: 123722;
DE  Function: 
DE  Reference Proteome: Yes;
DE  Interaction: Q14324; IntAct: EBI-5661041; Score: 0.00
DE  Interaction: Q7Z3I7; IntAct: EBI-10172604; Score: 0.60
DE  Interaction: Q7Z3B3; IntAct: EBI-10178303; Score: 0.56
DE  Interaction: O95990; IntAct: EBI-10192906; Score: 0.56
DE  Interaction: P10768; IntAct: EBI-10197227; Score: 0.78
DE  Interaction: P17024; IntAct: EBI-10199416; Score: 0.56
DE  Interaction: P28070; IntAct: EBI-10204607; Score: 0.56
DE  Interaction: P29972; IntAct: EBI-10204944; Score: 0.56
DE  Interaction: P31146; IntAct: EBI-10205786; Score: 0.78
DE  Interaction: Q00994; IntAct: EBI-10222282; Score: 0.72
DE  Interaction: Q06787; IntAct: EBI-10224474; Score: 0.56
DE  Interaction: Q08117; IntAct: EBI-10224779; Score: 0.67
DE  Interaction: Q14738; IntAct: EBI-10233892; Score: 0.56
DE  Interaction: Q15973; IntAct: EBI-10237322; Score: 0.56
DE  Interaction: Q16670; IntAct: EBI-10238175; Score: 0.56
DE  Interaction: Q3B820; IntAct: EBI-10240125; Score: 0.56
DE  Interaction: Q53FD0; IntAct: EBI-10242267; Score: 0.56
DE  Interaction: Q5JS98; IntAct: EBI-10244397; Score: 0.56
DE  Interaction: Q6NYC8; IntAct: EBI-10251682; Score: 0.72
DE  Interaction: Q6P1J9; IntAct: EBI-10252260; Score: 0.78
DE  Interaction: Q6PJG3; IntAct: EBI-10253974; Score: 0.56
DE  Interaction: Q86VK4; IntAct: EBI-10259792; Score: 0.56
DE  Interaction: Q86YD7; IntAct: EBI-10260722; Score: 0.72
DE  Interaction: Q8IY31; IntAct: EBI-10262646; Score: 0.56
DE  Interaction: Q8N381; IntAct: EBI-10265171; Score: 0.56
DE  Interaction: Q8N8B7; IntAct: EBI-10267719; Score: 0.56
DE  Interaction: Q8NEF3; IntAct: EBI-10270620; Score: 0.56
DE  Interaction: Q8TAU3; IntAct: EBI-10272085; Score: 0.72
DE  Interaction: Q8TD31; IntAct: EBI-10274456; Score: 0.72
DE  Interaction: Q96BZ8; IntAct: EBI-10282596; Score: 0.72
DE  Interaction: Q96NC0; IntAct: EBI-10291592; Score: 0.56
DE  Interaction: Q96SQ5; IntAct: EBI-10293466; Score: 0.72
DE  Interaction: Q9BXY8; IntAct: EBI-10301478; Score: 0.56
DE  Interaction: Q9H0A9; IntAct: EBI-10304145; Score: 0.60
DE  Interaction: Q9H0E9; IntAct: EBI-10304359; Score: 0.72
DE  Interaction: Q9H6F0; IntAct: EBI-10307479; Score: 0.56
DE  Interaction: Q9H788; IntAct: EBI-10308323; Score: 0.72
DE  Interaction: Q9HC52; IntAct: EBI-10310314; Score: 0.72
DE  Interaction: Q9P0T4; IntAct: EBI-10317754; Score: 0.72
DE  Interaction: Q9UGP5; IntAct: EBI-10320763; Score: 0.60
DE  Interaction: Q9UIE0; IntAct: EBI-10321904; Score: 0.56
DE  Interaction: Q9Y3B7; IntAct: EBI-10327384; Score: 0.72
DE  Interaction: Q8IXW7; IntAct: EBI-21249370; Score: 0.37
DE  Interaction: Q99608; IntAct: EBI-21251010; Score: 0.37
DE  Interaction: Q9H0I2; IntAct: EBI-24276119; Score: 0.56
DE  Interaction: Q8TBB1; IntAct: EBI-24292204; Score: 0.56
DE  Interaction: Q9P1Y5; IntAct: EBI-24292226; Score: 0.56
DE  Interaction: Q9H9D4; IntAct: EBI-24302090; Score: 0.56
DE  Interaction: Q5T619; IntAct: EBI-24309981; Score: 0.56
DE  Interaction: Q96EG3; IntAct: EBI-24311294; Score: 0.56
DE  Interaction: Q96AL5; IntAct: EBI-24314166; Score: 0.56
DE  Interaction: Q8IVT4; IntAct: EBI-24315626; Score: 0.56
DE  Interaction: Q6NX45; IntAct: EBI-24321517; Score: 0.56
DE  Interaction: Q9BT49; IntAct: EBI-24325694; Score: 0.56
DE  Interaction: Q9BWG6; IntAct: EBI-24340348; Score: 0.56
DE  Interaction: Q96HB5; IntAct: EBI-24349830; Score: 0.56
DE  Interaction: Q9UK33; IntAct: EBI-24352123; Score: 0.56
DE  Interaction: P78358; IntAct: EBI-24352383; Score: 0.56
DE  Interaction: Q96EZ8; IntAct: EBI-24352759; Score: 0.56
DE  Interaction: Q8WWY3; IntAct: EBI-24355284; Score: 0.56
DE  Interaction: O76064; IntAct: EBI-24355797; Score: 0.56
DE  Interaction: Q9ULM2; IntAct: EBI-24362843; Score: 0.56
DE  Interaction: Q96HP4; IntAct: EBI-25253734; Score: 0.56
DE  Interaction: O43602; IntAct: EBI-25254540; Score: 0.56
DE  Interaction: P0CB47; IntAct: EBI-25255462; Score: 0.56
DE  Interaction: P56524; IntAct: EBI-25255284; Score: 0.56
DE  Interaction: Q3SY00; IntAct: EBI-25255985; Score: 0.56
DE  Interaction: O60645; IntAct: EBI-25258050; Score: 0.56
DE  Interaction: Q9P2K3; IntAct: EBI-24366860; Score: 0.56
DE  Interaction: P13682; IntAct: EBI-24478087; Score: 0.56
DE  Interaction: Q07002; IntAct: EBI-24478674; Score: 0.56
DE  Interaction: Q969G3; IntAct: EBI-24492471; Score: 0.56
DE  Interaction: O95295; IntAct: EBI-24500672; Score: 0.56
DE  Interaction: Q2TBE0; IntAct: EBI-24508217; Score: 0.56
DE  Interaction: O14964; IntAct: EBI-24370108; Score: 0.56
DE  Interaction: Q8TAB5; IntAct: EBI-24382819; Score: 0.56
DE  Interaction: O43482; IntAct: EBI-24385225; Score: 0.56
DE  Interaction: Q14119; IntAct: EBI-24388342; Score: 0.56
DE  Interaction: Q2TBA0; IntAct: EBI-24398616; Score: 0.56
DE  Interaction: Q99633; IntAct: EBI-24401399; Score: 0.56
DE  Interaction: Q5W5X9; IntAct: EBI-25260730; Score: 0.56
DE  Interaction: Q9ULD5; IntAct: EBI-24422254; Score: 0.56
DE  Interaction: Q6ZNE5; IntAct: EBI-24423012; Score: 0.56
DE  Interaction: Q9Y2P0; IntAct: EBI-24424287; Score: 0.56
DE  Interaction: O60941; IntAct: EBI-24426448; Score: 0.56
DE  Interaction: O95363; IntAct: EBI-24427910; Score: 0.56
DE  Interaction: Q96PV4; IntAct: EBI-24432894; Score: 0.56
DE  Interaction: Q9BQ89; IntAct: EBI-24438032; Score: 0.56
DE  Interaction: P36508; IntAct: EBI-24445889; Score: 0.56
DE  Interaction: P53365; IntAct: EBI-24447892; Score: 0.56
DE  Interaction: Q8IYE0; IntAct: EBI-24463350; Score: 0.56
DE  Interaction: Q9UJV3; IntAct: EBI-24468925; Score: 0.56
DE  Interaction: Q9Y247; IntAct: EBI-24470709; Score: 0.56
DE  Interaction: P46013; IntAct: EBI-20562326; Score: 0.35
DE  Interaction: Q9Y394; IntAct: EBI-20903160; Score: 0.40
DE  Interaction: P40426; IntAct: EBI-22133174; Score: 0.37
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0016529;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MEEESGEELGLDRSTPKDFHFYHMDLYDSEDRLHLFPEENTRMRKVVQAEMANESRGAGDGKAQRDLQEEVDELVHLYGL
SQ  EDDHELGDEFVDENIPRTGVSEYPPYMMKRRDPAREQRDWRLSGEAAEAEDLGFGGWGSAGQCQDLREAYRYTHGRASEE
SQ  YECYVIPEEEDEEEAADVFCVTCKTPIRAFQKVFDEHKEHEVIPLNEALESAKDEIHKNMYKLEKQIIEMENFANHLEEV
SQ  FITVEENFGKQEQNFESHYNEILETLAQKYEEKIQALGEKKKEKLEALYGQLVSCGENLDTCKELMETIEEMCHEEKVDF
SQ  IKDAVAMADRLGKFLKTKTDVEISAQPEFEDQTLDFSDVEQLMGSINTIPAPSAPVINPQVPNSATGSSVRVCWSLYSDD
SQ  TVESYQLSYRPVQDSSPGTDQAEFTVTVKETYCSVTNLVPNTQYEFWVTAHNRAGPSPSSERAVYMTAPSPPIIKTKEIR
SQ  SCEEAVLICWESGNLNPVDSYTVELTQAESPEASGVTESVVGIPTCESVVQLQPGRSYIIYVRALNMGGPSVRSEPATVH
SQ  TIGSYFRLNKDTCHPWLTISEDGLTAVRSERRTPARELSPSDTHFTRCVAVMGNLIPVRGHHYWEVEVDEHLDYRVGVAF
SQ  ADVRKQEDLGANCLSWCMRHTFASSRHKYEFLHNRTTPDIRITVPPKKIGILLDYEHSKLSFFNVDLSQHLYTFSCQLHE
SQ  FVHPCFSLEKPGCLKVHNGISMPKHVTFY
//