ID  A1YFX9;
PN  Oxidoreductase HTATIP2;
GN  HTATIP2;
OS  9597;
SL  Nucleus Position: SL-0178;
SL  Comments: Cytoplasm {ECO:0000250}. Nucleus envelope {ECO:0000250}.
DR  UNIPROT: A1YFX9;
DR  Pfam: PF13460;
DE  Function: Oxidoreductase required for tumor suppression. NADPH-bound form inhibits nuclear import by competing with nuclear import substrates for binding to a subset of nuclear transport receptors. May act as a redox sensor linked to transcription through regulation of nuclear import (By similarity). {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0005635;
GO  GO:0051287;
GO  GO:0016620;
GO  GO:0001525;
GO  GO:0006915;
GO  GO:0030154;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAETEALSKLREDFRMQNKSVFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQEVVDFEKLDDYAS
SQ  AFQGHDVGFCCLGTTRGKAGAEGFARVDRDYVLKSAELAKAGGCKHFNLLSSKGADKSSNFLYLQVKGEVEAKVEELKFD
SQ  RYSVFRPGVXLCDRQESRPGEWLVRKFFGSLPDSWASGHSVPVVTVVRAMLNNVVRPRDKQMELLENKAIHDLGKAHGSL
SQ  KP
//