ID  A5A6S6;
PN  Trimeric intracellular cation channel type A;
GN  TMEM38A;
OS  9986;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Sarcoplasmic reticulum membrane {ECO:0000269|PubMed:17611541}; Multi-pass membrane protein {ECO:0000269|PubMed:17611541}. Nucleus membrane {ECO:0000269|PubMed:17611541}.
DR  UNIPROT: A5A6S6;
DR  Pfam: PF05197;
DE  Function: Monovalent cation channel required for maintenance of rapid intracellular calcium release. May act as a potassium counter-ion channel that functions in synchronization with calcium release from intracellular stores. {ECO:0000250|UniProtKB:Q3TMP8, ECO:0000269|PubMed:17611541}.
DE  Reference Proteome: Yes;
DE  Interaction: A5A6S6; IntAct: EBI-15646438; Score: 0.52
GO  GO:0016021;
GO  GO:0031965;
GO  GO:0033017;
GO  GO:0042802;
GO  GO:0005267;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MELLSALSLGELALSFSRVPLFPVFDLSYFIVSILYLKYEPGAVELSRRHPVASWLCAMLHCFGSYILADLLLGEPLIDY
SQ  FSNNSSILLASAVWYLIFFCPLDLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKGSGVA
SQ  LLSNVEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFIFTMFMVSCKVFLTATHSHSSPFDVL
SQ  EAYVCPVLFGTGSGGDHPQDNHGAWPGGPPSGALATKSKEELSEGSRKKKTKKAD
//