ID  A8XV40;
PN  Probable spastin homolog spas-1;
GN  spas;
OS  6238;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Localized to the perinuclear region of the cytoplasm in early embryos. Present in the cytoskeletal fraction. {ECO:0000250}.
DR  UNIPROT: A8XV40;
DR  Pfam: PF00004;
DR  Pfam: PF17862;
DR  PROSITE: PS00674;
DE  Function: Severs microtubules, probably in an ATP-dependent fashion. {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0005874;
GO  GO:0015630;
GO  GO:0048471;
GO  GO:0005524;
GO  GO:0016887;
GO  GO:0016853;
GO  GO:0008568;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MFAFSKAPAGCSTYERVTQKFQDGSNKLRAAIEMDELTKQNGTINEKLQTAELYKQARQMLKEANEFNIMDIPESKRSEV
SQ  REKREKTLNLEKSAQDRLIKICNEVDPNMKRASTAADPCRAARITPRNTRATVPGDKKVSKVKQTEKAPHVCSRGDRCGA
SQ  HQPPPEKKSTPLKPVNQIRTRVKENKNPIGVQQQVFSFILSCCMRRNCRRPHYLFPCMISLKMNYFKFQATLPNQLNTVN
SQ  RSNLLKGVDKAIGERLLDEILDSTGVRMDDVAGCHSAKATLEEAVILPALNPNLFSGLRQPVKGILLFGPPGNGKTLLAK
SQ  AVAGESKQMFFNISASSLTSKWVGDSEKTIRGLFQIARNGQPSIIFIDEIDSILCERSEKDAEVSRRMKTEFLVQFDGAT
SQ  SSPDDRILVIGATNRPYELDDAVLRRFPKRIMLNLPDTEARKELITNTLKKHDMMDGLSSSDIRYIASNTSGFSNSDLVA
SQ  LCKEAAMVPVREIHRSKLSVTDGDKIRKIRASDFDTALRTIRPSTSDRILSKLSDFSRNFGC
//