ID  B4JHB4;
PN  Protein asunder;
GN  asun;
OS  7222;
SL  Nucleus Position: SL-0198;
SL  Comments: Nucleus {ECO:0000250|UniProtKB:Q9VEX5}. Cytoplasm {ECO:0000250|UniProtKB:Q9VEX5}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q9VEX5}. Note=Colocalizes with dynein-dynactin on the nuclear surface at the meiotic G2/prophase transition in primary spermatocytes. Nuclear location is required for recruitment of dynein motors to nuclear envelope at G2/M. {ECO:0000250|UniProtKB:Q9VEX5}.
DR  UNIPROT: B4JHB4;
DR  Pfam: PF10221;
DE  Function: Plays a role as a regulator of spermatogenesis. Crucial regulator of the mitotic cell cycle and development. Required for the correct dynein-dynactin perinuclear localization important for nucleus- centrosome coupling that occur upon meiotic progression of primary spermatocytes. Crucial regulator of the mitotic cell cycle and development. Plays a role in sperm motility and fertility. May have a role in the PNG/PLU/GNU pathway (By similarity). {ECO:0000250|UniProtKB:Q9VEX5}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0032039;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0051301;
GO  GO:0051642;
GO  GO:0046843;
GO  GO:0030317;
GO  GO:0051321;
GO  GO:0051663;
GO  GO:0060814;
GO  GO:0080154;
GO  GO:0007346;
GO  GO:0034472;
GO  GO:0007283;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MFERNEKTIFVLDHTRYFSISSEQYISMDYLKGKPMPAETPAAGSSVGTQLSKSLWTCAVESSIEYCRIVWDLFPGRKHV
SQ  RFIVSDTAAHIVNTWSPSTQNMSHVSNAMMMVSVPSRSIPQSSDYSVIHGLRAAIEALAEPTDEQLQAAQVGCKKISNEG
SQ  RVICITSARDNTSMKSLEDIFNTVLLQQNALVGPPGKKGLSIDHCHLVILNIVPLGVESLVTNRSLLEISPLLDVEIHTV
SQ  HAPNISDKLLHLIMGHYDLASTTVTNIPMKEEQNANSSANYDVEILHARAAHTKVCGPDFTLTTSIKPGTSYETVTLKWC
SQ  TPRGCGSSDLQPCVGQYNVTPVDVTSRPSSCLINFLLNGRSVLLEVPRKTGTKTTSHMLSARGGEIFVHSLSIARSAMDE
SQ  APSITDGPGGRVADYRIPELGQLLKMSRMVPLKAKPKGKMSQGEHLWRRLPRYFPRTMNVTILFNLQRQLSWLPHFLHLL
SQ  VKEDMDKQDEVRCQQQIHELYKSASRGDMLPFTNTNNTRPKMSKTKDQYRLFYRELEQLIQLNVQTVHHKNLLESLQSLR
SQ  AAYGDVTNKSEPGAAHLRSYTESPLSPERLEPNSTSSSSNSLLKASKRRMSSSGQRSLLDMISSAERSQSSKRLDFTGRL
SQ  CTPIGQTAKLYPDFGNKDKDILTPGVIPSNLKDDSIRS
//