ID  D3ZZ07;
PN  Cathepsin 7;
GN  Cts7;
OS  10116;
SL  Nucleus Position: SL-0198;
SL  Comments: Endosome {ECO:0000250|UniProtKB:Q91ZF2}. Lysosome {ECO:0000250|UniProtKB:Q91ZF2}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q91ZF2}. Golgi apparatus {ECO:0000250|UniProtKB:Q91ZF2}. Nucleus {ECO:0000250|UniProtKB:Q91ZF2}. Secreted, extracellular space {ECO:0000250|UniProtKB:Q91ZF2}.
DR  UNIPROT: D3ZZ07;
DR  Pfam: PF08246;
DR  Pfam: PF00112;
DR  PROSITE: PS00139;
DR  PROSITE: PS00639;
DE  Function: Involved in trophoblast cell proliferation and differentiation probably by affecting mitotic cell cycle progression. Proteolytic activity and nuclear localization are essential for its role in cell cycle progression (By similarity). {ECO:0000250|UniProtKB:Q91ZF2}.
DE  Reference Proteome: Yes;
GO  GO:0005768;
GO  GO:0005615;
GO  GO:0005794;
GO  GO:0005764;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0004197;
GO  GO:0051301;
GO  GO:0006955;
GO  GO:0000278;
GO  GO:0045930;
GO  GO:0051603;
GO  GO:0060707;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MTVAVFLAILCLRAALAAPRPDYSLDAEWEEWKRNNAKTYSPEEEKQRRAVWEENVKMIKWHTMQNGLWMNNFTIEMNEF
SQ  GDMTGEEMRMMTDSSALTLRNGKHIQKRNVKIPKTLDWRDTGCVAPVRSQGGCGACWAFSVAASIESQLFKKTGKLIPLS
SQ  VQNLIDCTVTYGNNDCSGGKPYTAFQYVKNNGGLEAEATYPYEAKLRHCRYRPERSVVKIARFFVVPRNEEALMQALVTY
SQ  GPIAVAIDGSHASFKRYRGGIYHEPKCRRDTLDHGLLLVGYGYEGHESENRKYWLLKNSHGEQWGERGYMKLPRDQNNYC
SQ  GIASYAMYPLL
//