ID  E7FDB3;
PN  Nanos homolog 1;
GN  nanos1;
OS  7955;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:11691838}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:11691838}.
DR  UNIPROT: E7FDB3;
DR  Pfam: PF05741;
DR  PROSITE: PS51522;
DE  Function: Acts as a translational repressor. Can mediate repression affecting different steps in the translation process: cap-driven, IRES- driven, polyadenylated RNAs or nonpolyadenylated RNAs (By similarity). Essential for the development of primordial germ cells (PGCs) by ensuring their proper migration and survival. {ECO:0000250, ECO:0000269|PubMed:11691838}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0060293;
GO  GO:0048471;
GO  GO:0003729;
GO  GO:0030371;
GO  GO:0008270;
GO  GO:0007281;
GO  GO:0008354;
GO  GO:0017148;
GO  GO:0048477;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MDFLNHNYLSARASYDYTFNFWNDYLGLSTLVTKNSKHSVPQNPNSITESLKATLGLDDSPPCPCVMGEGDSGGHLDSCC
SQ  CPPPASISILDLKERFSILSPFQNQNQGSLLSSSQEREIGIGGGFAGFDLFGVERKMRKPAARNKQEPKICVFCRNNGAP
SQ  EEVYGSHVLKTPDGRVVCPILRAYTCPLCSANGDNAHTIKYCPLSKDQPAQRVLKGGRAVGGKRVKIF
//