ID  F4ICX9;
PN  TSK-associating protein 1;
GN  TSA1;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Comments: Endoplasmic reticulum lumen. Nucleus envelope {ECO:0000269|PubMed:15964904, ECO:0000269|PubMed:24348487}. Cytoplasm {ECO:0000269|PubMed:15964904, ECO:0000269|PubMed:24348487}. Note=In interphase, found in ER bodies and at the nuclear envelope (PubMed:24348487). During mitosis, concentrates in limited areas close to the ends of spindle microtubules ahead of separating chromatids (PubMed:15964904). {ECO:0000269|PubMed:15964904, ECO:0000269|PubMed:24348487}.
DR  UNIPROT: F4ICX9;
DR  UNIPROT: F4ICY0;
DR  UNIPROT: Q94AE1;
DR  UNIPROT: Q9C831;
DE  Function: Involved in seedling development in the dark. May be involved, when interacting with TSK, in the organization of spindle microtubules and may participate, when interacting with GIP1, in structural links between the nuclear envelope and the cytoskeleton. {ECO:0000269|PubMed:22133685, ECO:0000269|PubMed:24348487}.
DE  Reference Proteome: Yes;
DE  Interaction: Q9AT76; IntAct: EBI-16074844; Score: 0.37
GO  GO:0009535;
GO  GO:0005788;
GO  GO:0005635;
GO  GO:0005777;
GO  GO:0000325;
GO  GO:0099503;
GO  GO:0005509;
GO  GO:0050832;
GO  GO:0009640;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MEIYTMKTNFLVLALSLCILLSSFHEVSCQDDGSGLSNLDLIERDYQDSVNALQGKDDEDQSAKIQSENQNNTTVTDKNT
SQ  ISLSLSDESEVGSVSDESVGRSSLLDQIKLEFEAHHNSINQAGSDGVKAESKDDDEELSAHRQKMLEEIEHEFEAASDSL
SQ  KQLKTDDVNEGNDEEHSAKRQSLLEEIEREFEAATKELEQLKVNDFTGDKDDEEHSAKRKSMLEAIEREFEAAMEGIEAL
SQ  KVSDSTGSGDDEEQSAKRLSMLEEIEREFEAASKGLEQLRASDSTADNNEEEHAAKGQSLLEEIEREFEAATESLKQLQV
SQ  DDSTEDKEHFTAAKRQSLLEEIEREFEAATKDLKQLNDFTEGSADDEQSAKRNKMLEDIEREFEAATIGLEQLKANDFSE
SQ  GNNNEEQSAKRKSMLEEIEREFEAAIGGLKQIKVDDSRNLEEESAKRKIILEEMEREFEEAHSGINAKADKEESAKKQSG
SQ  SAIPEVLGLGQSGGCSCSKQDEDSSIVIPTKYSIEDILSEESAVQGTETSSLTASLTQLVENHRKEKESLLGHRVLTSPS
SQ  IASSTSESSATSETVETLRAKLNELRGLTARELVTRKDFGQILITAASFEELSSAPISYISRLAKYRNVIKEGLEASERV
SQ  HIAQVRAKMLKEVATEKQTAVDTHFATAKKLAQEGDALFVKIFAIKKLLAKLEAEKESVDGKFKETVKELSHLLADASEA
SQ  YEEYHGAVRKAKDEQAAEEFAKEATQSAEIIWVKFLSSL
//