ID  F4IZR5;
PN  Protein EXPORTIN 1B;
GN  XPO1B;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:Q9TVM2}. Nucleus membrane {ECO:0000250|UniProtKB:Q9TVM2}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9TVM2}; Nucleoplasmic side {ECO:0000250|UniProtKB:Q9TVM2}.
DR  UNIPROT: F4IZR5;
DR  UNIPROT: Q0WV73;
DR  UNIPROT: Q94IV0;
DR  UNIPROT: Q94KD5;
DR  UNIPROT: Q9M9N0;
DR  Pfam: PF08767;
DR  Pfam: PF18777;
DR  Pfam: PF18784;
DR  Pfam: PF18787;
DR  Pfam: PF03810;
DR  Pfam: PF08389;
DR  PROSITE: PS50166;
DE  Function: Receptor for the leucine-rich nuclear export signal (NES). Binds cooperatively to the NES on its target protein and to the small GTPase Ran in its active GTP-bound form (By similarity). Required for the maternal-to-embryonic transition and during gametophyte development (PubMed:18791220). {ECO:0000250|UniProtKB:Q9SMV6, ECO:0000269|PubMed:18791220}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0005634;
GO  GO:0009506;
GO  GO:0005049;
GO  GO:0031267;
GO  GO:0009553;
GO  GO:0051028;
GO  GO:0009555;
GO  GO:0009846;
GO  GO:0009860;
GO  GO:0006611;
GO  GO:0000055;
GO  GO:0000056;
TP  Membrane Topology: Peripheral; Source: UniProt - By Similarity {ECO:0000250|UniProtKB:Q9TVM2};
SQ  MAAEKLRDLSQPIDVVLLDATVEAFYSTGSKEERASADNILRDLKANPDTWLQVVHILQNTSSTHTKFFALQVLEGVIKY
SQ  RWNALPVEQRDGMKNYISDVIVQLSRDEASFRTERLYVNKLNIILVQIVKQEWPAKWKSFIPDLVIAAKTSETICENCMA
SQ  ILKLLSEEVFDFSKGEMTQQKIKELKQSLNSEFQLIHELCLYVLSASQRQELIRATLSALHAYLSWIPLGYIFESPLLEI
SQ  LLKFFPVPAYRNLTLQCLSEVASLNFGDFYDMQYVKMYSIFMNQLQAILPLNLNIPEAYSTGSSEEQAFIQNLALFFTSF
SQ  FKLHIKILESAPENISLLLAGLGYLISISYVDDTEVFKVCLDYWNSLVLELFGTRHHACHPALTPSLFGLQMAFLPSTVD
SQ  GVKSEVTERQKLYSDPMSKLRGLMISRTAKPEEVLIVEDENGNIVRETMKDNDVLVQYKIMRETLIYLSHLDHEDTEKQM
SQ  LSKLSKQLSGEEWAWNNLNTLCWAIGSISGSMVVEQENRFLVMVIRDLLSLCEVVKGKDNKAVIASNIMYVVGQYSRFLR
SQ  AHWKFLKTVVHKLFEFMHETHPGVQDMACDTFLKIVQKCKRKFVIVQVGESEPFVSELLSGLATIVGDLQPHQIHTFYES
SQ  VGSMIQAESDPQKRGEYLQRLMALPNQKWAEIIGQARQSADILKEPDVIRTVLNILQTNTRVATSLGTFFLSQISLIFLD
SQ  MLNVYRMYSELVSSSIANGGPYASRTSLVKLLRSVKREILKLIETFLDKAENQPHIGKQFVPPMMDQVLGDYARNVPDAR
SQ  ESEVLSLFATIINKYKVVMRDEVPLIFEAVFQCTLEMITKNFEDYPEHRLKFFSLLRAIATFCFRALIQLSSEQLKLVMD
SQ  SVIWAFRHTERNIAETGLNLLLEMLKNFQKSDFCNKFYQTYFLQIEQEVFAVLTDTFHKPGFKLHVLVLQHLFSLVESGS
SQ  LAEPLWDAATVPHPYSNNVAFVLEYTTKLLSSSFPNMTTTEVTQFVNGLYESRNDVGRFKDNIRDFLIQSKEFSAQDNKD
SQ  LYAEEAAAQMERERQRMLSIPGLIAPSEIQDDMADS
//