ID  G0SDQ4;
PN  Nucleoporin NUP85;
GN  NUP85;
OS  759272;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000250|UniProtKB:P46673}. Nucleus membrane {ECO:0000250|UniProtKB:P46673}; Peripheral membrane protein {ECO:0000250|UniProtKB:P46673}; Cytoplasmic side {ECO:0000250|UniProtKB:P46673}. Nucleus membrane {ECO:0000250|UniProtKB:P46673}; Peripheral membrane protein {ECO:0000250|UniProtKB:P46673}; Nucleoplasmic side {ECO:0000250|UniProtKB:P46673}. Note=Symmetric distribution. {ECO:0000250|UniProtKB:P46673}.
DR  UNIPROT: G0SDQ4;
DR  UNIPROT: G0ZGU8;
DR  Pfam: PF07575;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP85 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization. {ECO:0000250|UniProtKB:P46673}.
DE  Reference Proteome: Yes;
DE  Interaction: G0S0E7; IntAct: EBI-16069336; Score: 0.62
DE  Interaction: G0S2G1; IntAct: EBI-16069488; Score: 0.62
DE  Interaction: G0S2X1; IntAct: EBI-16069488; Score: 0.35
DE  Interaction: G0S9A7; IntAct: EBI-16069651; Score: 0.35
DE  Interaction: G0SA60; IntAct: EBI-16069846; Score: 0.35
DE  Interaction: G0SAK3; IntAct: EBI-16069488; Score: 0.52
DE  Interaction: G0SER9; IntAct: EBI-16069651; Score: 0.35
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0051028;
GO  GO:0015031;
TP  Membrane Topology: Peripheral; Source: UniProt - By Similarity {ECO:0000250|UniProtKB:P46673};
SQ  MFRVPDDSILSSSPAPSTPDKSRRAGSSNLFRDSTASSAASTTPAGTPPVKFLGSSIMRPSDKNASSSVDDDQPAVGLFT
SQ  GIGGGVGVGMGAGTGATAAAKAAKKNLFAAVSGERRRNVPLGRSGRGHDSRQPSRLRKSIGVDDLEDEEEEEEKKKKPQL
SQ  LKPKGKVQEKKKDEPVRGLFTGTSLAPPPLSKAAAAATTTTTTGPTKSFGLTYEEFGESEEEDSGLTGGQDAEGELDDSM
SQ  WLERSPERPAIGDESDLLLMATPAATERVRREAEDIFRATAMGAGATTRRHEYRYASLAKDVYTQLGTAPLVEPPQLILS
SQ  TEALLEQLYDEGVGTHDDDARLDETLAAVAVQLINLWQDHVDAIAQPEEDGHVADIGPGPRASPFEKAYWLATLALQLHH
SQ  TRALDGGVEPLPATLFQWLNDRHDMYAGQVEEILRYRPSPACHSLFWQAVFMSLLRGRVKDATQLLRRAGWEHVRRGGQQ
SQ  RGEYAYSDRALENVLRVVDETVSVLESCPGYDGNWEIWSSEWTLFRVRAQGALEHLRRFAEGKDTSFGDSLFGSSTGSNR
SQ  GYTGYRDHTLAGLARRAESQVPWDVYESLNVVFDIVLGQQASILEAAQDWLEATIGLFGWWDERNNNNNNNNNNNNNNNG
SQ  YQKPGRTQALVLHSSPAHHINNDSESYLDRLARAFHAAVASDFHFNSQNPVEIGMACIFEDNIKGVIGLLRSWSLPIAAA
SQ  VAQVASLGRWLPPHRPKGMYALEDLDMDDLEVLGVDPGAPDEVDGVKDSTLVQYAQALVEYEGLETVRDRAGVYREGWEL
SQ  AISVLGRMDSPERSEEMVRDIVEHLVQGLTVDSTETVDRLWTMLNELSMITYAEEMTETFGDILARESHRYGEAMWYYAL
SQ  AHRPNKVREVMNLLISYSLIQSTAFPPAADLDDYLHRLLSDRKHTLEQYAKQDMEAAELLGKMLSGYAALRQFYDIRDNV
SQ  DATSISPVSRRQQAAAALISVIASSDDNIRGGLVDQTRDGIVSEDFLLALLGEALVFVSNPDNTFVHHGHAAVPILSQDQ
SQ  IDVLLKAVEDLTAVSERVYNVCDEFLQLVLASAPGGALKGSKPADLLKKGQDGQQMVLAGSSLIASQLQKSLLGGSGSAL
SQ  GKVPVKRGWDWREGMPAKMKGEDVIRRLRLGLAKDLARLWLAEADALVW
//