ID  O14188;
PN  Ras GTPase-activating-like protein rng2;
GN  rng2;
OS  284812;
SL  Nucleus Position: SL-0178;
SL  Comments: Cytoplasm, cytoskeleton. Nucleus envelope. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Note=Localized to the F-actin ring and spindle pole body during interphase and mitosis. Also found in septum.
DR  UNIPROT: O14188;
DR  UNIPROT: Q9USG0;
DR  PDB: 1P2X;
DR  PDB: 1P5S;
DR  Pfam: PF00307;
DR  Pfam: PF00612;
DR  Pfam: PF00616;
DR  Pfam: PF03836;
DR  PROSITE: PS50021;
DR  PROSITE: PS50096;
DR  PROSITE: PS50018;
DE  Function: Required for cytokinesis. Component of the contractile F- actin ring; required for its construction following assembly of F-actin at the division site. {ECO:0000269|PubMed:9635188}.
DE  Reference Proteome: Yes;
DE  Interaction: P05933; IntAct: EBI-1152509; Score: 0.52
DE  Interaction: P10989; IntAct: EBI-7190604; Score: 0.49
GO  GO:0005737;
GO  GO:0071341;
GO  GO:0110085;
GO  GO:0120104;
GO  GO:0044732;
GO  GO:0005635;
GO  GO:0005816;
GO  GO:0051015;
GO  GO:0005516;
GO  GO:0008093;
GO  GO:0005096;
GO  GO:1903478;
GO  GO:0000917;
GO  GO:1903486;
GO  GO:1903475;
GO  GO:1903479;
GO  GO:1902404;
GO  GO:1902406;
GO  GO:0032956;
GO  GO:0043087;
GO  GO:0007165;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MDVNVGLSRLQSQAGAPVGTKGSNTRLAAKQRETLQAYDYLCRVDEAKKWIEECLGTDLGPTSTFEQSLRNGVVLALLVQ
SQ  KFQPDKLIKIFYSNELQFRHSDNINKFLDFIHGIGLPEIFHFELTDIYEGKNLPKVIYCIHALSYFLSMQDLAPPLIKSD
SQ  ENLSFTDEDVSIIVRRLRQSNVILPNFKALSADFMLRASPVSSRTPSPTRFPKHARFQTLNSSDSASIYSSPYTSPTLEF
SQ  SKKDASARSDILKMHRRTKSATPSLEQFNEPYKQTLPSHSIEFEDSFFQPPSQKGHMQRSFLTTFSAPTRRREALFSTTS
SQ  GLSQRSPVDEKIVNAIQACGRGVLVRLRLVDMLQSLVEQSSSVVLLQAVIRGYISRNTYRIRKKAYDELVNWVTSIQSIS
SQ  RAYLIRAQYRKVVLQEEATKSIQTLQSIIRGGFYRRKYHSLIERLDLFTPSFVLIQSSALGFLTRHAIVNMLDNLYNYIP
SQ  LFNRMQSILRANMFRNEWSNFLDSVQSFPVSFHSICKGRLIRDSINRLNGSLLGELDNFIKLQNLSRGFMIRRAFKEKLE
SQ  KLKASTSSFIALQAIVRAFLLRKNLESIYDSFQKSHLSVIKAQSLYRGFITRTKIDYCNDYLLKRLPDIVFMQSAVRAIL
SQ  LRDDVNYTEVQLDSFIPEIVLLQSLIRGYLSRNKFSRKLQNFHKNMENPIVAKSIFRGRQEGLAYRELATAKNPPVMTVK
SQ  NFVHLLDDTNFDFEEEVLLEKMRKEIVQQVRDNEEIEVHINELDVKIALLVKNKISLDDVLKHHNKYKFGKQSTEYLKIN
SQ  TLSMKSLNNSSRKFLELYQCFFYVLQTNEMYLANYFQALKTEGTSSVKIRHAVYLVLQIFGHGSNRREEVLLLRFISQVI
SQ  KLEAALVNSSQDLLSDDCVWKLLFTGYRGDVREVKLWKTILGRIHKVLVADNHLDFEINPLTLFKSFNPEVASQTDSPKL
SQ  TLSLAMQHPPTRNLYVSRLRELRKLCQSFLVALSKNIENIPYALCYTAAQLKNSLQRYFPAAHKEEIFGVIGKFVYWAYV
SQ  APVLVSPDNFKLVDGSITALQRKNLYTLSSILSEIFSIESCDSKQLGFFRPLSEFIEVSKQDTMLMLERLVDVVDPEVYF
SQ  EFDAFEDLVNTKRPVIYMKRDDILGIYSSIAYVIDSIAPPDVNDPLRAVVNSLGPVSEQDNDFVQDETDVKLELNPKFCT
SQ  IENPVAQERTLIVQTKRYILFIIRIQNGLNLLEILVKPVTDSDEAAWQNLLAEESEKNARNYDLFDDSIFSMSFAELKYT
SQ  ALSNIVEMEKLGFANRRNNYQDMVNSIALDIRNKSRRRMQRQRELDAGHQSLLNLREKRAFLDSQLKSYNEYIEQAMETL
SQ  QSKKGKKKLIPFSKQYFHMRDLRKSGRVPRFGSFKYPALKLYDRGVLVSISHMPQKEKLYITISADEVGKFILEATSPTV
SQ  KVSSPRCELHLDDLLSAQYNKVLTLDVLDGRLKLNTNMFLHLIFSKFYS
//