ID  O42091;
PN  Tyrosine 3-monooxygenase;
GN  th;
OS  7936;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P24529}. Cell projection, axon {ECO:0000250|UniProtKB:P24529}. Note=Expressed in dopaminergic axons and axon terminals. {ECO:0000250|UniProtKB:P24529}.
DR  UNIPROT: O42091;
DR  Pfam: PF00351;
DR  Pfam: PF12549;
DR  PROSITE: PS00367;
DR  PROSITE: PS51410;
DE  Function: Plays an important role in the physiology of adrenergic neurons. {ECO:0000250}.
DE  Reference Proteome: No;
GO  GO:0030424;
GO  GO:0048471;
GO  GO:0005506;
GO  GO:0004511;
GO  GO:0009072;
GO  GO:0042416;
GO  GO:0042136;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPISNSSGSSTKSITRAGSELDRADSITSPRFVGRRQSLIEDARKEREAAAAAESSEASEQIVFDEEDGKALLNLFFTLR
SQ  SSKIPALSRALKVFETFEAKIHHLETRTRRKPKDSLEDLEYFVRCEVHLADVSTLISSIRRIAEDVRTTKEVKFHWFPKK
SQ  ISELDSCHHLVTKFDPDLDQDHPGFTDPVYRQRRRMIGEIAFRYKHGEPIPRVEYTEEEIGTWREVYSTLRDLYTTHACS
SQ  EHLEAFRLLERHCGYSPNSIPQLEDVSHFLKERTGFQLRPVAGLLSARDFLASLAFRVFQCTQYIRHASSPMHSPEPDCV
SQ  HELLGHVPMLADRTFAQFSQNIGLASLGASEEDIEKLSTLYWFTVEFGLCKQGDGVKAYGAGLLSSYGELVHSLSDEPER
SQ  REFDPEAAAAEPYQDQNYQSVYFVSESFTDAKEKLRVYAAGINRPFSVRFDPYTYSIEVLDNPLKIRGGLESVKDELKVL
SQ  TDALNVLA
//