ID  P04492;
PN  E1B protein, small T-antigen;
GN  E1BS;
OS  28282;
SL  Nucleus Position: SL-0415;
SL  Nucleus Position: SL-0416;
SL  Comments: Host cell membrane {ECO:0000250}. Host nucleus envelope {ECO:0000250}. Host nucleus lamina {ECO:0000250}. Note=Associated with the plasma and nuclear membranes, and with the insoluble nuclear lamina. {ECO:0000250}.
DR  UNIPROT: P04492;
DR  Pfam: PF01691;
DR  PROSITE: PS50062;
DE  Function: Putative adenovirus Bcl-2 homolog that inhibits apoptosis induced by TNF or FAS pathways, as well as p53-mediated apoptosis. Without E1B 19K function, virus production is compromised because of premature death of host cell. Interacts with Bax protein in cell lysates (By similarity). {ECO:0000250}.
DE  Reference Proteome: No;
GO  GO:0044203;
GO  GO:0020002;
GO  GO:0016020;
GO  GO:0019050;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MELETVLQSFQSVRQLLQYTSKNTSGFWRYLFGSTLSKVVNRVKEDYREEFENILADCPGLLASLDLCYHLVFQEKVVRS
SQ  LDFSSVGRTVASIAFLATILDKWSEKSHLSWDYMLDYMSMQLWRAWLKRRVCIYSLARPLTMPPLPTLQEEKEEERNPAV
SQ  VEK
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