ID  P06704;
PN  Cell division control protein 31;
GN  CDC31;
OS  559292;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus envelope {ECO:0000269|PubMed:10684247}. Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body {ECO:0000269|PubMed:8188750}. Note=Spindle pole body, SPB half- bridge (PubMed:8188750). Interacts with the nuclear pore complex (NPCs) at the nucleus envelope (PubMed:10684247). {ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:8188750}.
DR  UNIPROT: P06704;
DR  UNIPROT: D6W2V8;
DR  PDB: 2DOQ;
DR  PDB: 2GV5;
DR  PDB: 3FWB;
DR  PDB: 3FWC;
DR  PDB: 4MBE;
DR  Pfam: PF13499;
DR  PROSITE: PS00018;
DR  PROSITE: PS50222;
DE  Function: Functions as a component of the spindle pole body (SPB) half- bridge (PubMed:10684247, PubMed:11156974, PubMed:12486115, PubMed:14504268, PubMed:8070654). At the SPB, it is recruited by KAR1 and MPS3 to the SPB half-bridge and involved in the initial steps of SPB duplication (PubMed:11156974, PubMed:12486115, PubMed:14504268, PubMed:8070654). Also involved in connection with the protein kinase KIC1 in the maintenance of cell morphology and integrity (PubMed:9813095). May play a role in vesicle-mediated transport, in a VPS13-dependent manner (PubMed:28122955). {ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:11156974, ECO:0000269|PubMed:12486115, ECO:0000269|PubMed:14504268, ECO:0000269|PubMed:28122955, ECO:0000269|PubMed:8070654, ECO:0000269|PubMed:9813095}.
DE  Reference Proteome: Yes;
DE  Interaction: P38305; IntAct: EBI-761900; Score: 0.40
DE  Interaction: Q99181; IntAct: EBI-857104; Score: 0.00
DE  Interaction: P00927; IntAct: EBI-7366294; Score: 0.40
DE  Interaction: P41940; IntAct: EBI-7560454; Score: 0.44
DE  Interaction: P47116; IntAct: EBI-7562977; Score: 0.44
DE  Interaction: P10659; IntAct: EBI-7668648; Score: 0.40
DE  Interaction: P34730; IntAct: EBI-7930447; Score: 0.40
DE  Interaction: O94742; IntAct: EBI-7945620; Score: 0.40
DE  Interaction: P46674; IntAct: EBI-7945717; Score: 0.77
DE  Interaction: P39015; IntAct: EBI-7945762; Score: 0.40
DE  Interaction: P11353; IntAct: EBI-8031674; Score: 0.40
DE  Interaction: Q02959; IntAct: EBI-8051544; Score: 0.59
DE  Interaction: P53164; IntAct: EBI-8463661; Score: 0.40
DE  Interaction: P53030; IntAct: EBI-8221748; Score: 0.22
DE  Interaction: Q6WNK7; IntAct: EBI-1370393; Score: 0.76
DE  Interaction: Q02336; IntAct: EBI-1370467; Score: 0.35
DE  Interaction: P53040; IntAct: EBI-1370499; Score: 0.35
DE  Interaction: Q08231; IntAct: EBI-1370592; Score: 0.76
DE  Interaction: P11927; IntAct: EBI-2212825; Score: 0.40
DE  Interaction: P47069; IntAct: EBI-2212835; Score: 0.59
DE  Interaction: P40457; IntAct: EBI-2212931; Score: 0.40
DE  Interaction: Q12369; IntAct: EBI-2213075; Score: 0.56
DE  Interaction: P06704; IntAct: EBI-2213075; Score: 0.52
DE  Interaction: P54199; IntAct: EBI-2612619; Score: 0.35
DE  Interaction: P38590; IntAct: EBI-2612691; Score: 0.35
DE  Interaction: P32944; IntAct: EBI-2613930; Score: 0.35
DE  Interaction: Q08921; IntAct: EBI-2613976; Score: 0.35
DE  Interaction: P32447; IntAct: EBI-2881789; Score: 0.00
DE  Interaction: Q07457; IntAct: EBI-2882228; Score: 0.00
DE  Interaction: P26448; IntAct: EBI-2882390; Score: 0.00
DE  Interaction: Q00684; IntAct: EBI-2882792; Score: 0.00
DE  Interaction: P14832; IntAct: EBI-2882919; Score: 0.00
DE  Interaction: P32472; IntAct: EBI-2883301; Score: 0.00
DE  Interaction: P02293; IntAct: EBI-2884858; Score: 0.00
DE  Interaction: Q02796; IntAct: EBI-2885546; Score: 0.00
DE  Interaction: Q02206; IntAct: EBI-2886536; Score: 0.00
DE  Interaction: P38890; IntAct: EBI-2887466; Score: 0.00
DE  Interaction: P39723; IntAct: EBI-2887969; Score: 0.00
DE  Interaction: Q04477; IntAct: EBI-2887856; Score: 0.00
DE  Interaction: P46675; IntAct: EBI-2888241; Score: 0.00
DE  Interaction: P25302; IntAct: EBI-2888465; Score: 0.00
DE  Interaction: Q06677; IntAct: EBI-3651969; Score: 0.35
DE  Interaction: P10591; IntAct: EBI-3668305; Score: 0.35
DE  Interaction: P11484; IntAct: EBI-3686264; Score: 0.35
DE  Interaction: P38915; IntAct: EBI-4375569; Score: 0.35
DE  Interaction: Q12060; IntAct: EBI-4376704; Score: 0.35
DE  Interaction: P50102; IntAct: EBI-4380099; Score: 0.35
GO  GO:0005737;
GO  GO:0005825;
GO  GO:0005815;
GO  GO:0044732;
GO  GO:0005635;
GO  GO:0070390;
GO  GO:0005509;
GO  GO:0042802;
GO  GO:0008017;
GO  GO:0051301;
GO  GO:0048193;
GO  GO:0006406;
GO  GO:0045944;
GO  GO:0043161;
GO  GO:0043549;
GO  GO:0030474;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSKNRSSLQSGPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDD
SQ  FYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEINENEFIAICTD
SQ  S
//