ID  P18459;
PN  Tyrosine 3-monooxygenase;
GN  ple;
OS  7227;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:P24529}. Cell projection, axon {ECO:0000250|UniProtKB:P24529}. Note=Expressed in dopaminergic axons and axon terminals. {ECO:0000250|UniProtKB:P24529}.
DR  UNIPROT: P18459;
DR  UNIPROT: Q24000;
DR  UNIPROT: Q8SY95;
DR  Pfam: PF00351;
DR  PROSITE: PS00367;
DR  PROSITE: PS51410;
DE  Function: Plays an important role in the physiology of adrenergic neurons.
DE  Reference Proteome: Yes;
DE  Interaction: P49415; IntAct: EBI-198264; Score: 0.00
DE  Interaction: Q9W5A9; IntAct: EBI-198269; Score: 0.00
DE  Interaction: A0A0B4K7S6; IntAct: EBI-198274; Score: 0.00
DE  Interaction: Q9VGY3; IntAct: EBI-198279; Score: 0.00
DE  Interaction: Q9VDH8; IntAct: EBI-198284; Score: 0.00
DE  Interaction: Q9VR99; IntAct: EBI-198289; Score: 0.00
DE  Interaction: Q7K180; IntAct: EBI-198294; Score: 0.00
DE  Interaction: Q9W418; IntAct: EBI-198299; Score: 0.00
DE  Interaction: Q9W3Z4; IntAct: EBI-198304; Score: 0.00
DE  Interaction: Q9VPY2; IntAct: EBI-198309; Score: 0.00
DE  Interaction: Q9VBQ5; IntAct: EBI-198314; Score: 0.00
DE  Interaction: Q23972; IntAct: EBI-198319; Score: 0.00
DE  Interaction: Q24141; IntAct: EBI-198324; Score: 0.00
DE  Interaction: Q9VVL6; IntAct: EBI-198329; Score: 0.00
DE  Interaction: Q9VTH5; IntAct: EBI-198334; Score: 0.00
DE  Interaction: Q9V466; IntAct: EBI-198339; Score: 0.00
DE  Interaction: Q9VWQ2; IntAct: EBI-198344; Score: 0.00
DE  Interaction: Q9VW52; IntAct: EBI-198349; Score: 0.00
DE  Interaction: Q9VAF3; IntAct: EBI-198354; Score: 0.00
DE  Interaction: P05084; IntAct: EBI-198359; Score: 0.00
DE  Interaction: P12370; IntAct: EBI-873996; Score: 0.27
DE  Interaction: P48596; IntAct: EBI-874012; Score: 0.27
GO  GO:0030424;
GO  GO:0005737;
GO  GO:0043204;
GO  GO:0048471;
GO  GO:0005506;
GO  GO:0004511;
GO  GO:0048085;
GO  GO:0008344;
GO  GO:0006584;
GO  GO:0007619;
GO  GO:0048067;
GO  GO:0048066;
GO  GO:0042416;
GO  GO:0006585;
GO  GO:0042417;
GO  GO:0008049;
GO  GO:0042136;
GO  GO:0048082;
GO  GO:2000274;
GO  GO:0042542;
GO  GO:0009611;
GO  GO:0040040;
GO  GO:0043052;
GO  GO:0035220;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MMAVAAAQKNREMFAIKKSYSIENGYPSRRRSLVDDARFETLVVKQTKQTVLEEARSKANDDSLEDCIVQAQEHIPSEQD
SQ  VELQDEHANLENLPLEEYVPVEEDVEFESVEQEQSESQSQEPEGNQQPTKNDYGLTEDEILLANAASESSDAEAAMQSAA
SQ  LVVRLKEGISSLGRILKAIETFHGTVQHVESRQSRVEGVDHDVLIKLDMTRGNLLQLIRSLRQSGSFSSMNLMADNNLNV
SQ  KAPWFPKHASELDNCNHLMTKYEPDLDMNHPGFADKVYRQRRKEIAEIAFAYKYGDPIPFIDYSDVEVKTWRSVFKTVQD
SQ  LAPKHACAEYRAAFQKLQDEQIFVETRLPQLQEMSDFLRKNTGFSLRPAAGLLTARDFLASLAFRIFQSTQYVRHVNSPY
SQ  HTPEPDSIHELLGHMPLLADPSFAQFSQEIGLASLGASDEEIEKLSTVYWFTVEFGLCKEHGQIKAYGAGLLSSYGELLH
SQ  AISDKCEHRAFEPASTAVQPYQDQEYQPIYYVAESFEDAKDKFRRWVSTMSRPFEVRFNPHTERVEVLDSVDKLETLVHQ
SQ  MNTEILHLTNAISKLRRPF
//