ID  P21619;
PN  Lamin-B2;
GN  Lmnb2;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0180;
SL  Comments: Nucleus lamina {ECO:0000250|UniProtKB:Q03252}.
DR  UNIPROT: P21619;
DR  UNIPROT: P48680;
DR  UNIPROT: Q8CGB1;
DR  Pfam: PF00038;
DR  Pfam: PF00932;
DR  PROSITE: PS00226;
DR  PROSITE: PS51842;
DR  PROSITE: PS51841;
DE  Function: Lamins are components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. {ECO:0000250|UniProtKB:Q03252}.
DE  Reference Proteome: Yes;
DE  Interaction: Q80YT7; IntAct: EBI-16732484; Score: 0.35
DE  Interaction: P83510; IntAct: EBI-16734044; Score: 0.35
DE  Interaction: P08228; IntAct: EBI-20314123; Score: 0.35
DE  Interaction: Q8VI24; IntAct: EBI-26885104; Score: 0.35
GO  GO:0005638;
GO  GO:0005635;
GO  GO:0005652;
GO  GO:0031965;
GO  GO:0005634;
GO  GO:0042802;
GO  GO:0005200;
GO  GO:0031507;
GO  GO:0006998;
GO  GO:0007097;
GO  GO:0051664;
GO  GO:0090435;
TP  Membrane Topology: Lipid-Anchored; Source: UniProt - By Similarity {ECO:0000250};
SQ  MASLPPHAGPATPLSPTRLSRLQEKEELRELNDRLAHYIDRVRALELENDRLLLRISEKEEVTTREVSGIKTLYESELAD
SQ  ARRVLDETARERARLQIEIGKVQAELEEARKSAKKREGELTVAQGRVKDLESLFHRSEAELATALSDKQGLETEVAELRA
SQ  QLAKAEDGHAVAKKQLEKETLMRVDLENRCQSLQEELAFSKSVFEEEVRETRRRHERRLVEVDSSRQQEYDFKMAQALED
SQ  LRSQHDEQVRLYRVELEQTYQAKLDNAKLLSDQNDKAAHAAREELKEARMRVESLSYQLLGLQKQASAAENHIHELEEAL
SQ  AGERDKFRKMLDAKEQEMTEVRDAMQQQLAEYQELLDIKLALDMEISAYRKLLEGEEERLKLSPSPSSRITISRATSSSS
SQ  SSSGVGMSVGQGRGKRRRLETEDTSGSPSRASRVSSGSRLAQQTVATGVVNIDEVDPEGRFVRLKNSSDKDQSLGNWRIK
SQ  RQVLEGEDIAYKFTPKYVLRAGQTVTVWAAGAGATHSPPSTLVWKSQTNWGPGESFRTALVSADGEEVAVKAAKHSSVQG
SQ  RENGEEEEEEEAEFGEEDLFHQQGDPRTTSRGCRLM
//