ID  P28658;
PN  Ataxin-10;
GN  Atxn10;
OS  10090;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, perinuclear region {ECO:0000250}.
DR  UNIPROT: P28658;
DR  UNIPROT: Q543S3;
DR  UNIPROT: Q99LP5;
DR  UNIPROT: Q9D1I1;
DR  Pfam: PF09759;
DE  Function: Necessary for the survival of cerebellar neurons. Induces neuritogenesis by activating the Ras-MAP kinase pathway. May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis. {ECO:0000250}.
DE  Reference Proteome: Yes;
DE  Interaction: Q8BP00; IntAct: EBI-4283417; Score: 0.50
DE  Interaction: Q8CG73; IntAct: EBI-4284701; Score: 0.35
DE  Interaction: Q83B01; IntAct: EBI-21287600; Score: 0.37
DE  Interaction: Q83A33; IntAct: EBI-21288114; Score: 0.37
DE  Interaction: Q83A11; IntAct: EBI-21288333; Score: 0.37
DE  Interaction: Q6P1J9; IntAct: EBI-20729673; Score: 0.35
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0030425;
GO  GO:0043025;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0019899;
GO  GO:0042802;
GO  GO:0060271;
GO  GO:0007399;
GO  GO:0031175;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAAPRMPPSRLSGIMVPAPIQDLEALRALTALFKEQRNRETAPRTIFQRVLDILKKSTHAVELACRDPSQVEHLASSLQL
SQ  ITECFRCLRNACIECSVNQNSIRNLDTIGVAVDLVLLFRELRVEQDSLLTAFRCGLQFLGNVASRNEESQSIVWVHAFPE
SQ  LFMSCLNHPDKKIVAYCSMILFTSLNAERMKDLEENLNIAINVIEAHQKHPASEWPFLIISDHFLKSPELVEAMYGKLSN
SQ  QERITLLDIVIAKLVGEEQLTKDDISIFVRHAELIANSFMDQCRNVLKLTSEPHTEDKEALVTIRLLDVLCEMTSNTELL
SQ  GYLQVFPGLMERVIDVLRVIHEVGKESTNIFSPSDSLKAEGDIEHMTEGFKSHLIRLIGNLCYKNKENQDKVNELDGIPL
SQ  ILDSSNIDDNNPFMMQWVVYAVRNLTEDNSQNQDVIAKMEEQGLADASLLKKMGFEIEKSGDKLILKSNNDIPPP
//