ID  P35729;
PN  Nucleoporin NUP120;
GN  NUP120;
OS  559292;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10684247}. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
DR  UNIPROT: P35729;
DR  UNIPROT: D6VXN0;
DR  UNIPROT: P35730;
DR  PDB: 3F7F;
DR  PDB: 3H7N;
DR  PDB: 3HXR;
DR  PDB: 4XMM;
DR  PDB: 4XMN;
DR  PDB: 6X06;
DR  PDB: 7N84;
DR  PDB: 7N9F;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. NUP120 is involved in nuclear poly(A)+ RNA and pre-ribosome export, in GSP1 nuclear import, in NPC assembly and distribution, as well as in nuclear envelope organization. {ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:11071906, ECO:0000269|PubMed:11823431, ECO:0000269|PubMed:12730220, ECO:0000269|PubMed:8557737, ECO:0000269|PubMed:8565072}.
DE  Reference Proteome: Yes;
DE  Interaction: P53691; IntAct: EBI-393135; Score: 0.37
DE  Interaction: P38305; IntAct: EBI-761900; Score: 0.40
DE  Interaction: Q12315; IntAct: EBI-849734; Score: 0.32
DE  Interaction: P49687; IntAct: EBI-797641; Score: 0.95
DE  Interaction: P52891; IntAct: EBI-800196; Score: 0.91
DE  Interaction: P10592; IntAct: EBI-800487; Score: 0.35
DE  Interaction: P53011; IntAct: EBI-800487; Score: 0.91
DE  Interaction: Q06488; IntAct: EBI-800487; Score: 0.35
DE  Interaction: Q04439; IntAct: EBI-802262; Score: 0.35
DE  Interaction: Q04491; IntAct: EBI-812133; Score: 0.88
DE  Interaction: P32582; IntAct: EBI-815440; Score: 0.27
DE  Interaction: Q99257; IntAct: EBI-8220602; Score: 0.22
DE  Interaction: Q02630; IntAct: EBI-1269703; Score: 0.00
DE  Interaction: Q02629; IntAct: EBI-1269846; Score: 0.00
DE  Interaction: P40368; IntAct: EBI-6325174; Score: 0.00
DE  Interaction: P46673; IntAct: EBI-4325415; Score: 0.95
DE  Interaction: P22696; IntAct: EBI-2883245; Score: 0.00
DE  Interaction: Q04477; IntAct: EBI-2887856; Score: 0.00
DE  Interaction: P11484; IntAct: EBI-3781725; Score: 0.35
DE  Interaction: P39987; IntAct: EBI-3788002; Score: 0.35
DE  Interaction: P53900; IntAct: EBI-3821173; Score: 0.35
DE  Interaction: P55735; IntAct: EBI-11888124; Score: 0.40
DE  Interaction: P35729; IntAct: EBI-11890170; Score: 0.53
DE  Interaction: Q8WUM0; IntAct: EBI-11890181; Score: 0.40
DE  Interaction: P47054; IntAct: EBI-11888914; Score: 0.37
DE  Interaction: P36161; IntAct: EBI-15786270; Score: 0.75
GO  GO:0000781;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0031080;
GO  GO:0042802;
GO  GO:0017056;
GO  GO:0006302;
GO  GO:0006406;
GO  GO:0031990;
GO  GO:0000122;
GO  GO:0051664;
GO  GO:0006913;
GO  GO:0045893;
GO  GO:0045944;
GO  GO:0000973;
GO  GO:0006611;
GO  GO:0006606;
GO  GO:0000055;
GO  GO:0031509;
GO  GO:0034398;
TP  Membrane Topology: Peripheral; Source: UniProt - Sequence Analysis;
SQ  MACLSRIDANLLQYYEKPEPNNTVDLYVSNNSNNNGLKEGDKSISTPVPQPYGSEYSNCLLLSNSEYICYHFSSRSTLLT
SQ  FYPLSDAYHGKTINIHLPNASMNQRYTLTIQEVEQQLLVNVILKDGSFLTLQLPLSFLFSSANTLNGEWFHLQNPYDFTV
SQ  RVPHFLFYVSPQFSVVFLEDGGLLGLKKVDGVHYEPLLFNDNSYLKSLTRFFSRSSKSDYDSVISCKLFHERYLIVLTQN
SQ  CHLKIWDLTSFTLIQDYDMVSQSDSDPSHFRKVEAVGEYLSLYNNTLVTLLPLENGLFQMGTLLVDSSGILTYTFQNNIP
SQ  TNLSASAIWSIVDLVLTRPLELNVEASYLNLIVLWKSGTASKLQILNVNDESFKNYEWIESVNKSLVDLQSEHDLDIVTK
SQ  TGDVERGFCNLKSRYGTQIFERAQQILSENKIIMAHNEDEEYLANLETILRDVKTAFNEASSITLYGDEIILVNCFQPYN
SQ  HSLYKLNTTVENWFYNMHSETDGSELFKYLRTLNGFASTLSNDVLRSISKKFLDIITGELPDSMTTVEKFTDIFKNCLEN
SQ  QFEITNLKILFDELNSFDIPVVLNDLINNQMKPGIFWKKDFISAIKFDGFTSIISLESLHQLLSIHYRITLQVLLTFVLF
SQ  DLDTEIFGQHISTLLDLHYKQFLLLNLYRQDKCLLAEVLLKDSSEFSFGVKFFNYGQLIAYIDSLNSNVYNASITENSFF
SQ  MTFFRSYIIENTSHKNIRFFLENVECPFYLRHNEVQEFMFAMTLFSCGNFDQSYEIFQLHDYPEAINDKLPTFLEDLKSE
SQ  NYHGDSIWKDLLCTFTVPYRHSAFYYQLSLLFDRNNSQEFALKCISKSAEYSLKEIQIEELQDFKEKQHIHYLNLLIHFR
SQ  MFEEVLDVLRLGHECLSDTVRTNFLQLLLQEDIYSRDFFSTLLRLCNAHSDNGELYLRTVDIKIVDSILSQNLRSGDWEC
SQ  FKKLYCFRMLNKSERAAAEVLYQYILMQADLDVIRKRKCYLMVINVLSSFDSAYDQWILNGSKVVTLTDLRDELRGL
//