ID  P39015;
PN  Suppressor protein STM1;
GN  STM1;
OS  559292;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm. Nucleus. Cytoplasm, perinuclear region. Note=Concentrated in the perinuclear region.
DR  UNIPROT: P39015;
DR  UNIPROT: D6VYE5;
DR  PDB: 4U3M;
DR  PDB: 4U3N;
DR  PDB: 4U3U;
DR  PDB: 4U4N;
DR  PDB: 4U4O;
DR  PDB: 4U4Q;
DR  PDB: 4U4R;
DR  PDB: 4U4U;
DR  PDB: 4U4Y;
DR  PDB: 4U4Z;
DR  PDB: 4U50;
DR  PDB: 4U51;
DR  PDB: 4U52;
DR  PDB: 4U53;
DR  PDB: 4U55;
DR  PDB: 4U56;
DR  PDB: 4U6F;
DR  PDB: 4V88;
DR  PDB: 4V8Y;
DR  PDB: 4V8Z;
DR  PDB: 5DAT;
DR  PDB: 5DC3;
DR  PDB: 5DGE;
DR  PDB: 5FCI;
DR  PDB: 5FCJ;
DR  PDB: 5I4L;
DR  PDB: 5LYB;
DR  PDB: 5NDG;
DR  PDB: 5NDV;
DR  PDB: 5NDW;
DR  PDB: 5OBM;
DR  PDB: 5TGA;
DR  PDB: 5TGM;
DR  PDB: 6HHQ;
DR  Pfam: PF09598;
DE  Function: Binds specifically G4 quadruplex (these are four-stranded right-handed helices, stabilized by guanine base quartets) and purine motif triplex (characterized by a third, antiparallel purine-rich DNA strand located within the major groove of a homopurine stretch of duplex DNA) nucleic acid structures. These structures may be present at telomeres or in rRNAs. Acts with CDC13 to control telomere length homeostasis. Involved in the control of the apoptosis-like cell death. {ECO:0000269|PubMed:15044472}.
DE  Reference Proteome: Yes;
DE  Interaction: P06704; IntAct: EBI-7945762; Score: 0.40
DE  Interaction: P22147; IntAct: EBI-7383874; Score: 0.40
DE  Interaction: P30822; IntAct: EBI-11611503; Score: 0.35
DE  Interaction: P39015; IntAct: EBI-7102530; Score: 0.40
DE  Interaction: P40968; IntAct: EBI-7102563; Score: 0.40
DE  Interaction: P10863; IntAct: EBI-7109009; Score: 0.40
DE  Interaction: Q12114; IntAct: EBI-784698; Score: 0.35
DE  Interaction: P38968; IntAct: EBI-788839; Score: 0.35
DE  Interaction: P38199; IntAct: EBI-796822; Score: 0.35
DE  Interaction: P07280; IntAct: EBI-801098; Score: 0.35
DE  Interaction: P32790; IntAct: EBI-802790; Score: 0.35
DE  Interaction: Q08687; IntAct: EBI-807945; Score: 0.35
DE  Interaction: P11632; IntAct: EBI-808830; Score: 0.35
DE  Interaction: P38700; IntAct: EBI-813960; Score: 0.27
DE  Interaction: P38822; IntAct: EBI-815028; Score: 0.27
DE  Interaction: P32357; IntAct: EBI-817406; Score: 0.27
DE  Interaction: P38285; IntAct: EBI-818288; Score: 0.27
DE  Interaction: P40522; IntAct: EBI-819618; Score: 0.27
DE  Interaction: Q12389; IntAct: EBI-819624; Score: 0.27
DE  Interaction: P00330; IntAct: EBI-819848; Score: 0.27
DE  Interaction: Q02486; IntAct: EBI-820332; Score: 0.27
DE  Interaction: P02293; IntAct: EBI-820511; Score: 0.27
DE  Interaction: P07270; IntAct: EBI-821981; Score: 0.35
DE  Interaction: P22082; IntAct: EBI-822228; Score: 0.35
DE  Interaction: P39940; IntAct: EBI-937964; Score: 0.44
DE  Interaction: P43582; IntAct: EBI-938833; Score: 0.44
DE  Interaction: P40318; IntAct: EBI-939185; Score: 0.44
DE  Interaction: P46995; IntAct: EBI-939475; Score: 0.44
DE  Interaction: P22696; IntAct: EBI-939677; Score: 0.44
DE  Interaction: P33203; IntAct: EBI-940012; Score: 0.44
DE  Interaction: Q06525; IntAct: EBI-940637; Score: 0.44
DE  Interaction: P38633; IntAct: EBI-7030235; Score: 0.40
DE  Interaction: P32558; IntAct: EBI-7033179; Score: 0.40
DE  Interaction: P42945; IntAct: EBI-7118959; Score: 0.40
DE  Interaction: Q06188; IntAct: EBI-7172803; Score: 0.40
DE  Interaction: Q06109; IntAct: EBI-7201165; Score: 0.40
DE  Interaction: P53741; IntAct: EBI-7226242; Score: 0.56
DE  Interaction: P40023; IntAct: EBI-7284277; Score: 0.40
DE  Interaction: P20448; IntAct: EBI-7328235; Score: 0.40
DE  Interaction: P48570; IntAct: EBI-7405961; Score: 0.40
DE  Interaction: P32505; IntAct: EBI-7425228; Score: 0.40
DE  Interaction: P38205; IntAct: EBI-7427415; Score: 0.40
DE  Interaction: P39744; IntAct: EBI-7430572; Score: 0.40
DE  Interaction: P53742; IntAct: EBI-7433745; Score: 0.40
DE  Interaction: P21951; IntAct: EBI-7459287; Score: 0.40
DE  Interaction: Q07350; IntAct: EBI-7554433; Score: 0.40
DE  Interaction: P53131; IntAct: EBI-7558289; Score: 0.40
DE  Interaction: P31374; IntAct: EBI-7560747; Score: 0.40
DE  Interaction: Q04373; IntAct: EBI-7563094; Score: 0.40
DE  Interaction: P38251; IntAct: EBI-7577892; Score: 0.40
DE  Interaction: Q03195; IntAct: EBI-7580304; Score: 0.40
DE  Interaction: P25046; IntAct: EBI-7583439; Score: 0.40
DE  Interaction: P0C0T4; IntAct: EBI-7651776; Score: 0.40
DE  Interaction: P47050; IntAct: EBI-7664713; Score: 0.40
DE  Interaction: P32368; IntAct: EBI-7668370; Score: 0.40
DE  Interaction: P40509; IntAct: EBI-7677023; Score: 0.40
DE  Interaction: P23293; IntAct: EBI-7692513; Score: 0.40
DE  Interaction: P22579; IntAct: EBI-7697200; Score: 0.40
DE  Interaction: P35207; IntAct: EBI-7700401; Score: 0.40
DE  Interaction: Q02793; IntAct: EBI-7701654; Score: 0.40
DE  Interaction: P40072; IntAct: EBI-7703803; Score: 0.40
DE  Interaction: P46965; IntAct: EBI-7734821; Score: 0.40
DE  Interaction: P38123; IntAct: EBI-7768968; Score: 0.40
DE  Interaction: P36100; IntAct: EBI-7777929; Score: 0.40
DE  Interaction: Q07381; IntAct: EBI-7786590; Score: 0.40
DE  Interaction: Q06672; IntAct: EBI-7787631; Score: 0.40
DE  Interaction: P53874; IntAct: EBI-7789499; Score: 0.40
DE  Interaction: Q01477; IntAct: EBI-7792626; Score: 0.56
DE  Interaction: P53254; IntAct: EBI-7813272; Score: 0.40
DE  Interaction: Q08831; IntAct: EBI-7831006; Score: 0.40
DE  Interaction: P38197; IntAct: EBI-7834574; Score: 0.40
DE  Interaction: P40487; IntAct: EBI-7858467; Score: 0.40
DE  Interaction: P40462; IntAct: EBI-7859020; Score: 0.40
DE  Interaction: Q07953; IntAct: EBI-7861598; Score: 0.40
DE  Interaction: Q3E747; IntAct: EBI-7862695; Score: 0.40
DE  Interaction: P38806; IntAct: EBI-7869465; Score: 0.40
DE  Interaction: P53911; IntAct: EBI-7870828; Score: 0.40
DE  Interaction: Q12080; IntAct: EBI-7884725; Score: 0.40
DE  Interaction: Q12152; IntAct: EBI-7884942; Score: 0.40
DE  Interaction: Q12179; IntAct: EBI-7885829; Score: 0.40
DE  Interaction: P50275; IntAct: EBI-7913090; Score: 0.44
DE  Interaction: Q04199; IntAct: EBI-7937753; Score: 0.40
DE  Interaction: P38626; IntAct: EBI-7943352; Score: 0.40
DE  Interaction: Q06697; IntAct: EBI-7949322; Score: 0.40
DE  Interaction: P47130; IntAct: EBI-7983878; Score: 0.40
DE  Interaction: Q02554; IntAct: EBI-7987846; Score: 0.40
DE  Interaction: P18899; IntAct: EBI-7998863; Score: 0.40
DE  Interaction: P24482; IntAct: EBI-8000629; Score: 0.40
DE  Interaction: P32803; IntAct: EBI-8005417; Score: 0.40
DE  Interaction: P39704; IntAct: EBI-8008355; Score: 0.40
DE  Interaction: P15442; IntAct: EBI-8014597; Score: 0.40
DE  Interaction: Q04233; IntAct: EBI-8017049; Score: 0.40
DE  Interaction: P41911; IntAct: EBI-8019433; Score: 0.40
DE  Interaction: P32806; IntAct: EBI-8020973; Score: 0.40
DE  Interaction: Q12341; IntAct: EBI-8021985; Score: 0.40
DE  Interaction: P53685; IntAct: EBI-8059242; Score: 0.40
DE  Interaction: P38304; IntAct: EBI-8434332; Score: 0.40
DE  Interaction: Q06164; IntAct: EBI-8437245; Score: 0.40
DE  Interaction: P38694; IntAct: EBI-8443741; Score: 0.40
DE  Interaction: P32495; IntAct: EBI-8449766; Score: 0.40
DE  Interaction: Q07896; IntAct: EBI-8452527; Score: 0.40
DE  Interaction: P53927; IntAct: EBI-8453525; Score: 0.40
DE  Interaction: P42841; IntAct: EBI-8486372; Score: 0.40
DE  Interaction: P33775; IntAct: EBI-8494631; Score: 0.40
DE  Interaction: P40454; IntAct: EBI-2886504; Score: 0.00
DE  Interaction: P25294; IntAct: EBI-3662273; Score: 0.35
DE  Interaction: P10591; IntAct: EBI-3678076; Score: 0.53
DE  Interaction: P11484; IntAct: EBI-3784224; Score: 0.35
DE  Interaction: P38788; IntAct: EBI-3791884; Score: 0.35
DE  Interaction: P40150; IntAct: EBI-3801989; Score: 0.35
DE  Interaction: P22943; IntAct: EBI-3831611; Score: 0.35
DE  Interaction: P36160; IntAct: EBI-7433031; Score: 0.35
DE  Interaction: Q00416; IntAct: EBI-16421063; Score: 0.35
DE  Interaction: P39109; IntAct: EBI-20816574; Score: 0.37
DE  Interaction: P38011; IntAct: EBI-26974569; Score: 0.78
GO  GO:0005737;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0005844;
GO  GO:0003677;
GO  GO:0043022;
GO  GO:0042162;
GO  GO:0045142;
GO  GO:0043066;
GO  GO:0043558;
GO  GO:0000723;
GO  GO:0031929;
GO  GO:0006414;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSNPFDLLGNDVEDADVVVLPPKEIVKSNTSSKKADVPPPSADPSKARKNRPRPSGNEGAIRDKTAGRRNNRSKDVTDSA
SQ  TTKKSNTRRATDRHSRTGKTDTKKKVNQGWGDDKKELSAEKEAQADAAAEIAEDAAEAEDAGKPKTAQLSLQDYLNQQAN
SQ  NQFNKVPEAKKVELDAERIETAEKEAYVPATKVKNVKSKQLKTKEYLEFDATFVESNTRKNFGDRNNNSRNNFNNRRGGR
SQ  GARKGNNTANATNSANTVQKNRNIDVSNLPSLA
//