ID  P39685;
PN  Nucleoporin POM152;
GN  POM152;
OS  559292;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10684247}. Nucleus membrane; Multi-pass membrane protein. Note=Central core structure of the nuclear pore complex.
DR  UNIPROT: P39685;
DR  UNIPROT: D6VZV2;
DR  PDB: 5TVZ;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. POM152 is important for the de novo assembly of NPCs. {ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:11352933, ECO:0000269|PubMed:8682855, ECO:0000269|PubMed:9988776}.
DE  Reference Proteome: Yes;
DE  Interaction: P47042; IntAct: EBI-390972; Score: 0.37
DE  Interaction: Q03790; IntAct: EBI-390975; Score: 0.37
DE  Interaction: P38305; IntAct: EBI-761900; Score: 0.40
DE  Interaction: P02994; IntAct: EBI-804163; Score: 0.40
DE  Interaction: Q12158; IntAct: EBI-821936; Score: 0.35
DE  Interaction: P40358; IntAct: EBI-3657572; Score: 0.35
DE  Interaction: P10591; IntAct: EBI-3674542; Score: 0.35
DE  Interaction: P11484; IntAct: EBI-3692806; Score: 0.35
DE  Interaction: P15108; IntAct: EBI-3734723; Score: 0.35
DE  Interaction: P10592; IntAct: EBI-3756439; Score: 0.35
DE  Interaction: P32589; IntAct: EBI-3757151; Score: 0.35
DE  Interaction: P39102; IntAct: EBI-3761596; Score: 0.35
DE  Interaction: P39078; IntAct: EBI-3822546; Score: 0.35
GO  GO:0071944;
GO  GO:0016021;
GO  GO:0005739;
GO  GO:0005635;
GO  GO:0005641;
GO  GO:0031965;
GO  GO:0034399;
GO  GO:0005643;
GO  GO:0070762;
GO  GO:0043495;
GO  GO:0017056;
GO  GO:0051028;
GO  GO:0006999;
GO  GO:0006913;
GO  GO:0006606;
GO  GO:0030474;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MEHRYNVFNDTPRGNHWMGSSVSGSPRPSYSSRPNVNTTRRFQYSDDEPAEKIRPLRSRSFKSTESNISDEKSRISERDS
SQ  KDRYINGDKKVDIYSLPLISTDVLEISKQRTFAVILFLIIQCYKIYDLVILKSGLPLSGLLFKNYRFNFISKYFIIDSFF
SQ  LYVLPSFNIPRLTFKPWVVYLQILAMLLLNIFISSDHEFVLISLIMTTWRKLYTKELSVTGSAINHHRIFDSSAHFKGAL
SQ  TIKILPENTAMFNPLHESYCLPMDTNLFKINSIDVPIRINSTEEIEYIELEYRDLYTNSVELRSLSKKDFKIIDNPKSFL
SQ  KKDQSVLKSHSNDFEEGSTIRYLAVTLQDIGFYQIKKIVDSKKLNLKIHQSHLVVPYCPIASITGTGSNDRCIGDSDNVS
SQ  FEIQGVPPMKLAYSKIVNGQTFSYVDSSLQPEYFESPLQSSKSKQSFTQGELNDLKWGRNQPVNINLDSSITQDGKFAYK
SQ  IDKITDGLGNVVDFTSLPEELKKRYDLSYNFNVHEVPRAALEERFDPKSPTKRSIAIVFEEIKNWISDIPYVISLSYTDA
SQ  QDKSKKIMNVTTDSLTKVLQADLPGSYNLEYIESKFCPGEIVGKSNVLVTMPVAPTMEVKSFPILDQCVGQVGLNFELSF
SQ  TGAPPYYYNTKIYKLENGERKLYDAKRYTSEGTRNRFSYSPPKEGNYEIVFDTVSNKLFTEPIKLEPVKEYTFKTSMRVK
SQ  PSASLKLHHDLKLCLGDHSSVPVALKGQGPFTLTYDIIETFSSKRKTFEIKEIKTNEYVIKTPVFTTGGDYILSLVSIKD
SQ  STGCVVGLSQPDAKIQVRRDIPSAAFNFFEPIKEAKIKHGSVTEIPLKLSGEGPFTVKFKHMDYDGNIVKEFENKFQNSY
SQ  KPALKVSKEGLYQLVDIRDSSCQGNVIYRNSLYKVSFLEKPKFAIQDNHHITKVTENLFSKEEVCQGMEGTVDLALFGSP
SQ  PFILEYDLMAPNGHISTKKIQVATKYASLKLPNQIPGEYITTIKAIFDGNYGESDIHFREHQSELIIKQTVHPIPDVAFA
SQ  DGGKTLRACAANVDQISFLEPINLKFLQGESPFSITFSVYHESTSRTDQYTIDNIDSENFSFEKLYEGMKLGNHAITIDS
SQ  VVDANGCVNSLISGPRNQILVSITDAPKIHILDPSTEYCVGDYVAYQLNGVAPFMIKYEFNGIPLKSKERSSQFVRLASE
SQ  PGIISITSLQDSSSQCIVDFTNPKLKSEFDDLSLNIHPIPSVTVSQGNYVTEDIREGDQAEVIFSFEGTPPFSLTYVRTE
SQ  ETDGKHGKRRSQVVETHKVTDIYSHEYKVITSLQGTYEAIEITDAYCFAKNDLFFNN
//