ID  P40066;
PN  mRNA export factor GLE2;
GN  GLE2;
OS  559292;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:10684247}. Nucleus membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus membrane; Peripheral membrane protein; Nucleoplasmic side. Note=Symmetric distribution.
DR  UNIPROT: P40066;
DR  UNIPROT: D3DM14;
DR  Pfam: PF00400;
DR  PROSITE: PS50082;
DR  PROSITE: PS50294;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. It is specifically important for nuclear mRNA export. {ECO:0000269|PubMed:10684247, ECO:0000269|PubMed:10801828, ECO:0000269|PubMed:11689687, ECO:0000269|PubMed:8970155, ECO:0000269|PubMed:9463388}.
DE  Reference Proteome: Yes;
DE  Interaction: P14907; IntAct: EBI-797307; Score: 0.44
DE  Interaction: P34077; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P38305; IntAct: EBI-761900; Score: 0.40
DE  Interaction: Q12315; IntAct: EBI-849734; Score: 0.32
DE  Interaction: Q02630; IntAct: EBI-795280; Score: 0.61
DE  Interaction: P11484; IntAct: EBI-797307; Score: 0.35
DE  Interaction: P10591; IntAct: EBI-797307; Score: 0.35
DE  Interaction: P40368; IntAct: EBI-797307; Score: 0.44
DE  Interaction: P40477; IntAct: EBI-797307; Score: 0.44
DE  Interaction: P10592; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P47054; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P48837; IntAct: EBI-813993; Score: 0.27
DE  Interaction: Q04599; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P36516; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P22353; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P36523; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P36525; IntAct: EBI-813993; Score: 0.27
DE  Interaction: Q06678; IntAct: EBI-813993; Score: 0.27
DE  Interaction: P32337; IntAct: EBI-7490608; Score: 0.40
DE  Interaction: P47019; IntAct: EBI-8229717; Score: 0.22
DE  Interaction: P24870; IntAct: EBI-2611503; Score: 0.35
DE  Interaction: P24869; IntAct: EBI-2617071; Score: 0.35
DE  Interaction: P22696; IntAct: EBI-2883245; Score: 0.00
DE  Interaction: P38915; IntAct: EBI-4375569; Score: 0.35
DE  Interaction: P38129; IntAct: EBI-4380674; Score: 0.35
DE  Interaction: P35177; IntAct: EBI-4383599; Score: 0.35
DE  Interaction: Q03330; IntAct: EBI-4385804; Score: 0.35
DE  Interaction: P53040; IntAct: EBI-4390624; Score: 0.35
GO  GO:0005737;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0003723;
GO  GO:0043130;
GO  GO:0051664;
GO  GO:0006913;
GO  GO:0016973;
GO  GO:0000973;
GO  GO:0015031;
GO  GO:2000728;
GO  GO:0006405;
GO  GO:0000972;
TP  Membrane Topology: Peripheral; Source: UniProt - Sequence Analysis;
SQ  MSFFNRSNTTSALGTSTAMANEKDLANDIVINSPAEDSISDIAFSPQQDFMFSASSWDGKVRIWDVQNGVPQGRAQHESS
SQ  SPVLCTRWSNDGTKVASGGCDNALKLYDIASGQTQQIGMHSAPIKVLRFVQCGPSNTECIVTGSWDKTIKYWDMRQPQPV
SQ  STVMMPERVYSMDNKQSLLVVATAERHIAIINLANPTTIFKATTSPLKWQTRCVACYNEADGYAIGSVEGRCSIRYIDDG
SQ  MQKKSGFSFKCHRQTNPNRAPGSNGQSLVYPVNSIAFHPLYGTFVTAGGDGTFNFWDKNQRHRLKGYPTLQASIPVCSFN
SQ  RNGSVFAYALSYDWHQGHMGNRPDYPNVIRLHATTDEEVKEKKKR
//