ID  P50402;
PN  Emerin;
GN  EMD;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0183;
SL  Comments: Nucleus inner membrane {ECO:0000269|PubMed:19167377}; Single-pass membrane protein; Nucleoplasmic side {ECO:0000269|PubMed:19167377}. Nucleus outer membrane. Note=Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus.
DR  UNIPROT: P50402;
DR  UNIPROT: Q6FI02;
DR  PDB: 1JEI;
DR  PDB: 2ODC;
DR  PDB: 2ODG;
DR  PDB: 6GHD;
DR  PDB: 6RPR;
DR  PDB: 7NDY;
DR  Pfam: PF03020;
DR  PROSITE: PS50954;
DR  OMIM: 300384;
DR  OMIM: 310300;
DR  DisGeNET: 2010;
DE  Function: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta- catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1- dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Required for proper localization of non- farnesylated prelamin-A/C. Together with NEMP1, contributes to nuclear envelope stiffness in germ cells (PubMed:32923640). EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. {ECO:0000269|PubMed:15328537, ECO:0000269|PubMed:16680152, ECO:0000269|PubMed:16858403, ECO:0000269|PubMed:17785515, ECO:0000269|PubMed:19323649, ECO:0000269|PubMed:32923640}.
DE  Disease: Emery-Dreifuss muscular dystrophy 1, X-linked (EDMD1) [MIM:310300]: A form of Emery-Dreifuss muscular dystrophy, a degenerative myopathy characterized by weakness and atrophy of muscle without involvement of the nervous system, early contractures of the elbows, Achilles tendons and spine, and cardiomyopathy associated with cardiac conduction defects. {ECO:0000269|PubMed:10323252, ECO:0000269|PubMed:11587540, ECO:0000269|PubMed:15009215, ECO:0000269|PubMed:15328537}. Note=The disease is caused by variants affecting the gene represented in this entry.
DE  Reference Proteome: Yes;
DE  Interaction: A1L3G9; IntAct: EBI-12595918; Score: 0.40
DE  Interaction: O75531; IntAct: EBI-10759397; Score: 0.94
DE  Interaction: O94901; IntAct: EBI-22057164; Score: 0.46
DE  Interaction: P00533; IntAct: EBI-32717697; Score: 0.42
DE  Interaction: P01112; IntAct: EBI-27045317; Score: 0.27
DE  Interaction: P02545; IntAct: EBI-16795756; Score: 0.80
DE  Interaction: P03246; IntAct: EBI-11722343; Score: 0.35
DE  Interaction: P04626; IntAct: EBI-32718334; Score: 0.35
DE  Interaction: P0DTC7; IntAct: EBI-25510184; Score: 0.35
DE  Interaction: P13285; IntAct: EBI-11733017; Score: 0.35
DE  Interaction: P35240; IntAct: EBI-23824818; Score: 0.56
DE  Interaction: Q9NYF8; IntAct: EBI-489904; Score: 0.59
DE  Interaction: Q7L5N1; IntAct: EBI-731797; Score: 0.00
DE  Interaction: Q7L190; IntAct: EBI-731800; Score: 0.00
DE  Interaction: Q99962; IntAct: EBI-710249; Score: 0.51
DE  Interaction: Q99963; IntAct: EBI-731806; Score: 0.00
DE  Interaction: Q969F0; IntAct: EBI-753397; Score: 0.85
DE  Interaction: O43889; IntAct: EBI-12701204; Score: 0.56
DE  Interaction: Q8N7W2; IntAct: EBI-10211848; Score: 0.81
DE  Interaction: P35222; IntAct: EBI-8577506; Score: 0.59
DE  Interaction: P13569; IntAct: EBI-1171716; Score: 0.53
DE  Interaction: Q9UKV8; IntAct: EBI-7642406; Score: 0.35
DE  Interaction: P04296; IntAct: EBI-9631489; Score: 0.35
DE  Interaction: Q9HCK5; IntAct: EBI-2269711; Score: 0.35
DE  Interaction: O70126; IntAct: EBI-2557780; Score: 0.40
DE  Interaction: P03372; IntAct: EBI-2877710; Score: 0.35
DE  Interaction: Q9BQS8; IntAct: EBI-3242919; Score: 0.35
DE  Interaction: Q15051; IntAct: EBI-4286917; Score: 0.35
DE  Interaction: P51858; IntAct: EBI-4409719; Score: 0.35
DE  Interaction: Q16659; IntAct: EBI-7207761; Score: 0.37
DE  Interaction: P0DOE9; IntAct: EBI-6138583; Score: 0.35
DE  Interaction: P19320; IntAct: EBI-6191076; Score: 0.53
DE  Interaction: Q77M19; IntAct: EBI-6270503; Score: 0.35
DE  Interaction: Q13617; IntAct: EBI-21327106; Score: 0.35
DE  Interaction: Q13618; IntAct: EBI-21329068; Score: 0.35
DE  Interaction: P22893; IntAct: EBI-6506418; Score: 0.35
DE  Interaction: Q5S007; IntAct: EBI-6515609; Score: 0.53
DE  Interaction: Q9UH99; IntAct: EBI-6753091; Score: 0.64
DE  Interaction: Q9D666; IntAct: EBI-6752609; Score: 0.52
DE  Interaction: P57078; IntAct: EBI-12503575; Score: 0.35
DE  Interaction: Q8IWZ5; IntAct: EBI-10211808; Score: 0.72
DE  Interaction: Q53Z40; IntAct: EBI-10211828; Score: 0.56
DE  Interaction: Q5JST6; IntAct: EBI-10211838; Score: 0.56
DE  Interaction: Q8NEC5; IntAct: EBI-10211860; Score: 0.81
DE  Interaction: Q9P286; IntAct: EBI-10211880; Score: 0.56
DE  Interaction: Q8NHQ1; IntAct: EBI-10211870; Score: 0.72
DE  Interaction: Q9P127; IntAct: EBI-10211900; Score: 0.81
DE  Interaction: Q9UNY5; IntAct: EBI-10211910; Score: 0.56
DE  Interaction: Q9Y228; IntAct: EBI-10211920; Score: 0.81
DE  Interaction: Q13895; IntAct: EBI-10230959; Score: 0.72
DE  Interaction: Q8N8X9; IntAct: EBI-10268015; Score: 0.56
DE  Interaction: Q8WTP8; IntAct: EBI-10275770; Score: 0.56
DE  Interaction: Q9ULW3; IntAct: EBI-10323933; Score: 0.72
DE  Interaction: P50402; IntAct: EBI-10484783; Score: 0.37
DE  Interaction: O14862; IntAct: EBI-9995694; Score: 0.35
DE  Interaction: P10398; IntAct: EBI-10101587; Score: 0.35
DE  Interaction: Q13418; IntAct: EBI-10103376; Score: 0.35
DE  Interaction: P51617; IntAct: EBI-10103481; Score: 0.53
DE  Interaction: O60674; IntAct: EBI-10103554; Score: 0.35
DE  Interaction: P53671; IntAct: EBI-10103591; Score: 0.35
DE  Interaction: P04049; IntAct: EBI-10104226; Score: 0.53
DE  Interaction: Q9H0K1; IntAct: EBI-10104403; Score: 0.35
DE  Interaction: Q8NF91; IntAct: EBI-10759458; Score: 0.52
DE  Interaction: Q8WXH0; IntAct: EBI-10760372; Score: 0.58
DE  Interaction: P03177; IntAct: EBI-11721652; Score: 0.35
DE  Interaction: P03179; IntAct: EBI-11721697; Score: 0.35
DE  Interaction: P03182; IntAct: EBI-11721938; Score: 0.35
DE  Interaction: P03225; IntAct: EBI-11722220; Score: 0.35
DE  Interaction: P06460; IntAct: EBI-11723082; Score: 0.35
DE  Interaction: P06461; IntAct: EBI-11723785; Score: 0.35
DE  Interaction: P06792; IntAct: EBI-11724527; Score: 0.35
DE  Interaction: P06927; IntAct: EBI-11724813; Score: 0.35
DE  Interaction: P0C739; IntAct: EBI-11725101; Score: 0.35
DE  Interaction: P0CK56; IntAct: EBI-11725466; Score: 0.35
DE  Interaction: P0CK58; IntAct: EBI-11732874; Score: 0.35
DE  Interaction: P30119; IntAct: EBI-11733103; Score: 0.35
DE  Interaction: P69901; IntAct: EBI-11733364; Score: 0.35
DE  Interaction: Q2MG95; IntAct: EBI-11733653; Score: 0.35
DE  Interaction: Q2MG96; IntAct: EBI-11733890; Score: 0.35
DE  Interaction: Q8AZK7; IntAct: EBI-11734159; Score: 0.35
DE  Interaction: Q8AZJ3; IntAct: EBI-11734105; Score: 0.35
DE  Interaction: E9QKK1; IntAct: EBI-10995761; Score: 0.35
DE  Interaction: Q9Z1B5; IntAct: EBI-10996176; Score: 0.35
DE  Interaction: P36895; IntAct: EBI-11008521; Score: 0.35
DE  Interaction: P31150; IntAct: EBI-11035437; Score: 0.35
DE  Interaction: Q9Z2X1; IntAct: EBI-11066678; Score: 0.35
DE  Interaction: F8VQC7; IntAct: EBI-11104527; Score: 0.35
DE  Interaction: Q6ZNC8; IntAct: EBI-11121915; Score: 0.35
DE  Interaction: Q5T3F8; IntAct: EBI-11155257; Score: 0.35
DE  Interaction: Q6NUS6; IntAct: EBI-11368748; Score: 0.27
DE  Interaction: Q86UK5; IntAct: EBI-11372136; Score: 0.27
DE  Interaction: Q86X19; IntAct: EBI-11372615; Score: 0.27
DE  Interaction: Q96GX1; IntAct: EBI-11375285; Score: 0.27
DE  Interaction: Q9P0N5; IntAct: EBI-11378021; Score: 0.27
DE  Interaction: Q96Q45; IntAct: EBI-11396533; Score: 0.27
DE  Interaction: P48039; IntAct: EBI-11575834; Score: 0.37
DE  Interaction: Q8N6L0; IntAct: EBI-11774371; Score: 0.79
DE  Interaction: Q71U36; IntAct: EBI-11897791; Score: 0.53
DE  Interaction: Q6FHY5; IntAct: EBI-24279203; Score: 0.56
DE  Interaction: Q9BYN7; IntAct: EBI-24339377; Score: 0.56
DE  Interaction: Q04864; IntAct: EBI-24344788; Score: 0.56
DE  Interaction: Q16623; IntAct: EBI-24487831; Score: 0.56
DE  Interaction: Q6P2D0; IntAct: EBI-24525478; Score: 0.56
DE  Interaction: P20138; IntAct: EBI-24662714; Score: 0.56
DE  Interaction: Q5JRM2; IntAct: EBI-23676624; Score: 0.56
DE  Interaction: Q8N5K1; IntAct: EBI-23679672; Score: 0.56
DE  Interaction: Q96HE8; IntAct: EBI-24667793; Score: 0.56
DE  Interaction: Q6NX45; IntAct: EBI-24670601; Score: 0.56
DE  Interaction: B7U540; IntAct: EBI-24672111; Score: 0.56
DE  Interaction: A6NEL2; IntAct: EBI-23696046; Score: 0.56
DE  Interaction: Q15842; IntAct: EBI-24689183; Score: 0.56
DE  Interaction: Q9NQX5; IntAct: EBI-24699630; Score: 0.56
DE  Interaction: Q8N4V1; IntAct: EBI-24709706; Score: 0.56
DE  Interaction: Q7RTU1; IntAct: EBI-23756438; Score: 0.56
DE  Interaction: O60930; IntAct: EBI-23758332; Score: 0.56
DE  Interaction: Q0VD86; IntAct: EBI-24717955; Score: 0.56
DE  Interaction: Q7Z6M4; IntAct: EBI-23772605; Score: 0.56
DE  Interaction: Q9Y320; IntAct: EBI-23795943; Score: 0.56
DE  Interaction: P16157; IntAct: EBI-24733419; Score: 0.56
DE  Interaction: Q9HA82; IntAct: EBI-23800001; Score: 0.56
DE  Interaction: P43628; IntAct: EBI-24742152; Score: 0.56
DE  Interaction: Q9BSJ6; IntAct: EBI-24763001; Score: 0.56
DE  Interaction: Q5JX71; IntAct: EBI-24763501; Score: 0.56
DE  Interaction: Q6IBW4; IntAct: EBI-23853144; Score: 0.56
DE  Interaction: Q86VY9; IntAct: EBI-24778276; Score: 0.56
DE  Interaction: Q8TDT2; IntAct: EBI-25275476; Score: 0.56
DE  Interaction: Q5T7V8; IntAct: EBI-23923221; Score: 0.56
DE  Interaction: Q8IUY3; IntAct: EBI-24390287; Score: 0.56
DE  Interaction: P50221; IntAct: EBI-24397223; Score: 0.56
DE  Interaction: O75031; IntAct: EBI-24417083; Score: 0.56
DE  Interaction: Q9HAQ2; IntAct: EBI-24439983; Score: 0.56
DE  Interaction: Q8TD17; IntAct: EBI-24447341; Score: 0.56
DE  Interaction: Q5SNT2; IntAct: EBI-24476865; Score: 0.68
DE  Interaction: Q96S94; IntAct: EBI-24556880; Score: 0.56
DE  Interaction: Q6P9A3; IntAct: EBI-24557406; Score: 0.56
DE  Interaction: Q9NU63; IntAct: EBI-24580547; Score: 0.56
DE  Interaction: Q5T686; IntAct: EBI-24599743; Score: 0.56
DE  Interaction: P21964; IntAct: EBI-24641360; Score: 0.56
DE  Interaction: Q86UD4; IntAct: EBI-24646904; Score: 0.56
DE  Interaction: Q96PL5; IntAct: EBI-25169259; Score: 0.56
DE  Interaction: Q4KMG9; IntAct: EBI-24747207; Score: 0.56
DE  Interaction: Q68DC2; IntAct: EBI-25195191; Score: 0.56
DE  Interaction: Q9BRJ2; IntAct: EBI-24789200; Score: 0.56
DE  Interaction: Q14500; IntAct: EBI-24790299; Score: 0.56
DE  Interaction: Q7Z7G2; IntAct: EBI-25207978; Score: 0.56
DE  Interaction: Q9H400; IntAct: EBI-24799476; Score: 0.56
DE  Interaction: Q8WWF3; IntAct: EBI-24800633; Score: 0.56
DE  Interaction: Q9UGI6; IntAct: EBI-24807534; Score: 0.56
DE  Interaction: Q86T13; IntAct: EBI-25224374; Score: 0.56
DE  Interaction: Q8WUU8; IntAct: EBI-25273036; Score: 0.56
DE  Interaction: P49910; IntAct: EBI-12696914; Score: 0.56
DE  Interaction: O95292; IntAct: EBI-12698321; Score: 0.56
DE  Interaction: Q9NTW7; IntAct: EBI-12700590; Score: 0.56
DE  Interaction: Q12846; IntAct: EBI-12702158; Score: 0.56
DE  Interaction: P50222; IntAct: EBI-12702328; Score: 0.56
DE  Interaction: Q8N5R6; IntAct: EBI-12702476; Score: 0.56
DE  Interaction: O14829; IntAct: EBI-14024386; Score: 0.35
DE  Interaction: P56180; IntAct: EBI-14025693; Score: 0.57
DE  Interaction: Q6IQ23; IntAct: EBI-16398399; Score: 0.35
DE  Interaction: Q05322; IntAct: EBI-15481401; Score: 0.35
DE  Interaction: P60709; IntAct: EBI-15531451; Score: 0.52
DE  Interaction: P68135; IntAct: EBI-15531470; Score: 0.60
DE  Interaction: Q14684; IntAct: EBI-16686997; Score: 0.35
DE  Interaction: O15155; IntAct: EBI-16788067; Score: 0.27
DE  Interaction: P27824; IntAct: EBI-16788621; Score: 0.27
DE  Interaction: P68431; IntAct: EBI-16793336; Score: 0.27
DE  Interaction: P11279; IntAct: EBI-16794808; Score: 0.27
DE  Interaction: Q9HBL7; IntAct: EBI-16797780; Score: 0.27
DE  Interaction: P62491; IntAct: EBI-16797971; Score: 0.27
DE  Interaction: P20339; IntAct: EBI-16798221; Score: 0.27
DE  Interaction: P51151; IntAct: EBI-16798325; Score: 0.27
DE  Interaction: P62753; IntAct: EBI-16798663; Score: 0.27
DE  Interaction: O43493; IntAct: EBI-16800265; Score: 0.42
DE  Interaction: Q9NS69; IntAct: EBI-16802054; Score: 0.27
DE  Interaction: Q7KZN9; IntAct: EBI-20304305; Score: 0.35
DE  Interaction: P36957; IntAct: EBI-20305285; Score: 0.35
DE  Interaction: P08559; IntAct: EBI-20306509; Score: 0.35
DE  Interaction: P35610; IntAct: EBI-20307233; Score: 0.35
DE  Interaction: P21796; IntAct: EBI-20307902; Score: 0.35
DE  Interaction: Q9HCE5; IntAct: EBI-20595531; Score: 0.35
DE  Interaction: P51957; IntAct: EBI-20721387; Score: 0.35
DE  Interaction: A2A935; IntAct: EBI-21022882; Score: 0.35
DE  Interaction: P14404; IntAct: EBI-21026252; Score: 0.35
DE  Interaction: Q5T7N2; IntAct: EBI-20993270; Score: 0.35
DE  Interaction: P14316; IntAct: EBI-21260627; Score: 0.35
DE  Interaction: Q15077; IntAct: EBI-21262943; Score: 0.35
DE  Interaction: F5H1C8; IntAct: EBI-21264930; Score: 0.35
DE  Interaction: Q03518; IntAct: EBI-21265865; Score: 0.35
DE  Interaction: Q9NQB0; IntAct: EBI-21265942; Score: 0.35
DE  Interaction: Q9H1C4; IntAct: EBI-21266770; Score: 0.35
DE  Interaction: Q9BTV4; IntAct: EBI-22085077; Score: 0.54
DE  Interaction: Q13163; IntAct: EBI-25374437; Score: 0.35
DE  Interaction: Q15311; IntAct: EBI-25375541; Score: 0.35
DE  Interaction: Q92934; IntAct: EBI-25378368; Score: 0.35
DE  Interaction: P19419; IntAct: EBI-25378580; Score: 0.35
DE  Interaction: P0DOF2; IntAct: EBI-25603126; Score: 0.35
DE  Interaction: Q9H9V9; IntAct: EBI-25479633; Score: 0.35
DE  Interaction: Q8N5Y8; IntAct: EBI-25482187; Score: 0.35
DE  Interaction: P69479; IntAct: EBI-25568044; Score: 0.35
DE  Interaction: P0DTC4; IntAct: EBI-25509966; Score: 0.35
DE  Interaction: P0DTC8; IntAct: EBI-25510273; Score: 0.35
DE  Interaction: P0DTD3; IntAct: EBI-25510342; Score: 0.35
DE  Interaction: Q96CS3; IntAct: EBI-25770166; Score: 0.35
DE  Interaction: Q8IWF2; IntAct: EBI-25770736; Score: 0.35
DE  Interaction: Q8NBM4; IntAct: EBI-25771384; Score: 0.35
DE  Interaction: Q5U458; IntAct: EBI-26450034; Score: 0.35
DE  Interaction: O60303; IntAct: EBI-26582514; Score: 0.35
DE  Interaction: P34972; IntAct: EBI-26880846; Score: 0.35
DE  Interaction: P01116; IntAct: EBI-27041844; Score: 0.27
DE  Interaction: P01111; IntAct: EBI-27042293; Score: 0.27
DE  Interaction: F1PAA9; IntAct: EBI-27079701; Score: 0.27
DE  Interaction: A0A0H3NFP4; IntAct: EBI-27055788; Score: 0.27
DE  Interaction: A0A0H3NG92; IntAct: EBI-27055968; Score: 0.27
DE  Interaction: A0A0H3NF08; IntAct: EBI-27055973; Score: 0.27
DE  Interaction: A0A0H3NB75; IntAct: EBI-27055983; Score: 0.27
DE  Interaction: P35226; IntAct: EBI-27108918; Score: 0.35
DE  Interaction: Q99592; IntAct: EBI-27093179; Score: 0.35
DE  Interaction: Q6P5Z2; IntAct: EBI-28941754; Score: 0.35
DE  Interaction: Q86UX6; IntAct: EBI-28942129; Score: 0.35
DE  Interaction: Q99986; IntAct: EBI-28944934; Score: 0.35
DE  Interaction: Q9UJY1; IntAct: EBI-28946841; Score: 0.35
DE  Interaction: Q8NCK7; IntAct: EBI-27103180; Score: 0.35
DE  Interaction: Q93009; IntAct: EBI-30841862; Score: 0.44
DE  Interaction: Q05925; IntAct: EBI-29000369; Score: 0.35
DE  Interaction: P23769; IntAct: EBI-29000495; Score: 0.35
DE  Interaction: P23771; IntAct: EBI-29000509; Score: 0.35
DE  Interaction: Q8TDD2; IntAct: EBI-29000537; Score: 0.35
DE  Interaction: P57682; IntAct: EBI-29000670; Score: 0.35
DE  Interaction: P43694; IntAct: EBI-29011567; Score: 0.35
DE  Interaction: Q9UIH9; IntAct: EBI-29019642; Score: 0.35
DE  Interaction: Q9BXK1; IntAct: EBI-29019783; Score: 0.35
DE  Interaction: O95600; IntAct: EBI-29020196; Score: 0.35
DE  Interaction: P48431; IntAct: EBI-29373058; Score: 0.35
DE  Interaction: P35712; IntAct: EBI-29384845; Score: 0.35
DE  Interaction: P08047; IntAct: EBI-29385496; Score: 0.35
DE  Interaction: P31314; IntAct: EBI-29607649; Score: 0.35
DE  Interaction: O43763; IntAct: EBI-29612789; Score: 0.35
DE  Interaction: O43711; IntAct: EBI-29624592; Score: 0.35
DE  Interaction: P52952; IntAct: EBI-29653951; Score: 0.35
DE  Interaction: Q9Y4X4; IntAct: EBI-29017631; Score: 0.27
DE  Interaction: P21709; IntAct: EBI-32717758; Score: 0.35
DE  Interaction: P29322; IntAct: EBI-32718189; Score: 0.42
DE  Interaction: P22455; IntAct: EBI-32718547; Score: 0.35
DE  Interaction: P35916; IntAct: EBI-32718614; Score: 0.35
DE  Interaction: P08069; IntAct: EBI-32718669; Score: 0.42
DE  Interaction: P06213; IntAct: EBI-32718777; Score: 0.42
DE  Interaction: P08581; IntAct: EBI-32719056; Score: 0.42
DE  Interaction: P04629; IntAct: EBI-32719115; Score: 0.35
DE  Interaction: Q16288; IntAct: EBI-32719212; Score: 0.35
DE  Interaction: Q01974; IntAct: EBI-32719482; Score: 0.42
DE  Interaction: Q6J9G0; IntAct: EBI-32719662; Score: 0.42
DE  Interaction: Q06418; IntAct: EBI-32719716; Score: 0.35
DE  Interaction: Q9UM73; IntAct: EBI-32719830; Score: 0.27
DE  Interaction: P30530; IntAct: EBI-32719959; Score: 0.27
DE  Interaction: P21860; IntAct: EBI-32721529; Score: 0.27
DE  Interaction: P22607; IntAct: EBI-32721979; Score: 0.27
DE  Interaction: P17948; IntAct: EBI-32722433; Score: 0.27
DE  Interaction: P36888; IntAct: EBI-32722567; Score: 0.27
DE  Interaction: P14616; IntAct: EBI-32723232; Score: 0.27
DE  Interaction: P35968; IntAct: EBI-32723270; Score: 0.27
DE  Interaction: Q8IWU2; IntAct: EBI-32723604; Score: 0.27
DE  Interaction: Q12866; IntAct: EBI-32723870; Score: 0.27
DE  Interaction: O15146; IntAct: EBI-32724025; Score: 0.27
DE  Interaction: P07949; IntAct: EBI-32725031; Score: 0.27
DE  Interaction: P08922; IntAct: EBI-32731758; Score: 0.27
DE  Interaction: Q02763; IntAct: EBI-32732012; Score: 0.35
DE  Interaction: Q8N612; IntAct: EBI-34574737; Score: 0.27
DE  Interaction: Q5W0V3; IntAct: EBI-34574999; Score: 0.27
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0005783;
GO  GO:0016021;
GO  GO:0016020;
GO  GO:0005874;
GO  GO:0005635;
GO  GO:0005637;
GO  GO:0031965;
GO  GO:0005640;
GO  GO:0005654;
GO  GO:0005819;
GO  GO:0003779;
GO  GO:0048487;
GO  GO:0045296;
GO  GO:0071363;
GO  GO:0006936;
GO  GO:0007517;
GO  GO:0090090;
GO  GO:0048147;
GO  GO:0071763;
GO  GO:0046827;
GO  GO:0060828;
GO  GO:0035914;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MDNYADLSDTELTTLLRRYNIPHGPVVGSTRRLYEKKIFEYETQRRRLSPPSSSAASSYSFSDLNSTRGDADMYDLPKKE
SQ  DALLYQSKGYNDDYYEESYFTTRTYGEPESAGPSRAVRQSVTSFPDADAFHHQVHDDDLLSSSEEECKDRERPMYGRDSA
SQ  YQSITHYRPVSASRSSLDLSYYPTSSSTSFMSSSSSSSSWLTRRAIRPENRAPGAGLGQDRQVPLWGQLLLFLVFVIVLF
SQ  FIYHFMQAEEGNPF
//