ID  P62826;
PN  GTP-binding nuclear protein Ran;
GN  RAN;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus {ECO:0000269|PubMed:10679025, ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:18617507, ECO:0000269|PubMed:1961752, ECO:0000269|PubMed:19753112, ECO:0000269|PubMed:31075303, ECO:0000269|PubMed:8421051, ECO:0000269|PubMed:8896452, ECO:0000269|PubMed:9351834, ECO:0000269|PubMed:9822603}. Nucleus envelope {ECO:0000269|PubMed:8896452, ECO:0000269|PubMed:9822603}. Cytoplasm, cytosol {ECO:0000269|PubMed:18617507, ECO:0000269|PubMed:8276887}. Cytoplasm {ECO:0000269|PubMed:10679025, ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:9822603}. Melanosome {ECO:0000269|PubMed:17081065}. Note=Predominantly nuclear during interphase (PubMed:8421051, PubMed:12194828, PubMed:10679025). Becomes dispersed throughout the cytoplasm during mitosis (PubMed:8421051, PubMed:12194828). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). {ECO:0000269|PubMed:10679025, ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:17081065, ECO:0000269|PubMed:8421051}.
DR  UNIPROT: P62826;
DR  UNIPROT: A8K3Z8;
DR  UNIPROT: P17080;
DR  UNIPROT: P28746;
DR  UNIPROT: P28747;
DR  UNIPROT: Q6IPB2;
DR  UNIPROT: Q86V08;
DR  UNIPROT: Q8NI90;
DR  UNIPROT: Q9CSP3;
DR  UNIPROT: Q9CWI7;
DR  UNIPROT: Q9CZA2;
DR  UNIPROT: Q9UDJ5;
DR  UNIPROT: Q9UEU9;
DR  PDB: 1I2M;
DR  PDB: 1IBR;
DR  PDB: 1K5D;
DR  PDB: 1K5G;
DR  PDB: 1QBK;
DR  PDB: 1RRP;
DR  PDB: 2MMC;
DR  PDB: 2MMG;
DR  PDB: 2N1B;
DR  PDB: 3CH5;
DR  PDB: 3EA5;
DR  PDB: 3GJ0;
DR  PDB: 3GJ3;
DR  PDB: 3GJ4;
DR  PDB: 3GJ5;
DR  PDB: 3GJ6;
DR  PDB: 3GJ7;
DR  PDB: 3GJ8;
DR  PDB: 3GJX;
DR  PDB: 3NBY;
DR  PDB: 3NBZ;
DR  PDB: 3NC0;
DR  PDB: 3NC1;
DR  PDB: 3ZJY;
DR  PDB: 4C0Q;
DR  PDB: 4GMX;
DR  PDB: 4GPT;
DR  PDB: 4HAT;
DR  PDB: 4HAU;
DR  PDB: 4HAV;
DR  PDB: 4HAW;
DR  PDB: 4HAX;
DR  PDB: 4HAY;
DR  PDB: 4HAZ;
DR  PDB: 4HB0;
DR  PDB: 4HB2;
DR  PDB: 4HB3;
DR  PDB: 4HB4;
DR  PDB: 4OL0;
DR  PDB: 4WVF;
DR  PDB: 5CIQ;
DR  PDB: 5CIT;
DR  PDB: 5CIW;
DR  PDB: 5CJ2;
DR  PDB: 5CLL;
DR  PDB: 5CLQ;
DR  PDB: 5DH9;
DR  PDB: 5DHA;
DR  PDB: 5DHF;
DR  PDB: 5DI9;
DR  PDB: 5DIF;
DR  PDB: 5DIS;
DR  PDB: 5DLQ;
DR  PDB: 5FYQ;
DR  PDB: 5JLJ;
DR  PDB: 5UWH;
DR  PDB: 5UWI;
DR  PDB: 5UWJ;
DR  PDB: 5UWO;
DR  PDB: 5UWP;
DR  PDB: 5UWQ;
DR  PDB: 5UWR;
DR  PDB: 5UWS;
DR  PDB: 5UWT;
DR  PDB: 5UWU;
DR  PDB: 5UWW;
DR  PDB: 5YRO;
DR  PDB: 5YST;
DR  PDB: 5YSU;
DR  PDB: 5YTB;
DR  PDB: 5ZPU;
DR  PDB: 6A38;
DR  PDB: 6A3A;
DR  PDB: 6A3B;
DR  PDB: 6A3C;
DR  PDB: 6A3E;
DR  PDB: 6CIT;
DR  PDB: 6KFT;
DR  PDB: 6LQ9;
DR  PDB: 6M60;
DR  PDB: 6M6X;
DR  PDB: 6Q82;
DR  PDB: 6Q84;
DR  PDB: 6TVO;
DR  PDB: 6X2M;
DR  PDB: 6X2O;
DR  PDB: 6X2P;
DR  PDB: 6X2R;
DR  PDB: 6X2S;
DR  PDB: 6X2U;
DR  PDB: 6X2V;
DR  PDB: 6X2W;
DR  PDB: 6X2X;
DR  PDB: 6X2Y;
DR  PDB: 6XJP;
DR  PDB: 6XJR;
DR  PDB: 6XJS;
DR  PDB: 6XJT;
DR  PDB: 6XJU;
DR  PDB: 7B51;
DR  PDB: 7CND;
DR  PDB: 7DBG;
DR  PDB: 7L5E;
DR  Pfam: PF00071;
DR  PROSITE: PS51418;
DR  OMIM: 601179;
DR  DisGeNET: 5901;
DE  Function: GTPase involved in nucleocytoplasmic transport, participating both to the import and the export from the nucleus of proteins and RNAs (PubMed:10400640, PubMed:8276887, PubMed:8896452, PubMed:8636225, PubMed:8692944, PubMed:9351834, PubMed:9428644, PubMed:9822603, PubMed:17209048, PubMed:26272610, PubMed:27306458). Switches between a cytoplasmic GDP- and a nuclear GTP-bound state by nucleotide exchange and GTP hydrolysis (PubMed:7819259, PubMed:8896452, PubMed:8636225, PubMed:8692944, PubMed:9351834, PubMed:9428644, PubMed:9822603, PubMed:29040603, PubMed:11336674, PubMed:26272610). Nuclear import receptors such as importin beta bind their substrates only in the absence of GTP-bound RAN and release them upon direct interaction with GTP-bound RAN, while export receptors behave in the opposite way. Thereby, RAN controls cargo loading and release by transport receptors in the proper compartment and ensures the directionality of the transport (PubMed:8896452, PubMed:9351834, PubMed:9428644). Interaction with RANBP1 induces a conformation change in the complex formed by XPO1 and RAN that triggers the release of the nuclear export signal of cargo proteins (PubMed:20485264). RAN (GTP-bound form) triggers microtubule assembly at mitotic chromosomes and is required for normal mitotic spindle assembly and chromosome segregation (PubMed:10408446, PubMed:29040603). Required for normal progress through mitosis (PubMed:8421051, PubMed:12194828, PubMed:29040603). The complex with BIRC5/survivin plays a role in mitotic spindle formation by serving as a physical scaffold to help deliver the RAN effector molecule TPX2 to microtubules (PubMed:18591255). Acts as a negative regulator of the kinase activity of VRK1 and VRK2 (PubMed:18617507). Enhances AR- mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases (PubMed:10400640). {ECO:0000269|PubMed:10400640, ECO:0000269|PubMed:10408446, ECO:0000269|PubMed:11336674, ECO:0000269|PubMed:12194828, ECO:0000269|PubMed:17209048, ECO:0000269|PubMed:18591255, ECO:0000269|PubMed:18617507, ECO:0000269|PubMed:20485264, ECO:0000269|PubMed:26272610, ECO:0000269|PubMed:27306458, ECO:0000269|PubMed:29040603, ECO:0000269|PubMed:7819259, ECO:0000269|PubMed:8276887, ECO:0000269|PubMed:8421051, ECO:0000269|PubMed:8636225, ECO:0000269|PubMed:8692944, ECO:0000269|PubMed:8896452, ECO:0000269|PubMed:9351834, ECO:0000269|PubMed:9428644, ECO:0000269|PubMed:9822603, ECO:0000305|PubMed:26272610}.
DE  Reference Proteome: Yes;
DE  Interaction: A6NFY4; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: O14524; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: O60356; IntAct: EBI-15569882; Score: 0.37
DE  Interaction: O95271; IntAct: EBI-9692184; Score: 0.40
DE  Interaction: P35658; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: P37198; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: P41391; IntAct: EBI-1032926; Score: 0.40
DE  Interaction: P46060; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: P49790; IntAct: EBI-9688194; Score: 0.64
DE  Interaction: P49791; IntAct: EBI-15714795; Score: 0.67
DE  Interaction: P49792; IntAct: EBI-3933494; Score: 0.76
DE  Interaction: P52297; IntAct: EBI-286729; Score: 0.35
DE  Interaction: P57740; IntAct: EBI-11160436; Score: 0.35
DE  Interaction: P61970; IntAct: EBI-9688194; Score: 0.81
DE  Interaction: O42480; IntAct: EBI-286729; Score: 0.35
DE  Interaction: Q6GMY9; IntAct: EBI-286729; Score: 0.35
DE  Interaction: P52292; IntAct: EBI-13942323; Score: 0.40
DE  Interaction: Q92973; IntAct: EBI-1027757; Score: 0.44
DE  Interaction: P60709; IntAct: EBI-353790; Score: 0.40
DE  Interaction: P46527; IntAct: EBI-591758; Score: 0.40
DE  Interaction: Q9P2H0; IntAct: EBI-733094; Score: 0.00
DE  Interaction: P07196; IntAct: EBI-737516; Score: 0.00
DE  Interaction: P03254; IntAct: EBI-8626155; Score: 0.59
DE  Interaction: P03129; IntAct: EBI-8626194; Score: 0.44
DE  Interaction: P43487; IntAct: EBI-8626224; Score: 0.61
DE  Interaction: P03070; IntAct: EBI-8626209; Score: 0.44
DE  Interaction: P03255; IntAct: EBI-8544308; Score: 0.40
DE  Interaction: Q9H6Z4; IntAct: EBI-992712; Score: 0.40
DE  Interaction: P18754; IntAct: EBI-1031180; Score: 0.88
DE  Interaction: Q00005; IntAct: EBI-2211497; Score: 0.35
DE  Interaction: Q99986; IntAct: EBI-1795237; Score: 0.60
DE  Interaction: Q86Y07; IntAct: EBI-1795483; Score: 0.40
DE  Interaction: Q8IV63; IntAct: EBI-1795543; Score: 0.40
DE  Interaction: O15264; IntAct: EBI-2255044; Score: 0.35
DE  Interaction: Q8IY92; IntAct: EBI-2371120; Score: 0.35
DE  Interaction: Q9BQ83; IntAct: EBI-2372444; Score: 0.35
DE  Interaction: Q9ERU9; IntAct: EBI-2555617; Score: 0.56
DE  Interaction: Q9JMK2; IntAct: EBI-2558429; Score: 0.40
DE  Interaction: Q8CEC0; IntAct: EBI-2562665; Score: 0.40
DE  Interaction: Q8VD62; IntAct: EBI-2562857; Score: 0.40
DE  Interaction: Q6ZQH8; IntAct: EBI-2563113; Score: 0.40
DE  Interaction: Q60610; IntAct: EBI-7567120; Score: 0.44
DE  Interaction: Q6ZPF3; IntAct: EBI-7567337; Score: 0.44
DE  Interaction: P43354; IntAct: EBI-2681788; Score: 0.00
DE  Interaction: Q15796; IntAct: EBI-2684985; Score: 0.00
DE  Interaction: O76187; IntAct: EBI-2905901; Score: 0.40
DE  Interaction: P18124; IntAct: EBI-8297497; Score: 0.40
DE  Interaction: Q9HAV4; IntAct: EBI-2938145; Score: 0.40
DE  Interaction: O94829; IntAct: EBI-8534600; Score: 0.73
DE  Interaction: Q99666; IntAct: EBI-3940764; Score: 0.55
DE  Interaction: Q5TAQ9; IntAct: EBI-7817945; Score: 0.27
DE  Interaction: O95758; IntAct: EBI-7850130; Score: 0.35
DE  Interaction: P19320; IntAct: EBI-6189915; Score: 0.35
DE  Interaction: P10209; IntAct: EBI-6509326; Score: 0.37
DE  Interaction: P47813; IntAct: EBI-9207355; Score: 0.59
DE  Interaction: O15392; IntAct: EBI-9548404; Score: 0.63
DE  Interaction: P42771; IntAct: EBI-9691810; Score: 0.46
DE  Interaction: Q13625; IntAct: EBI-9692277; Score: 0.64
DE  Interaction: Q8WUF5; IntAct: EBI-9692274; Score: 0.65
DE  Interaction: Q8WVL7; IntAct: EBI-9691643; Score: 0.40
DE  Interaction: Q91974; IntAct: EBI-9691221; Score: 0.40
DE  Interaction: O14974; IntAct: EBI-9692208; Score: 0.40
DE  Interaction: Q9HBA0; IntAct: EBI-9692161; Score: 0.40
DE  Interaction: Q06547; IntAct: EBI-25889543; Score: 0.56
DE  Interaction: Q96KQ4; IntAct: EBI-9692121; Score: 0.40
DE  Interaction: P25963; IntAct: EBI-9692133; Score: 0.40
DE  Interaction: O14920; IntAct: EBI-10103342; Score: 0.35
DE  Interaction: Q13418; IntAct: EBI-10103376; Score: 0.35
DE  Interaction: P29597; IntAct: EBI-10104620; Score: 0.35
DE  Interaction: Q96FW1; IntAct: EBI-10770198; Score: 0.35
DE  Interaction: P19838; IntAct: EBI-11322719; Score: 0.35
DE  Interaction: P05412; IntAct: EBI-11323169; Score: 0.35
DE  Interaction: Q6PFD9; IntAct: EBI-10994876; Score: 0.35
DE  Interaction: Q8BH74; IntAct: EBI-10997196; Score: 0.35
DE  Interaction: Q96L14; IntAct: EBI-11022408; Score: 0.35
DE  Interaction: Q8VE37; IntAct: EBI-11043815; Score: 0.35
DE  Interaction: P63280; IntAct: EBI-11044140; Score: 0.35
DE  Interaction: P34022; IntAct: EBI-11080066; Score: 0.35
DE  Interaction: Q8CAQ8; IntAct: EBI-11096643; Score: 0.35
DE  Interaction: Q9Y496; IntAct: EBI-11097996; Score: 0.35
DE  Interaction: P63279; IntAct: EBI-11105225; Score: 0.53
DE  Interaction: P26367; IntAct: EBI-11107399; Score: 0.35
DE  Interaction: Q14974; IntAct: EBI-11115566; Score: 0.53
DE  Interaction: O43896; IntAct: EBI-11140183; Score: 0.35
DE  Interaction: Q3V6T2; IntAct: EBI-11141559; Score: 0.35
DE  Interaction: Q9UBX2; IntAct: EBI-11614356; Score: 0.35
DE  Interaction: O43592; IntAct: EBI-24355918; Score: 0.56
DE  Interaction: O14787; IntAct: EBI-24386976; Score: 0.56
DE  Interaction: Q9UIA9; IntAct: EBI-24411618; Score: 0.56
DE  Interaction: Q9HD47; IntAct: EBI-25889861; Score: 0.56
DE  Interaction: Q9H9L7; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: Q96P70; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: Q70UQ0; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: Q69YH5; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: P0DJD1; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: Q15398; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: O14715; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: O00629; IntAct: EBI-21557447; Score: 0.35
DE  Interaction: Q53H80; IntAct: EBI-21567350; Score: 0.35
DE  Interaction: P54645; IntAct: EBI-16361875; Score: 0.35
DE  Interaction: P80386; IntAct: EBI-16362252; Score: 0.35
DE  Interaction: P70168; IntAct: EBI-15732723; Score: 0.44
DE  Interaction: P61925; IntAct: EBI-15886863; Score: 0.52
DE  Interaction: Q6P5F9; IntAct: EBI-15887025; Score: 0.68
DE  Interaction: O95149; IntAct: EBI-16064299; Score: 0.40
DE  Interaction: Q01968; IntAct: EBI-16412116; Score: 0.35
DE  Interaction: Q9EPK7; IntAct: EBI-17168930; Score: 0.35
DE  Interaction: Q07960; IntAct: EBI-17172410; Score: 0.40
DE  Interaction: Q9D3W4; IntAct: EBI-17172527; Score: 0.40
DE  Interaction: Q9CWR2; IntAct: EBI-17172552; Score: 0.40
DE  Interaction: O35381; IntAct: EBI-17172576; Score: 0.40
DE  Interaction: Q61074; IntAct: EBI-17172591; Score: 0.40
DE  Interaction: Q9EQU5; IntAct: EBI-17172606; Score: 0.40
DE  Interaction: O09012; IntAct: EBI-17172621; Score: 0.40
DE  Interaction: Q8VE09; IntAct: EBI-17172636; Score: 0.40
DE  Interaction: Q8VCE2; IntAct: EBI-17172666; Score: 0.40
DE  Interaction: Q9Z0P7; IntAct: EBI-17172681; Score: 0.40
DE  Interaction: P97822; IntAct: EBI-17172705; Score: 0.40
DE  Interaction: Q9Z1K5; IntAct: EBI-17172733; Score: 0.40
DE  Interaction: P58043; IntAct: EBI-17172748; Score: 0.40
DE  Interaction: Q8BP48; IntAct: EBI-17172763; Score: 0.40
DE  Interaction: Q60737; IntAct: EBI-17172823; Score: 0.40
DE  Interaction: P15659; IntAct: EBI-25769098; Score: 0.37
DE  Interaction: P03430; IntAct: EBI-25769362; Score: 0.37
DE  Interaction: P03427; IntAct: EBI-25769803; Score: 0.37
DE  Interaction: Q92731; IntAct: EBI-20764883; Score: 0.35
DE  Interaction: O75391; IntAct: EBI-20907624; Score: 0.40
DE  Interaction: Q93073; IntAct: EBI-20910936; Score: 0.40
DE  Interaction: O75054; IntAct: EBI-20912478; Score: 0.40
DE  Interaction: Q9NRL2; IntAct: EBI-20921060; Score: 0.40
DE  Interaction: P16401; IntAct: EBI-20928448; Score: 0.40
DE  Interaction: Q93079; IntAct: EBI-20929824; Score: 0.40
DE  Interaction: Q16695; IntAct: EBI-20929816; Score: 0.40
DE  Interaction: Q9HAP2; IntAct: EBI-20933308; Score: 0.40
DE  Interaction: P62805; IntAct: EBI-20933064; Score: 0.40
DE  Interaction: Q9BXS9; IntAct: EBI-20936124; Score: 0.40
DE  Interaction: A2A935; IntAct: EBI-21022882; Score: 0.35
DE  Interaction: P14404; IntAct: EBI-21026252; Score: 0.35
DE  Interaction: Q5T7N2; IntAct: EBI-20993270; Score: 0.35
DE  Interaction: P13569; IntAct: EBI-25416349; Score: 0.53
DE  Interaction: Q9UQC2; IntAct: EBI-25384304; Score: 0.35
DE  Interaction: P63000; IntAct: EBI-25387902; Score: 0.35
DE  Interaction: P06239; IntAct: EBI-25394571; Score: 0.35
DE  Interaction: P0DOF2; IntAct: EBI-25603126; Score: 0.35
DE  Interaction: P69479; IntAct: EBI-25568051; Score: 0.35
DE  Interaction: Q5EP34; IntAct: EBI-25772822; Score: 0.35
DE  Interaction: Q92797; IntAct: EBI-25889687; Score: 0.56
DE  Interaction: O43829; IntAct: EBI-25889679; Score: 0.56
DE  Interaction: P49459; IntAct: EBI-25889671; Score: 0.56
DE  Interaction: Q12888; IntAct: EBI-25889663; Score: 0.56
DE  Interaction: P54274; IntAct: EBI-25889655; Score: 0.56
DE  Interaction: O60927; IntAct: EBI-25889647; Score: 0.56
DE  Interaction: P22307; IntAct: EBI-25889639; Score: 0.56
DE  Interaction: P62701; IntAct: EBI-25889631; Score: 0.56
DE  Interaction: Q15382; IntAct: EBI-25889623; Score: 0.56
DE  Interaction: P47804; IntAct: EBI-25889615; Score: 0.56
DE  Interaction: Q04206; IntAct: EBI-25889607; Score: 0.56
DE  Interaction: Q09028; IntAct: EBI-25889599; Score: 0.56
DE  Interaction: Q07869; IntAct: EBI-25889591; Score: 0.56
DE  Interaction: P36954; IntAct: EBI-25889583; Score: 0.56
DE  Interaction: O15534; IntAct: EBI-25889575; Score: 0.56
DE  Interaction: P36639; IntAct: EBI-25889567; Score: 0.56
DE  Interaction: P27338; IntAct: EBI-25889559; Score: 0.56
DE  Interaction: Q9NRZ9; IntAct: EBI-25889551; Score: 0.56
DE  Interaction: P06241; IntAct: EBI-25889535; Score: 0.56
DE  Interaction: P35222; IntAct: EBI-25889527; Score: 0.56
DE  Interaction: Q86WV5; IntAct: EBI-25889519; Score: 0.56
DE  Interaction: P20807; IntAct: EBI-25889511; Score: 0.56
DE  Interaction: P17655; IntAct: EBI-25889503; Score: 0.56
DE  Interaction: A0A384MDV8; IntAct: EBI-25889495; Score: 0.56
DE  Interaction: P06276; IntAct: EBI-25889487; Score: 0.56
DE  Interaction: Q14032; IntAct: EBI-25889479; Score: 0.56
DE  Interaction: P36406; IntAct: EBI-25889471; Score: 0.56
DE  Interaction: P09525; IntAct: EBI-25889463; Score: 0.56
DE  Interaction: Q9Y3D0; IntAct: EBI-25889937; Score: 0.56
DE  Interaction: Q7Z3B4; IntAct: EBI-25889945; Score: 0.56
DE  Interaction: Q66PJ3; IntAct: EBI-25889919; Score: 0.56
DE  Interaction: Q96IZ7; IntAct: EBI-25889911; Score: 0.56
DE  Interaction: Q9UK76; IntAct: EBI-25889903; Score: 0.56
DE  Interaction: P0DPB6; IntAct: EBI-25889895; Score: 0.56
DE  Interaction: Q49AJ0; IntAct: EBI-25889885; Score: 0.56
DE  Interaction: Q9Y303; IntAct: EBI-25889877; Score: 0.56
DE  Interaction: Q9NNX6; IntAct: EBI-25889869; Score: 0.56
DE  Interaction: Q9H0W9; IntAct: EBI-25889853; Score: 0.56
DE  Interaction: Q9UIK5; IntAct: EBI-25889845; Score: 0.56
DE  Interaction: Q14181; IntAct: EBI-25889837; Score: 0.56
DE  Interaction: Q86US8; IntAct: EBI-25889829; Score: 0.56
DE  Interaction: Q13573; IntAct: EBI-25889821; Score: 0.56
DE  Interaction: O00472; IntAct: EBI-25889813; Score: 0.56
DE  Interaction: Q96H20; IntAct: EBI-25889805; Score: 0.56
DE  Interaction: O95070; IntAct: EBI-25889797; Score: 0.56
DE  Interaction: Q9Y614; IntAct: EBI-25889789; Score: 0.56
DE  Interaction: O60506; IntAct: EBI-25889781; Score: 0.56
DE  Interaction: Q13901; IntAct: EBI-25889773; Score: 0.56
DE  Interaction: Q8N5U6; IntAct: EBI-25889765; Score: 0.56
DE  Interaction: Q96EY1; IntAct: EBI-25889755; Score: 0.56
DE  Interaction: Q86V28; IntAct: EBI-25889739; Score: 0.56
DE  Interaction: O95674; IntAct: EBI-25889731; Score: 0.56
DE  Interaction: P0C870; IntAct: EBI-25889723; Score: 0.56
DE  Interaction: O15273; IntAct: EBI-25889715; Score: 0.56
DE  Interaction: O00257; IntAct: EBI-25889707; Score: 0.56
DE  Interaction: Q92782; IntAct: EBI-25889697; Score: 0.56
DE  Interaction: Q9NTN9; IntAct: EBI-25890047; Score: 0.56
DE  Interaction: Q5W111; IntAct: EBI-25890039; Score: 0.56
DE  Interaction: Q05CR2; IntAct: EBI-25890031; Score: 0.56
DE  Interaction: Q6GQQ9; IntAct: EBI-25890021; Score: 0.56
DE  Interaction: Q9BPU6; IntAct: EBI-25890013; Score: 0.56
DE  Interaction: Q8IYM2; IntAct: EBI-25890005; Score: 0.56
DE  Interaction: Q9NX94; IntAct: EBI-25889997; Score: 0.56
DE  Interaction: Q8TBB5; IntAct: EBI-25889989; Score: 0.56
DE  Interaction: Q9UKG9; IntAct: EBI-25889981; Score: 0.56
DE  Interaction: Q9UGL9; IntAct: EBI-25889973; Score: 0.56
DE  Interaction: Q6UY14; IntAct: EBI-25889963; Score: 0.56
DE  Interaction: Q9NSI6; IntAct: EBI-25889955; Score: 0.56
DE  Interaction: Q9P1Q0; IntAct: EBI-25889929; Score: 0.56
DE  Interaction: Q53FD0; IntAct: EBI-25890107; Score: 0.56
DE  Interaction: Q6N063; IntAct: EBI-25890097; Score: 0.56
DE  Interaction: Q9BUL5; IntAct: EBI-25890089; Score: 0.56
DE  Interaction: Q9H2C1; IntAct: EBI-25890057; Score: 0.56
DE  Interaction: Q96BR5; IntAct: EBI-25890073; Score: 0.56
DE  Interaction: A0A0A0MR05; IntAct: EBI-25890065; Score: 0.56
DE  Interaction: Q9BQA1; IntAct: EBI-25890081; Score: 0.56
DE  Interaction: Q9H0Y0; IntAct: EBI-25890197; Score: 0.56
DE  Interaction: Q9C004; IntAct: EBI-25890181; Score: 0.56
DE  Interaction: Q8N5Z5; IntAct: EBI-25890115; Score: 0.56
DE  Interaction: Q96BD6; IntAct: EBI-25890157; Score: 0.56
DE  Interaction: Q3SXR2; IntAct: EBI-25890149; Score: 0.56
DE  Interaction: Q9H8K7; IntAct: EBI-25890141; Score: 0.56
DE  Interaction: B7Z3E8; IntAct: EBI-25890133; Score: 0.56
DE  Interaction: Q6IN84; IntAct: EBI-25890125; Score: 0.56
DE  Interaction: Q16609; IntAct: EBI-25890165; Score: 0.56
DE  Interaction: Q494V2; IntAct: EBI-25890475; Score: 0.56
DE  Interaction: Q8IWT0; IntAct: EBI-25890451; Score: 0.56
DE  Interaction: Q66K80; IntAct: EBI-25890443; Score: 0.56
DE  Interaction: Q3SX64; IntAct: EBI-25890435; Score: 0.56
DE  Interaction: Q8N0U6; IntAct: EBI-25890427; Score: 0.56
DE  Interaction: Q496A3; IntAct: EBI-25890419; Score: 0.56
DE  Interaction: Q96Q83; IntAct: EBI-25890411; Score: 0.56
DE  Interaction: Q658K8; IntAct: EBI-25890403; Score: 0.56
DE  Interaction: A6NJ78; IntAct: EBI-25890393; Score: 0.56
DE  Interaction: Q8IZU1; IntAct: EBI-25890385; Score: 0.56
DE  Interaction: Q9H2U1; IntAct: EBI-25890377; Score: 0.56
DE  Interaction: Q6PJW8; IntAct: EBI-25890369; Score: 0.56
DE  Interaction: Q6DHV7; IntAct: EBI-25890361; Score: 0.56
DE  Interaction: Q96MA6; IntAct: EBI-25890353; Score: 0.56
DE  Interaction: Q6ZNL6; IntAct: EBI-25890343; Score: 0.56
DE  Interaction: Q96LX8; IntAct: EBI-25890335; Score: 0.56
DE  Interaction: Q86WT6; IntAct: EBI-25890327; Score: 0.56
DE  Interaction: Q6ZMI0; IntAct: EBI-25890319; Score: 0.56
DE  Interaction: Q8N1A0; IntAct: EBI-25890311; Score: 0.56
DE  Interaction: Q6XD76; IntAct: EBI-25890303; Score: 0.56
DE  Interaction: Q96A09; IntAct: EBI-25890295; Score: 0.56
DE  Interaction: Q8IYG6; IntAct: EBI-25890285; Score: 0.56
DE  Interaction: Q96Q07; IntAct: EBI-25890277; Score: 0.56
DE  Interaction: Q53NU3; IntAct: EBI-25890269; Score: 0.56
DE  Interaction: Q9BT25; IntAct: EBI-25890261; Score: 0.56
DE  Interaction: Q8WUX9; IntAct: EBI-25890253; Score: 0.56
DE  Interaction: Q8WUD1; IntAct: EBI-25890237; Score: 0.56
DE  Interaction: Q49A26; IntAct: EBI-25890229; Score: 0.56
DE  Interaction: Q6NXT2; IntAct: EBI-25890517; Score: 0.56
DE  Interaction: Q8WW27; IntAct: EBI-25890509; Score: 0.56
DE  Interaction: Q3KNS6; IntAct: EBI-25890483; Score: 0.56
DE  Interaction: A2RUH7; IntAct: EBI-25890459; Score: 0.56
DE  Interaction: Q5JTY5; IntAct: EBI-25890525; Score: 0.56
DE  Interaction: P09936; IntAct: EBI-25894615; Score: 0.56
DE  Interaction: Q7Z699; IntAct: EBI-25930873; Score: 0.56
DE  Interaction: P42858; IntAct: EBI-25952651; Score: 0.56
DE  Interaction: P37840; IntAct: EBI-25983264; Score: 0.56
DE  Interaction: Q09161; IntAct: EBI-26398700; Score: 0.35
DE  Interaction: P10636; IntAct: EBI-26374389; Score: 0.27
DE  Interaction: Q99608; IntAct: EBI-26955247; Score: 0.27
DE  Interaction: P06401; IntAct: EBI-26871590; Score: 0.35
DE  Interaction: F1PAA9; IntAct: EBI-27079701; Score: 0.27
DE  Interaction: P35226; IntAct: EBI-27109494; Score: 0.35
DE  Interaction: Q92630; IntAct: EBI-28952196; Score: 0.27
GO  GO:0005814;
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0070062;
GO  GO:0042470;
GO  GO:0016020;
GO  GO:0030496;
GO  GO:0005635;
GO  GO:0005643;
GO  GO:0005730;
GO  GO:0005654;
GO  GO:0005634;
GO  GO:0032991;
GO  GO:0055037;
GO  GO:0042565;
GO  GO:0045296;
GO  GO:0003682;
GO  GO:0019003;
GO  GO:0005525;
GO  GO:0003924;
GO  GO:0000287;
GO  GO:0046982;
GO  GO:0003723;
GO  GO:0030036;
GO  GO:0051301;
GO  GO:0006259;
GO  GO:0046039;
GO  GO:0000278;
GO  GO:0000070;
GO  GO:0007052;
GO  GO:0032092;
GO  GO:0042307;
GO  GO:0035281;
GO  GO:0006611;
GO  GO:0006606;
GO  GO:1902570;
GO  GO:0000055;
GO  GO:0000056;
GO  GO:0000054;
GO  GO:0061015;
GO  GO:0016032;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAAQGEPQVQFKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQEKFGGLRDGYY
SQ  IQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFHRKKNLQYYDISAKSNYNFEKP
SQ  FLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTALPDEDDDL
//