ID  P70581;
PN  Nucleoporin p58/p45;
GN  Nup58;
OS  10116;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0185;
SL  Comments: Nucleus, nuclear pore complex {ECO:0000269|PubMed:8707840}. Nucleus membrane {ECO:0000269|PubMed:8707840}; Peripheral membrane protein {ECO:0000269|PubMed:8707840}; Cytoplasmic side {ECO:0000269|PubMed:8707840}. Nucleus membrane {ECO:0000269|PubMed:8707840}; Peripheral membrane protein {ECO:0000269|PubMed:8707840}; Nucleoplasmic side {ECO:0000269|PubMed:8707840}. Note=Biased towards cytoplasmic side. Central region of the nuclear pore complex, within the transporter.
DR  UNIPROT: P70581;
DR  UNIPROT: Q9JHE1;
DR  UNIPROT: Q9QWK7;
DR  UNIPROT: Q9Z2W7;
DR  PDB: 2OSZ;
DR  PDB: 3T98;
DE  Function: Component of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane. {ECO:0000269|PubMed:8707840}.
DE  Reference Proteome: Yes;
GO  GO:0005635;
GO  GO:0031965;
GO  GO:0005643;
GO  GO:0032991;
GO  GO:0042802;
GO  GO:0008139;
GO  GO:0044877;
GO  GO:0017056;
GO  GO:0051028;
GO  GO:0006913;
GO  GO:0015031;
GO  GO:0042306;
TP  Membrane Topology: Peripheral; Source: UniProt - Experimental Evidence {ECO:0000269|PubMed:8707840};
SQ  MATGFSFGSGTLGSTTVAPGGTGTGSGFSFGASSTPSVGLNFGTLGSSATPASTSTSASGFGTGLFGSKPGTGFTLGGTS
SQ  AGTTATTSASTTGFSLGFSKPAASATPFALPVTSTTASGLTLSSALTSAPAASTGFTLNNLGATPATTTAASTGLSLGGA
SQ  LAGLGGSLFQSGNTATSGLGQNALSLSLGTATPTSAASSEGLGGIDFSTSSDKKSDKTGTRPEDSKALKDENLPPVICQD
SQ  VENLQKFVKEQKQVQEEISRMSSKAMLKVQEDIKALKQLLSLAASGLQRNTLNIDKLKLETAQELKNAEIALRTQKTPPG
SQ  LQHENTAPADYFRVLVQQFEVQLQQYRQQIEELENHLATQANNSHITPQDLSMAMQKIYQTFVALAAQLQSIHENVKVLK
SQ  EQYLSYRKMFLGDAGDVFEARRTEAKKWQNAPRVTTGPTPFSTMPNAAAVAMAATLTQQQQPATGPQPSLGVSFGTPFGS
SQ  GIGTGLQSSGLGSSNLGGFGTSSGFGCGTTGASTFGFGTTDKPSGSLSAGFGSSSTSGFNFSNPGITASAGLTFGVSNPA
SQ  SAGFGTGGQLLQLKRPPAGNKRGKR
//