ID  Q03281;
PN  Inner nuclear membrane protein HEH2;
GN  HEH2;
OS  559292;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16929305}; Single-pass membrane protein {ECO:0000269|PubMed:14562095, ECO:0000269|PubMed:16929305}. Note=Targeting to the inner nuclear membrane requires the SRP1 and KAP95 karyopherins and the Ran cycle.
DR  UNIPROT: Q03281;
DR  UNIPROT: D6VT82;
DR  PDB: 4PVZ;
DR  Pfam: PF12949;
DR  Pfam: PF09402;
DE  Function: 
DE  Reference Proteome: Yes;
DE  Interaction: P38181; IntAct: EBI-10052697; Score: 0.44
DE  Interaction: P39929; IntAct: EBI-10052667; Score: 0.58
DE  Interaction: Q02821; IntAct: EBI-15598611; Score: 0.76
DE  Interaction: P32462; IntAct: EBI-789522; Score: 0.35
DE  Interaction: P47088; IntAct: EBI-856789; Score: 0.00
DE  Interaction: P11484; IntAct: EBI-3689025; Score: 0.35
DE  Interaction: P32589; IntAct: EBI-3805388; Score: 0.35
DE  Interaction: P02829; IntAct: EBI-3811847; Score: 0.35
DE  Interaction: P52917; IntAct: EBI-10053328; Score: 0.40
GO  GO:0016021;
GO  GO:0005635;
GO  GO:0005637;
GO  GO:0034399;
GO  GO:0003682;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MDHRNLDPKTLKVSQLRRVLVENDVAFPANARKPVLVKLFEEKVRQRLQSSPEASKVRTSIQKVVKSGAKNADRKKTLKS
SQ  KKLESSSSESKTVKDENVETNKRKREQISTDNEAKMQIQEEKSPKKKRKKRSSKANKPPESPPQSKSDGKATSADLTSEL
SQ  ETVEELHKKDSSDDKPRVKELPKPELPNLKVSNEFLAQLNKELASAATENYDHSIKSTDLSSIRIETEEPVGPSTGAETR
SQ  NESEVMENINLEVQPEVKEAKEELTKISETFDNQDEEDTSRLSSKKNIRSPKGRTRHFIANKTKRGIDIMKPFIAHLFIW
SQ  LWNGAIFLSIICPILFGLWYREQRIQVGYCGHEKPLKSLAISAFPQTERVDSVLQAYRPNCLECPEHGICSSFMNVECEP
SQ  GYEPKSSILETYGIIPFPKYCAKDESKEKEVDELVWKVNEYLKKKNAQHECGEGENLFESGETETKLYDIFSHSRPSWES
SQ  QREFNDHWKNVLEILKKKDDIIWLPLDFETNGKREKSKSNNTNYIYRSTSKKWVTLQCHLEGDIQEYITKYGGSLFITLG
SQ  VLFLIKKIQSTLDNYVQGEQIIEKLVKEAIDKLKDVKKNKGEEPFLTTVQLRATLLSDIPNIKEQNNLWAQTKEKIMKEQ
SQ  SENIELYLLEENGEIMTCWEWKE
//