ID  Q09825;
PN  Spindle pole body-associated protein sad1;
GN  sad1;
OS  284812;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Cytoplasm, cytoskeleton, microtubule organizing center, spindle pole body. Nucleus membrane; Single-pass membrane protein.
DR  UNIPROT: Q09825;
DR  UNIPROT: Q9UU40;
DR  PDB: 6A6W;
DR  Pfam: PF07738;
DR  PROSITE: PS51469;
DE  Function: Associates with the spindle pole body and maintains a functional interface between the nuclear membrane and the microtubule motor proteins. Involved in chromosome segregation during meiosis where it associates with the telomeres. {ECO:0000269|PubMed:16615890}.
DE  Reference Proteome: Yes;
DE  Interaction: O13712; IntAct: EBI-1557581; Score: 0.55
DE  Interaction: O74446; IntAct: EBI-1557543; Score: 0.37
DE  Interaction: Q92358; IntAct: EBI-929742; Score: 0.46
DE  Interaction: Q9US52; IntAct: EBI-929836; Score: 0.32
DE  Interaction: Q9UU83; IntAct: EBI-1542573; Score: 0.37
DE  Interaction: P87245; IntAct: EBI-1557414; Score: 0.55
DE  Interaction: O13802; IntAct: EBI-1557451; Score: 0.37
DE  Interaction: Q9USK8; IntAct: EBI-1557455; Score: 0.37
DE  Interaction: O13779; IntAct: EBI-1557461; Score: 0.37
DE  Interaction: O74388; IntAct: EBI-1557470; Score: 0.37
DE  Interaction: O60187; IntAct: EBI-1557475; Score: 0.37
DE  Interaction: O42914; IntAct: EBI-1557484; Score: 0.37
DE  Interaction: O94531; IntAct: EBI-1557488; Score: 0.37
DE  Interaction: O43087; IntAct: EBI-1557492; Score: 0.37
DE  Interaction: O59678; IntAct: EBI-1557498; Score: 0.37
DE  Interaction: Q9HFE5; IntAct: EBI-1557503; Score: 0.37
DE  Interaction: Q9USM3; IntAct: EBI-1557507; Score: 0.37
DE  Interaction: Q09874; IntAct: EBI-1557511; Score: 0.37
DE  Interaction: Q09877; IntAct: EBI-1557515; Score: 0.37
DE  Interaction: O94486; IntAct: EBI-1557520; Score: 0.37
DE  Interaction: P87128; IntAct: EBI-1557524; Score: 0.37
DE  Interaction: O74843; IntAct: EBI-1557528; Score: 0.37
DE  Interaction: P87074; IntAct: EBI-1557547; Score: 0.37
DE  Interaction: P78820; IntAct: EBI-1557554; Score: 0.37
DE  Interaction: Q9P6M1; IntAct: EBI-1557559; Score: 0.37
DE  Interaction: Q9UTE0; IntAct: EBI-1557577; Score: 0.37
DE  Interaction: O74338; IntAct: EBI-1557585; Score: 0.37
DE  Interaction: Q09825; IntAct: EBI-1542715; Score: 0.55
DE  Interaction: O42667; IntAct: EBI-1556648; Score: 0.27
DE  Interaction: Q10336; IntAct: EBI-1562137; Score: 0.27
DE  Interaction: P50528; IntAct: EBI-8529503; Score: 0.27
DE  Interaction: O13787; IntAct: EBI-21242797; Score: 0.37
DE  Interaction: Q10322; IntAct: EBI-21242908; Score: 0.37
DE  Interaction: P10815; IntAct: EBI-21245606; Score: 0.37
GO  GO:0005737;
GO  GO:0061497;
GO  GO:0005639;
GO  GO:0031021;
GO  GO:0034993;
GO  GO:0090619;
GO  GO:0035974;
GO  GO:0005874;
GO  GO:0044732;
GO  GO:0071958;
GO  GO:0005635;
GO  GO:0071957;
GO  GO:1990612;
GO  GO:0035861;
GO  GO:0043495;
GO  GO:0106166;
GO  GO:0051301;
GO  GO:0072766;
GO  GO:0032121;
GO  GO:0140480;
GO  GO:0006998;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MFTNTPVGGKRERQNGAHPAWSTLGANSAQIHQNTADLASKMHKLRYTKIRSPPTRVSIESITPKQRFPAPNFEQAYHSN
SQ  IRYEQEESDNEEFENVVKNGHEASTNVFYESDGDDEEFVNEEYENSIDEESDDEGYSLNEDTTATNASFRYPMNQRSTRK
SQ  SQFYSSKFKPLLWFGITLFSTLLIITLLHKGQEFYSRSFSSDNSQPSNSPVPNIPPASNDTKTSLKPDIIKDFTDSPSKV
SQ  GGNEEFDYSTGDLITKKEFDKILQQKVEQLKQSLKEEMSNYKSSVPFEVELNDDWKFFIESTVRKYLTDPVSMPNFALLS
SQ  TGAEVLPALTSKRYVRRPSAFIPRFTSYFFDSLVVRGHEPSIALTPNNAVAMCWSFQGSEGQLGISLSRPVYVTNVTIEH
SQ  VQHKIAHDLSSAPKDFELWVQGMSSKMFVLLGKARYSLTEDSIQTFSFESSNYIVAEPIQNVILKIKSNWGNPNYTCLYQ
SQ  VRVHGTVPNADEQPIPSLGEKAESTAENTGQDSS
//