ID  Q10099;
PN  Nucleoporin seh1;
GN  seh1;
OS  284812;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0185;
SL  Comments: Cytoplasm. Nucleus, nuclear pore complex.
DR  UNIPROT: Q10099;
DR  Pfam: PF00400;
DR  PROSITE: PS50082;
DR  PROSITE: PS50294;
DE  Function: Functions as a component of the nuclear pore complex (NPC). NPC components, collectively referred to as nucleoporins (NUPs), can play the role of both NPC structural components and of docking or interaction partners for transiently associated nuclear transport factors. Active directional transport is assured by both, a Phe-Gly (FG) repeat affinity gradient for these transport factors across the NPC and a transport cofactor concentration gradient across the nuclear envelope. {ECO:0000269|PubMed:15116432}.
DE  Reference Proteome: Yes;
DE  Interaction: O43044; IntAct: EBI-1563770; Score: 0.40
DE  Interaction: Q9UUE5; IntAct: EBI-1563788; Score: 0.35
DE  Interaction: Q9UTK4; IntAct: EBI-1563788; Score: 0.35
GO  GO:0005829;
GO  GO:0061700;
GO  GO:0034399;
GO  GO:0005643;
GO  GO:0031080;
GO  GO:0005634;
GO  GO:0035859;
GO  GO:0005774;
GO  GO:0005198;
GO  GO:0034198;
GO  GO:0051028;
GO  GO:1904263;
GO  GO:0015031;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MDDISATTIQTNHQDLVNDVTYDFYGRRMVSCSADQRVKVYDFNDDTETWAITSEWRAGDASLMRVAWAHPSFGQVLAVC
SQ  SLDRGVRIYEEQKKNFESKTWVEVAKLMDARSAVLDISFCPFQHGCKLAAVSADATLRIYEAMEPGNLTYWTLMNEIALM
SQ  PSPPSRNEQPAFCVNWCPSRWREQYIAVGCMNDAYIYKQNSHGKWKKVAELPGHTDLIRDICWAPSMGSSYYLIATACKD
SQ  GNVRIFKVETLCEEVFQEEEDAGNSMTEDSNFNLNSLKVELIGEYDNHKCQVWRCRFNVTGTILSSSGDDGCVRLWKASY
SQ  ANLFKCISVVSLEKKPEKL
//