ID  Q14728;
PN  Major facilitator superfamily domain-containing protein 10;
GN  MFSD10;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000250|UniProtKB:Q9D2V8}; Multi-pass membrane protein {ECO:0000255}.
DR  UNIPROT: Q14728;
DR  UNIPROT: Q07706;
DR  PDB: 6S4M;
DR  Pfam: PF07690;
DR  PROSITE: PS50850;
DR  OMIM: 610977;
DE  Function: Confers cellular resistance to apoptosis induced by the non- steroidal anti-inflammatory drugs indomethacin and diclofenac. May act as an efflux pump. {ECO:0000269|PubMed:17362938}.
DE  Reference Proteome: Yes;
DE  Interaction: P0C739; IntAct: EBI-11725101; Score: 0.35
DE  Interaction: Q6NUS6; IntAct: EBI-11368748; Score: 0.27
DE  Interaction: Q96GX1; IntAct: EBI-11375285; Score: 0.27
DE  Interaction: H9XIJ5; IntAct: EBI-11514331; Score: 0.37
DE  Interaction: O94886; IntAct: EBI-21566099; Score: 0.35
DE  Interaction: P55085; IntAct: EBI-20806731; Score: 0.37
DE  Interaction: Q6W5P4; IntAct: EBI-20810842; Score: 0.37
DE  Interaction: P19739; IntAct: EBI-25685423; Score: 0.35
DE  Interaction: P0DTD8; IntAct: EBI-25687199; Score: 0.35
DE  Interaction: Q7TFA1; IntAct: EBI-25688644; Score: 0.35
DE  Interaction: P16284; IntAct: EBI-25881341; Score: 0.56
DE  Interaction: Q92876; IntAct: EBI-25887528; Score: 0.56
DE  Interaction: P37173; IntAct: EBI-25892796; Score: 0.56
DE  Interaction: P45973; IntAct: EBI-25917360; Score: 0.56
GO  GO:0031526;
GO  GO:0030659;
GO  GO:0016021;
GO  GO:0005637;
GO  GO:0008514;
GO  GO:0008493;
GO  GO:0006915;
GO  GO:0043252;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPLYGSWQGGVDWFATAIGMPVE
SQ  KRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLS
SQ  TAIVADLGSPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
SQ  DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMA
SQ  TIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTL
SQ  RSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
//