ID  Q15283;
PN  Ras GTPase-activating protein 2;
GN  RASA2;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm. Cytoplasm, perinuclear region.
DR  UNIPROT: Q15283;
DR  UNIPROT: A8K7K1;
DR  UNIPROT: G3V0F9;
DR  UNIPROT: O00695;
DR  UNIPROT: Q15284;
DR  UNIPROT: Q92594;
DR  UNIPROT: Q99577;
DR  UNIPROT: Q9UEQ2;
DR  Pfam: PF00779;
DR  Pfam: PF00168;
DR  Pfam: PF00169;
DR  Pfam: PF00616;
DR  PROSITE: PS50004;
DR  PROSITE: PS50003;
DR  PROSITE: PS00509;
DR  PROSITE: PS50018;
DR  PROSITE: PS51113;
DR  OMIM: 601589;
DR  DisGeNET: 5922;
DE  Function: Inhibitory regulator of the Ras-cyclic AMP pathway. Binds inositol tetrakisphosphate (IP4).
DE  Reference Proteome: Yes;
GO  GO:0005829;
GO  GO:0048471;
GO  GO:0005096;
GO  GO:0046872;
GO  GO:0005543;
GO  GO:0035556;
GO  GO:0046580;
GO  GO:0043087;
GO  GO:0007165;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAAAAPAAAAASSEAPAASATAEPEAGDQDSREVRVLQSLRGKICEAKNLLPYLGPHKMRDCFCTINLDQEEVYRTQVVE
SQ  KSLSPFFSEEFYFEIPRTFQYLSFYVYDKNVLQRDLRIGKVAIKKEDLCNHSGKETWFSLQPVDSNSEVQGKVHLELKLN
SQ  ELITENGTVCQQLVVHIKACHGLPLINGQSCDPYATVSLVGPSRNDQKKTKVKKKTSNPQFNEIFYFEVTRSSSYTRKSQ
SQ  FQVEEEDIEKLEIRIDLWNNGNLVQDVFLGEIKVPVNVLRTDSSHQAWYLLQPRDNGNKSSKTDDLGSLRLNICYTEDYV
SQ  LPSEYYGPLKTLLLKSPDVQPISASAAYILSEICRDKNDAVLPLVRLLLHHDKLVPFATAVAELDLKDTQDANTIFRGNS
SQ  LATRCLDEMMKIVGGHYLKVTLKPILDEICDSSKSCEIDPIKLKEGDNVENNKENLRYYVDKLFNTIVKSSMSCPTVMCD
SQ  IFYSLRQMATQRFPNDPHVQYSAVSSFVFLRFFAVAVVSPHTFHLRPHHPDAQTIRTLTLISKTIQTLGSWGSLSKSKSS
SQ  FKETFMCEFFKMFQEEGYIIAVKKFLDEISSTETKESSGTSEPVHLKEGEMYKRAQGRTRIGKKNFKKRWFCLTSRELTY
SQ  HKQPGSKDAIYTIPVKNILAVEKLEESSFNKKNMFQVIHTEKPLYVQANNCVEANEWIDVLCRVSRCNQNRLSFYHPSVY
SQ  LNGNWLCCQETGENTLGCKPCTAGVPADIQIDIDEDRETERIYSLFTLSLLKLQKMEEACGTIAVYQGPQKEPDDYSNFV
SQ  IEDSVTTFKTIQQIKSIIEKLDEPHEKYRKKRSSSAKYGSKENPIVGKAS
//