ID  Q18250;
PN  Early growth response factor homolog 1;
GN  egrh;
OS  6239;
SL  Nucleus Position: SL-0198;
SL  Comments: Nucleus {ECO:0000269|PubMed:20736289}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:20736289}. Note=Perinuclear localization only observed in sperm. {ECO:0000269|PubMed:20736289}.
DR  UNIPROT: Q18250;
DR  Pfam: PF00096;
DR  PROSITE: PS00028;
DR  PROSITE: PS50157;
DE  Function: Sequence-specific DNA-binding transcription factor (By similarity). Plays a role in oocyte development, acting cell- autonomously in the somatic gonad (PubMed:20736289). Involved in negative regulation of oocyte MAPK activation and inhibits oocyte maturation and ovulation (PubMed:20736289). {ECO:0000250|UniProtKB:P11161, ECO:0000269|PubMed:20736289}.
DE  Reference Proteome: Yes;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0000981;
GO  GO:0046872;
GO  GO:0000978;
GO  GO:0043407;
GO  GO:1900194;
GO  GO:0060280;
GO  GO:0006357;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MALHEPPSKLNRHSHSNLLKPPSLNKPILTFADNDCLKTPTMNDMLKTPTVNSPRHTPMNIDGTPKVNGFSGFTPQTDQK
SQ  FFGEHEPLFNQMHTTTLMPAPSSSYKEPAYSSEQPSSSSDEAKPKELLGSNSFGVPRMTNGNSKQKPEELTLKDIEISST
SQ  GPGGVDSPGLSAAMFQFSPMVEHFLQNLTNKAGLPELVVDSKTAGLNHQEPSDLIKSVQVRRSSIEDQKFSDVLHVPTLP
SQ  RKTSEPSHLGSSLQNEHPQSNSRPSTVIPRVQRTNTSASLTRSMDHSSMSPISAHDDPYSNSASYSSLSTHTSFSDSASL
SQ  AHFEPKTEPMDDYSYNFSDNDFNSFEFSSTSEELKNIGCQKMKSSKMPLQDRPYKCPRDGCDRRFSRSDELTRHIRIHTG
SQ  QKPFQCRICMRAFSRSDHLTTHVRTHTGEKPFSCDICGRKFARSDERKRHTKVHKTSRSGS
//