ID  Q19293;
PN  Nuclear envelope integral membrane protein;
GN  nemp;
OS  6239;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000250|UniProtKB:Q6ZQE4}; Multi-pass membrane protein {ECO:0000255}; Nucleoplasmic side {ECO:0000250|UniProtKB:B9X187}.
DR  UNIPROT: Q19293;
DR  Pfam: PF10225;
DE  Function: Contributes to nuclear envelope stiffness in germ cells (By similarity). Required for fertility (PubMed:32923640). {ECO:0000250|UniProtKB:O14524, ECO:0000269|PubMed:32923640}.
DE  Reference Proteome: Yes;
DE  Interaction: O17915; IntAct: EBI-338738; Score: 0.00
GO  GO:0016021;
GO  GO:0005635;
GO  GO:0005637;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MRLLTLALLVAGSLAYKFEDCEQKPAALNQVLRVGAKLYSYNLDFFYQKALPYNAIYAFTDVFLQTNLTNADQYQFYQGT
SQ  NCTTVQQLYDNDNRYFGILRKAALLRSHQLNPFNDTIVGVSTTEPYEISVLIWKVNYFRVGVYVGAIVLFLLASKLVRNV
SQ  VFYYTSGCSFGLLASLLLVAFIVWRVAPKKTIGVPILIGGWSVSLYMLHFAWSNLQSIMIEYQKYVIGYFATVLLISMAV
SQ  CYKRGPPTDARSHDIAQWTLQLVALALIYFSVQMVEVSTGTIGALIIQQICRGFLFAGIRWYFVGLKAVWRKFFPARRRL
SQ  LNEEEYEEQAEKTTKEQLAQLREYCKKEGNRPWKIAGNVRSARRLARFIEGEDDHITEDEIYAHELTGDVLDDEDYDFNE
SQ  DYGLRTPNESHFDLEDDEDGAEEWDEVVVRRRASEYGRDSVQSVRVPRSVSSRLLSPYQGQNHMNRSLGPGIGFRRDSTP
SQ  RHGNFQSEHRPRMPRTEQIYRSRRVEYDVKNGRVEGPSSSTASGMTPSEYMRKARRIDATSKTPTRKSRHPTESEDADE
//