ID  Q19972;
PN  Chromo domain-containing protein cec-4;
GN  cec;
OS  6239;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000269|PubMed:26607792}. Membrane {ECO:0000305|PubMed:26607792}; Peripheral membrane protein {ECO:0000305|PubMed:26607792}.
DR  UNIPROT: Q19972;
DR  Pfam: PF00385;
DR  PROSITE: PS50013;
DE  Function: Chromatin anchor protein which binds to methylated lysine residues on histone H3, thereby recruiting heterochromatin to the nuclear periphery, especially in embryonic cells, with a lesser role in differentiated cells (PubMed:26607792, PubMed:31118512). May be required for the correct positioning of chromatin and nucleoli in embryos (PubMed:26607792). {ECO:0000269|PubMed:26607792, ECO:0000269|PubMed:31118512}.
DE  Reference Proteome: Yes;
GO  GO:0000793;
GO  GO:0005637;
GO  GO:0003682;
GO  GO:0035064;
GO  GO:0097240;
GO  GO:0045595;
GO  GO:0010468;
TP  Membrane Topology: Peripheral; Source: UniProt - Curator Inference {ECO:0000305|PubMed:26607792};
SQ  MAKKTVEGEHGTPKTNFTKKETSKNHDDFKKIIGHKVVEEHYVEYEVELTSGKTITATEFDFKGDDSLLSTYKKKVTKQS
SQ  DDSSGEYAVERVLAHRKVKGSPLYLVQWKGYPHPVWNSEMWEEDLDNCKDLLAAYKKHQEDLKIAQTPKKTPSKTPKKTP
SQ  KSLKRRALTPSDDEEEAGPIAPEPKKTPKQSTKKLKRTTSPETNLVEKSKKKAIPDLENHTLDQEKNDVIERVEEIQEDE
SQ  DDDDEQREEVVTTAPVETKSRWGFGSWKWF
//