ID  Q1LZF8;
PN  Chloride channel CLIC-like protein 1;
GN  CLCC1;
OS  9913;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9WU61}; Multi-pass membrane protein {ECO:0000255}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9WU61}; Multi-pass membrane protein {ECO:0000255}. Nucleus membrane {ECO:0000250|UniProtKB:Q9WU61}; Multi-pass membrane protein {ECO:0000255}. Note=Within the endoplasmic reticulum (ER), localizes to the mitochondria-associated ER membrane, a zone of contact between the ER and mitochondrial membranes. {ECO:0000250|UniProtKB:Q96S66}.
DR  UNIPROT: Q1LZF8;
DR  Pfam: PF05934;
DE  Function: Seems to act as a chloride ion channel (By similarity). Plays a role in retina development (By similarity). {ECO:0000250|UniProtKB:Q99LI2, ECO:0000250|UniProtKB:Q9WU61}.
DE  Reference Proteome: Yes;
GO  GO:0034707;
GO  GO:0005783;
GO  GO:0005789;
GO  GO:0000139;
GO  GO:0044233;
GO  GO:0031965;
GO  GO:0005254;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MLYSLLLCECLWLITAYAHDDEWIDPTDMLNYDAASGRMRKSQVKYGISEKEEVNPDLSCANELSECYNRLDSLTYKIDE
SQ  CEKQKRKDYESQSNPVFRRYLNKILIETKKLGLPDENKHDMHYDAEIILKRQTLLEIQKFLSGEDWKPGALDDALSDILI
SQ  NFKFHDFETWKWRFEEFFGVDPYNVFMVLLCLLCIVALVATELWTYVRWYTQLKRVFFISFLISLGWNWMYLYKLAFAQH
SQ  QAEVAKMEPLNNVCAEKMNWSGSLWEWLRSSWTYKDDPCQKYYELLLVNPIWLVPPTKALAVTFTNFVTEPLKHVGKGAG
SQ  EFIKALMKEIPVLLHIPVLIIMALAVLSFCYGAGKSVNMLRHVGGPEREAPQALQAGERRRQQKIDYRPHGGAGDADFYY
SQ  RGQISPIEQGPNDNTYEGRRDVLRERDVGLRFQTGNKSPEVLRPFDLQEAEAREHPKVVPGLKSPNLESKPREMGEIPGE
SQ  STPTESSTESSQPAKPVSGQKVSEGVEGCPAVEKAQLRTDAAGGPEEGSTCSPASTAVEVCG
//