ID  Q3UBX0;
PN  Transmembrane protein 109;
GN  Tmem109;
OS  10090;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Nucleus Position: SL-0183;
SL  Comments: Nucleus outer membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}. Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}. Sarcoplasmic reticulum membrane {ECO:0000250|UniProtKB:O77751}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O77751}.
DR  UNIPROT: Q3UBX0;
DR  UNIPROT: Q8R006;
DE  Function: May mediate cellular response to DNA damage by protecting against ultraviolet C-induced cell death (PubMed:20060811). Can form voltage-gated calcium and potassium channels in vitro (By similarity). {ECO:0000250|UniProtKB:O77751, ECO:0000250|UniProtKB:Q9BVC6, ECO:0000269|PubMed:20060811}.
DE  Reference Proteome: Yes;
DE  Interaction: O00141; IntAct: EBI-2363087; Score: 0.37
DE  Interaction: P02511; IntAct: EBI-8508071; Score: 0.51
DE  Interaction: P52927; IntAct: EBI-9986179; Score: 0.35
DE  Interaction: P04844; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q9Y3E0; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: G5E9A6; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: P45880; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q99623; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: P51572; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: P35232; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q9BTV4; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: E7EWD6; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q9HCK4; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q9NWS8; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: Q9UQ84; IntAct: EBI-11055815; Score: 0.35
DE  Interaction: P21796; IntAct: EBI-11055815; Score: 0.35
GO  GO:0005783;
GO  GO:0016021;
GO  GO:0031965;
GO  GO:0005640;
GO  GO:0033017;
GO  GO:0005244;
GO  GO:0071480;
GO  GO:0042771;
GO  GO:0060548;
GO  GO:0034765;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MAGAHSTPLWSRHLLKAVLMVLVALFLVHSASAQSHREFASPGQQKKETSADILTQIGRSLKEMLDTWLGPETMHVISET
SQ  LLQVMWAISSAISVACFALSGIAAQLLSALGLDGEQLTQGLKLSPSQVQTLLLWGAAALVIYWLLSLLLGLVLALLGRIL
SQ  GGLKLVLFVAGFVALVRSVPDPSTRALMLLALLTLFALLSRLTGSRSSGSHLEAKVRGLERQIEELRGRQRRAAKMPRSM
SQ  EEE
//