ID  Q4ADG7;
PN  Interferon-induced GTP-binding protein Mx1;
GN  MX1;
OS  161932;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Binds preferentially to negatively charged phospholipids. {ECO:0000250}.
DR  UNIPROT: Q4ADG7;
DR  Pfam: PF01031;
DR  Pfam: PF00350;
DR  Pfam: PF02212;
DR  PROSITE: PS00410;
DR  PROSITE: PS51718;
DR  PROSITE: PS51388;
DE  Function: Interferon-induced dynamin-like GTPase with antiviral activity. {ECO:0000250}.
DE  Reference Proteome: No;
GO  GO:0005737;
GO  GO:0005789;
GO  GO:0048471;
GO  GO:0005525;
GO  GO:0003924;
GO  GO:0051607;
GO  GO:0045087;
TP  Membrane Topology: Peripheral; Source: UniProt - By Similarity {ECO:0000250};
SQ  MVNSKGKITDSDPGSSHLLLNGLADKAGKNQDTEPENSLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSG
SQ  KSSVLEALSGVALPRGSGIVTRCPLVLKLKKLLNKDEWRGKVSYQDFEMEISDPSEVEVEINKAQNAIAGEGQGISHELI
SQ  SLEVSSPHVPDLTLIDLPGITRVAVGNQPADIGHQTKKLIKKYILKQETINLVVVPCNVDIATTEALSMAQEVDPDGDRT
SQ  IGILTKPDLVDRGTESKVVDVAQNLVCHLKKGYMIVKCRGQQDIQDQVTLTEALQKERDFFEDHPHFRVLLEEGRATVPC
SQ  LADRLTSELITHICKTLPLLEKQIKENYEKITEELQKYGSDVPEEEHEKMFFLIEKINAFNHDITSLTEGEEFVGEDECR
SQ  LFTKIRNEFHKWSLVIEKRFQQGYKAICKQIERFENRYRGRELPGFVNYKTFEIIIKQQIKELEEPAVYMLHTITDMVQA
SQ  AFTDISEANFAEFFNLYRTTKSKIEDIKFELEKEAEKSIRLHFQMEQIVYCQDQVYQCALQRVREESDKEKDKKINSMCS
SQ  KEVSSVNISLSDIFEHLLAYRQEATNRISSHIPLIIQYFILQVYGQKLQKDMLLLLHDKDTHNWLLKERSDTRDKRKLLK
SQ  ERLARLAQARRRLAKFPG
//