ID  Q4KM77;
PN  Etoposide-induced protein 2.4 homolog;
GN  Ei24;
OS  10116;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Cytoplasm {ECO:0000250}. Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
DR  UNIPROT: Q4KM77;
DE  Function: Acts as a negative growth regulator via p53-mediated apoptosis pathway. Regulates formation of degradative autolysosomes during autophagy. {ECO:0000269|PubMed:20550938}.
DE  Reference Proteome: Yes;
GO  GO:0005829;
GO  GO:0005783;
GO  GO:0005789;
GO  GO:0005794;
GO  GO:0016021;
GO  GO:0031965;
GO  GO:0061676;
GO  GO:0006914;
GO  GO:0071494;
GO  GO:0008630;
GO  GO:0016236;
GO  GO:0030308;
GO  GO:0042308;
GO  GO:0050885;
GO  GO:2001244;
GO  GO:0009410;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MADSVKTFLQDLGRGIKDSIWGICTISKLDARIQQKREEQRRRRASSLLAQRRAQSVERKQESEPRIVSRIFQCCAWNGG
SQ  VFWFSLLLFYRVFIPVLQSVTARVIGDPSLHGDVWSWLEFFLTSIFSALWVLPLFVLSKVVNAIWFQDIADLAFEVSGRK
SQ  PHPFPSVSKIIADMLFNLLLQALFLIQGMFVSLFPIHLVGQLVSLLHMSLLYSLYCFEYRWFNKGIEMHQRLSNIERNWP
SQ  YYFGFGLPLAFLTAMQSSYIISGCLFSILFPLFIISANEAKTPGKAYLFQLRLFSLVVFLSNRLFHKTVYLQSALSSSSS
SQ  AEKFPSPHPSPAKLKAAAGH
//