ID  Q53HI1;
PN  Protein unc-50 homolog;
GN  UNC50;
OS  9606;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane {ECO:0000250|UniProtKB:O55227}; Multi-pass membrane protein {ECO:0000250|UniProtKB:O55227}. Golgi apparatus membrane {ECO:0000269|PubMed:12808035}; Multi-pass membrane protein {ECO:0000269|PubMed:12808035}.
DR  UNIPROT: Q53HI1;
DR  UNIPROT: D3DVH4;
DR  UNIPROT: Q53S98;
DR  UNIPROT: Q53TD6;
DR  UNIPROT: Q5U5U2;
DR  UNIPROT: Q6X7B9;
DR  UNIPROT: Q9UQF4;
DR  UNIPROT: Q9Y4S6;
DR  Pfam: PF05216;
DR  OMIM: 617826;
DR  DisGeNET: 25972;
DE  Function: Involved in the cell surface expression of neuronal nicotinic receptors (By similarity). Binds RNA (By similarity). {ECO:0000250|UniProtKB:O55227}.
DE  Reference Proteome: Yes;
DE  Interaction: Q15125; IntAct: EBI-23922913; Score: 0.56
DE  Interaction: P47102; IntAct: EBI-7601754; Score: 0.37
DE  Interaction: O43889; IntAct: EBI-8647641; Score: 0.55
DE  Interaction: P05214; IntAct: EBI-10992821; Score: 0.35
DE  Interaction: Q96N21; IntAct: EBI-11139757; Score: 0.35
DE  Interaction: Q9GZY8; IntAct: EBI-24312848; Score: 0.56
DE  Interaction: Q8IUN9; IntAct: EBI-24623370; Score: 0.56
DE  Interaction: Q9NR31; IntAct: EBI-24661428; Score: 0.56
DE  Interaction: Q7Z5P4; IntAct: EBI-23694082; Score: 0.56
DE  Interaction: Q9Y282; IntAct: EBI-24676607; Score: 0.56
DE  Interaction: Q9H2K0; IntAct: EBI-23703501; Score: 0.56
DE  Interaction: O14880; IntAct: EBI-24689376; Score: 0.56
DE  Interaction: Q5SR56; IntAct: EBI-24705233; Score: 0.56
DE  Interaction: Q8N6M3; IntAct: EBI-24710182; Score: 0.56
DE  Interaction: Q8TED1; IntAct: EBI-23762119; Score: 0.56
DE  Interaction: Q8TDT2; IntAct: EBI-24713756; Score: 0.56
DE  Interaction: P48051; IntAct: EBI-24716932; Score: 0.56
DE  Interaction: Q14973; IntAct: EBI-24719889; Score: 0.56
DE  Interaction: Q9NUH8; IntAct: EBI-24731178; Score: 0.56
DE  Interaction: Q9NRX6; IntAct: EBI-24742634; Score: 0.56
DE  Interaction: Q3KNW5; IntAct: EBI-24747464; Score: 0.56
DE  Interaction: Q8NBQ5; IntAct: EBI-24750500; Score: 0.56
DE  Interaction: Q9H6H4; IntAct: EBI-24770276; Score: 0.56
DE  Interaction: P38484; IntAct: EBI-24782805; Score: 0.56
DE  Interaction: Q8WY98; IntAct: EBI-24793740; Score: 0.56
DE  Interaction: Q9GZR5; IntAct: EBI-24797356; Score: 0.56
DE  Interaction: O95470; IntAct: EBI-23908976; Score: 0.56
DE  Interaction: Q6PL24; IntAct: EBI-24545316; Score: 0.56
DE  Interaction: Q5JX71; IntAct: EBI-24651712; Score: 0.56
DE  Interaction: O15552; IntAct: EBI-25189572; Score: 0.56
DE  Interaction: P15941; IntAct: EBI-24803639; Score: 0.56
DE  Interaction: Q6PI48; IntAct: EBI-25221026; Score: 0.56
DE  Interaction: Q13520; IntAct: EBI-25227998; Score: 0.56
DE  Interaction: P58418; IntAct: EBI-25272729; Score: 0.56
DE  Interaction: P0DTC5; IntAct: EBI-25685699; Score: 0.35
GO  GO:0030173;
GO  GO:0005637;
GO  GO:0003723;
GO  GO:0034394;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MLPSTSVNSLVQGNGVLNSRDAARHTAGAKRYKYLRRLFRFRQMDFEFAAWQMLYLFTSPQRVYRNFHYRKQTKDQWARD
SQ  DPAFLVLLSIWLCVSTIGFGFVLDMGFFETIKLLLWVVLIDCVGVGLLIATLMWFISNKYLVKRQSRDYDVEWGYAFDVH
SQ  LNAFYPLLVILHFIQLFFINHVILTDTFIGYLVGNTLWLVAVGYYIYVTFLGYSALPFLKNTVILLYPFAPLILLYGLSL
SQ  ALGWNFTHTLCSFYKYRVK
//