ID  Q54ED3;
PN  DnaJ homolog subfamily A member 1 homolog;
GN  dnaja1;
OS  44689;
SL  Nucleus Position: SL-0198;
SL  Comments: Membrane {ECO:0000305}; Lipid-anchor {ECO:0000305}. Cytoplasm {ECO:0000250}. Microsome {ECO:0000250}. Mitochondrion {ECO:0000250}. Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Primarily cytoplasmic and associated with microsomes. A minor proportion is associated with nuclei and mitochondria (By similarity). {ECO:0000250}.
DR  UNIPROT: Q54ED3;
DR  Pfam: PF00226;
DR  Pfam: PF01556;
DR  Pfam: PF00684;
DR  PROSITE: PS00636;
DR  PROSITE: PS50076;
DR  PROSITE: PS51188;
DE  Function: Co-chaperone for Hsp70 family members. Plays a role in protein transport into mitochondria and in the regulation of apoptosis via its role as co-chaperone (By similarity). {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0005783;
GO  GO:0016020;
GO  GO:0005739;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0005524;
GO  GO:0051087;
GO  GO:0030544;
GO  GO:0046872;
GO  GO:0051082;
GO  GO:0042026;
GO  GO:0009408;
TP  Membrane Topology: Lipid-Anchored; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MVKEKEYYERLGVKPDCTEDELKKAYRKMAVKYHPDKNQGPGKDAAEAKFKDISEAYEVLSDPEKRKMYDSYGSEGMKES
SQ  GFHASSAEDLFSHFFGAGGGGGGFSFGGGGGDDFGGFSFGNMGGMGGMGGMGGGHKKRRKGEDIEHEMNRSLEELYNGKL
SQ  VKISISRDEVCKTCKGSGSNKPGVTTTCPTCNGSRYVFQKKQVGPGMIQQVQTACHTCHGTGEKIKEEDKCKECKGKRVI
SQ  QGKKIVQFQVEKGTRDGERIMLQGQGSEYPGVPPGDVIITIREKPNVNFKRNGDNLIYTKRLKLLDSIAGSQFIINTLDQ
SQ  RKLWVNHEKGDIIKQGDMRYIENEGMPIKGTSRKGKLIIAFDIEYPSNLTNDDIEKLSKILPKAATPSVSKSDCKSVGLS
SQ  KVNFNTNEQSSHGGAGGAYQQHGGAYGHQKQQQQGFNPADFGAQFGGGGPQQAQQCQQQ
//