ID  Q54EV7;
PN  Exportin-1;
GN  xpo1;
OS  44689;
SL  Nucleus Position: SL-0198;
SL  Comments: Nucleus {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Shuttles between the nucleus and the cytoplasm. {ECO:0000250}.
DR  UNIPROT: Q54EV7;
DR  Pfam: PF08767;
DR  Pfam: PF18777;
DR  Pfam: PF18784;
DR  Pfam: PF18787;
DR  Pfam: PF03810;
DR  Pfam: PF08389;
DR  PROSITE: PS50166;
DE  Function: Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES).
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0005049;
GO  GO:0031267;
GO  GO:0006611;
GO  GO:0000055;
GO  GO:0000056;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MENILNFNEPLDINLLDQIVSVLYNPLSNKNDIKAAQMVLGKFQEHPDAWSKVDTILETSKIVQTKFIALVIMDSLIKYR
SQ  WKSLPREQCEGIKNYIVSLIIRLSSDPQTSSREKLLVNKLNLVFVQILKQEWTTNWSTFIPEIISSSKTNESLCENNMVI
SQ  LRLLSEEIFNFSEEQMTQTKIQTLKITFEKEFSLINDLCFYILENATRASLIKATLETLQRFLNWVPLHYIIEVNGGIAE
SQ  PSKLVKLLLHKYFPEPLFRNSTLKCLTEIGNLNLGNQQYDAVFIAIIDKFMNQIKFIKPDPSKIPQDYEDGDQGERSFIH
SQ  TVSLFLTGFFKSHLKIMENSLNIPYLTLAHEILVNISNIDELELFKICLEYWNFLSSNLYSDIATFTTTLLSTPPRLQLY
SQ  KSVLSKVRVVLIDHMAKPEEVIVVEDENGNIVRETTKDTDSLTLYESMRETLIFLTHLDSENTQHIMLEKLQTLISGREF
SQ  TFQRLNTLCWAIGSISGAQNKEQEKRFLVTVIKDLLELCQNKKGKDNKAVIASDIMYIVGQYPRFLKDHWKFLKTVVNKL
SQ  FEFMHESHPGVQDMACDTFLKISKQCKRKFVVLQVEESQPFINELLNQLSTTIAHLEQSQIHTFYEAVGYMIASSSDAAF
SQ  REKLVNKFMELPNHSWLQIMGAASVKVESLLTVEVARDILNLIKTNNRAAMSLENCYITQISKIYLDLLNVYRTYSDHIS
SQ  RNPNIYRETLGQAMRSVKKETLKLLETFIEKSSDKQVIYSNFLQPLLEAVLGDYRTNIPETRDPEVLSLMTAIITSLKQL
SQ  VHPEVPKILEAVFETTLSMITKNFEDYPYHRINFFNLIRAINSNAFTVFHNLHPQQFKLLIDCVVWAFKHTERNISETGL
SQ  HILKELIENVSKNSDVANVFFKTYLVSLLNDILYILTDSFHKSGFALECDILRMMFQVVENGVVKIPLFDPQQANFPSNS
SQ  EYVKEIVVTFLSASPNVSRPQIQAFVTRLFNLANINNNDFKSATRDFLITLKEWKSHENADLYSDEKNIEKALALKKQSM
SQ  IPGMVRPNDVNLEMNDL
//