ID  Q557F4;
PN  Probable importin subunit alpha-A;
GN  DDB_G0273595;
OS  44689;
SL  Nucleus Position: SL-0178;
SL  Comments: Cytoplasm {ECO:0000250}. Nucleus envelope {ECO:0000250}.
DR  UNIPROT: Q557F4;
DR  UNIPROT: Q869V5;
DR  Pfam: PF00514;
DR  Pfam: PF16186;
DR  Pfam: PF01749;
DR  PROSITE: PS50176;
DR  PROSITE: PS51214;
DE  Function: Functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC). Binds specifically and directly to substrates containing either a simple or bipartite NLS motif (By similarity). {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005737;
GO  GO:0005635;
GO  GO:0005634;
GO  GO:0061608;
GO  GO:0008139;
GO  GO:0006607;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MSSRDKQDSRKKEFKKSLDSETARRKREENSIGIRKNAREELMLKRRGIVQPNPSTSYQIIVPPEVQEQFQKYENETMEN
SQ  KIKNLPGLVTALNSNDQAYVYSSLVQFRKLLSIHAYPPIDQVIECGIIPKLNQLLQCNNPKVQFESAWALTNIASGNNRQ
SQ  TQTVMESGSVPIFIQLLCAETTDEVKEQCAWALGNIAGDTVDSRNYLLKYGAMNALIPLLHYGEDNGATTTSANSERKIG
SQ  LIQNVVWTISNLCRGKPQPDFSVVSQCLPAINELIRIENLPSEIYGDLCWALSYLCDGPNTKIQAVIDSGVVPRLVKLLE
SQ  YPDSIVFTPALRAVGNIVTGESSQTQIVIDNNGVELITRLLAVQKKSIRKESCWALSNITAGEPSQIDVVVSNPKTVTTL
SQ  ISLLSHSEHDIKREACWALSNSTNNSSTKSIQTLVRHNILKHFIDLLNSQDLVILKIVLEGLINIIKEGEKTKTKTGVNP
SQ  YVNLISEMQGESIIYDLQEHQSKDVYKKAFELIEFFESSDYSDSENSEPNINQNGQYEFSSNYNSNSINI
//