ID  Q558Z2;
PN  Sun domain-containing protein 1;
GN  sun1;
OS  44689;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus membrane {ECO:0000269|PubMed:18266910, ECO:0000269|PubMed:19632001}; Single-pass membrane protein {ECO:0000269|PubMed:18266910, ECO:0000269|PubMed:19632001}; Nucleoplasmic side {ECO:0000269|PubMed:18266910, ECO:0000269|PubMed:19632001}.
DR  UNIPROT: Q558Z2;
DR  Pfam: PF07738;
DR  PROSITE: PS51469;
DE  Function: May have an important role in defining the spacing of the nuclear envelope lumen. Essential for centrosome attachment to the nucleus, maintenance of correct ploidy, proper mitosis, association of the centromere cluster with the centrosome and the maintenance of genome stability. Requires direct chromatin binding for inner nuclear membrane targeting. {ECO:0000269|PubMed:18266910, ECO:0000269|PubMed:19632001}.
DE  Reference Proteome: Yes;
GO  GO:0005639;
GO  GO:0005635;
GO  GO:0005637;
GO  GO:0005640;
GO  GO:0005654;
GO  GO:0003682;
GO  GO:0003677;
GO  GO:0042802;
GO  GO:0043495;
GO  GO:0051301;
GO  GO:0034508;
GO  GO:0007098;
GO  GO:0051642;
GO  GO:0000070;
GO  GO:0006998;
GO  GO:0006997;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MSGDYKPNYQSSPSRKRLPLQSKDQASIYKYQTPSTLNLYNNTVNNNSSNNSNNHLLHNSNPNSSYLYDSSKQYSNQINI
SQ  RNNSNSNSNTNNITSKKASSSYSINNKVDHNSHNNNDDDDIEDDVDINYSTNNASSNILHNRFSNSNKDDSYIDYSTDEN
SQ  PKILKQPQPLYNHLNNQIQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQRNNNNNSNSSNNNNTSTTIKRNNQQID
SQ  NNSNKNIISKFIGDPWKNFYYGSNKSLWPFERNNNSNNSSNNNNKVNFKQAIWIFIFSVLFIGCLLGLFSTNFYGIHIYF
SQ  PSFSTTKTNSPFNSTNNNIQFSNLITKEQLYPIIDEYFKKNEILKSYNKLFEKIENDIKYLSEREQYKDIINEIKEELKL
SQ  VKLSNMDEDRVNQLISKMINHYNNNENNKQELKELLSKSIEELTKLKSDSKEQLIQISTESMNQLGQLKSESINQLGQVK
SQ  SESIDKFQSTLKSLSKEEQSKIEREFNHQFNQLNKDADQLLSQHSLKIEKLREEINENQQSSLLKLTQEYKQLEERLKEF
SQ  SSKLQQSISSSSMDQFESWKLVFIKDIEERINKESSKLTNQYIQLTQQFTKIQSFIKDNPSIDSLTNTIESLEGIKLLIE
SQ  DILEVYSADKIAKVDYALGLAGASIEYNALHYRVSETYPPIKGSGSGSGSGGANGNSLGLYYYNLATNWIFPQPKPNPPE
SQ  TILDPMVNTGSCWGFYTGNGTIVIRLAKKIAITEVTMEHISSNISHHIDSAPKEFQVFGLINSSDIGQSLGVFTYDTTIN
SQ  RHLQTFKVNKIQSTTTTTTNQDQNDDDNIQEFSHVALRILSNHGYRYTCIYRFRVHGYQIPHPEQEQIQIIQEEQSFKQE
SQ  EINQQQIEQIEQIEQIEKQQQSDEL
//