ID  Q5F452;
PN  Myotubularin-related protein 8;
GN  MTMR8;
OS  9031;
SL  Nucleus Position: SL-0178;
SL  Comments: Nucleus envelope {ECO:0000250|UniProtKB:Q96EF0}.
DR  UNIPROT: Q5F452;
DR  Pfam: PF06602;
DR  PROSITE: PS51339;
DR  PROSITE: PS00383;
DE  Function: Phosphatase that acts on lipids with a phosphoinositol headgroup (By similarity). Has phosphatase activity towards phosphatidylinositol 3-phosphate and phosphatidylinositol 3,5- bisphosphate (By similarity). {ECO:0000250|UniProtKB:Q96EF0}.
DE  Reference Proteome: Yes;
GO  GO:0005635;
GO  GO:0052629;
GO  GO:0106018;
GO  GO:0004438;
GO  GO:0010507;
GO  GO:0046856;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MEHITTPKVENVKLLDRYTNRKAASGTLYLTATHLIYVDASAEVRKETWILHHHIATVEKLPLTTAGCPLLIHCKNFHVA
SQ  HFVIGQERDCHEVYTSLLKLSQPVKPEELYAFSYNPKMSKDNREIGWKLIDLKVDYQRMGIPNDYWEITDLNKDYEVCNT
SQ  YPPEIVVPRAASKATVIGSSRFRSRGRIPVLSYLYKENNAAICRCSQPLSGFSARCLEDEQMLQAIREANPGSPFMYVVD
SQ  TRPKLNAMANRAAGKGYENEDNYDNIRFKFIGIENIHVMRSSLQKLLEVCETKSPSMSDFLTGLENSGWLRHIKAVMDAS
SQ  VFLAKAVKDEKASVLVHCSDGWDRTAQVCSLASLLLDPFYRAFKGFMVLIEKEWIAMGHKFSHRCGHLDGDPKEVSPVFT
SQ  QFIECVWQLMQQFPCTFEFNEHFLLEIHDHVYSCQFGNFLGTCHKEREDLKIFEKTHSLWPFLLQKKQELRNPLYRGFTA
SQ  YKELQPNTLPFSFQFWCGMYNRFDKGMHPKQCVLDHLLSCMNQKIKLEDNASELENKLPFLDGPLPNEACFLSKVGCAAS
SQ  KTPMLNTPQDYEGEAPPVLTNGISVGDINVTSDVDQRNKENLANHRDLHLNDSVDVLNSEAKDGKPQHH
//