ID  Q5HZE2;
PN  Ion channel TACAN;
GN  Tmem120a;
OS  10116;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Cell membrane {ECO:0000250|UniProtKB:Q8C1E7}; Multi-pass membrane protein {ECO:0000255}. Nucleus inner membrane {ECO:0000250|UniProtKB:Q8C1E7}; Multi-pass membrane protein {ECO:0000255}.
DR  UNIPROT: Q5HZE2;
DR  Pfam: PF07851;
DE  Function: Ion channel involved in sensing mechanical pain. Contributes to mechanosensitive currents in nocireceptors and detecting mechanical pain stimuli. May also be required for efficient adipogenesis. {ECO:0000250|UniProtKB:Q8C1E7}.
DE  Reference Proteome: Yes;
GO  GO:0016021;
GO  GO:0016020;
GO  GO:0005637;
GO  GO:0005886;
GO  GO:0005216;
GO  GO:0050966;
GO  GO:0045444;
GO  GO:0034220;
GO  GO:0051291;
GO  GO:0051260;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MQSPPPDPLGDCLRNWEDLQQDFQGIQETHRLYRVKLEELTKLQDNCTNSITRQKKRLQELALVLKKCRPSLPSESLEAA
SQ  QELESQIKERQGLFFDMEAYLPKKNGLYLSLVLGNVNVTLLSKQAKFAYKDEYEKFKLYLTIILIVISFTCRFLLNSRVT
SQ  DAAFNFLLVWYYCTLTIRESILINNGSRIKGWWVFHHYVSTFLSGVMLTWPDGLMYQKFRNQFLSFSMYQSFVQFLQYYY
SQ  QSGCLYRLRALGERHTMDLTVEGFQSWMWRGLTFLLPFLFFGHFWQLFNALTLFNLARDPECKEWQVLMCGLPFLLLFLG
SQ  NFFTTLRVVHQKFHSQQHGSKKD
//