ID  Q62733;
PN  Lamina-associated polypeptide 2, isoform beta;
GN  Tmpo;
OS  10116;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0179;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus inner membrane; Single-pass type II membrane protein. Chromosome {ECO:0000250}. Note=Tightly associated with the nuclear lamina.
DR  UNIPROT: Q62733;
DR  Pfam: PF03020;
DR  Pfam: PF08198;
DR  PROSITE: PS50954;
DR  PROSITE: PS50955;
DE  Function: Binds directly to lamin B1 and chromosomes in a mitotic phosphorylation-regulated manner. May play an important role in nuclear envelope reassembly at the end of mitosis and/or anchoring of the nuclear lamina and interphase chromosomes to the nuclear envelope.
DE  Reference Proteome: Yes;
GO  GO:0000785;
GO  GO:0016021;
GO  GO:0005635;
GO  GO:0005637;
GO  GO:0005634;
GO  GO:0003677;
GO  GO:0042802;
GO  GO:0005521;
GO  GO:0031468;
GO  GO:0006355;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MPEFLEDPSVLTKDKLKSELVANNVTLPAGEQRKDVYVQLYLQHLTARNRPPLAAGANSKGPPDFSSDEEREPTPVLGSG
SQ  ASVGRGRGAVGRKATKKTDKPRPEDKDDLDVTELSNEELLEQLVRYGVNPGPIVGTTRKLYEKKLLKLREQGAESRSSTP
SQ  LPTVSSSAENTRQNGSNDSDRYSDNDEDSKIELKLEKREPLKGRAKTPVTLKQRRIEHNQSYSEAGVTETEWTSGSSKGG
SQ  PLQALTRESTRGSRRTPRRRVEPSQHFRVDGAVISESTPIAETIKASSNDSLVANRLTGNFKHASSILPITEFSDITRRT
SQ  PKKPLTRAEVGEKTEERRVERDILKEMFPYEASTPTGISASCRRPIKGAAGRPLELSDFRMEESFSSKYVPKYVPLADVK
SQ  SEKTKKGRSVPMWIKMLLFALVAGFLFLVYQAMETNQGNPFTNFLQDTKISN
//