ID  Q640W2;
PN  Twinfilin-2-B;
GN  twf2;
OS  8355;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasm, perinuclear region {ECO:0000250}. Note=Perinuclear and G-actin-rich cortical actin structure sublocalization. {ECO:0000250}.
DR  UNIPROT: Q640W2;
DR  Pfam: PF00241;
DR  PROSITE: PS51263;
DE  Function: Actin-binding protein involved in motile and morphological processes. Inhibits actin polymerization, likely by sequestering G- actin (By similarity). {ECO:0000250}.
DE  Reference Proteome: Yes;
GO  GO:0005856;
GO  GO:0048471;
GO  GO:0003779;
GO  GO:0030837;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MAHQTGIHATPELKEFFAKARNGSVRLIKVIIEEEQLVLGSHKELKHAWDQDYDAFVLQLLDESQPCYILYRLDSQNAQG
SQ  YEWIFLSWSPDHSPVRLKMLYAATRATVKKEFGGGHIKDEIFGTLKEDVALSGYKKHVSSCAAPAPLTAAERELQAIKIN
SQ  EVKTEISVESKQQTLQGLSFPLRPQAEEAILLLKQKKINYIQLRLDLEKETVDLVHTKHTEIQDLPGRIPQDTARYHFFL
SQ  YKHSHEGDHLESVVFIYSMPGYKCSIKERMLYSSCKNRLLDSVEQDFLMEIAKKIEIEDGAELTDEFLYDEVHPKQHAFK
SQ  QAFAKPKGPAGKRGQKRLIKGPGENGEDS
//