ID Q65179; PN p8; GN CP530R; OS 10498; SL Nucleus Position: SL-0382; SL Comments: [Polyprotein pp62]: Host cytoplasm, host perinuclear region {ECO:0000269|PubMed:9223468}. Note=Found in perinuclear cytoplasmic viral factories during assembly. {ECO:0000269|PubMed:9223468}. [p35]: Virion {ECO:0000269|PubMed:30185597, ECO:0000269|PubMed:33629764}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {ECO:0000269|PubMed:33629764}. [p15]: Virion {ECO:0000269|PubMed:30185597, ECO:0000269|PubMed:33629764}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {ECO:0000269|PubMed:33629764}. [p8]: Virion {ECO:0000269|PubMed:30185597}. Note=Located in the core shell, which functions like a matrix between the DNA and the inner envelope. {ECO:0000303|PubMed:30185597}. DR UNIPROT: Q65179; DR UNIPROT: Q86851; DR PDB: 6LNL; DR PDB: 6NLN; DR PDB: 7BQ9; DR PDB: 7BQA; DR PDB: 7CP2; DE Function: [Polyprotein pp62]: Essential for the correct assembly and maturation of the core of the virion. {ECO:0000269|PubMed:19846532}. [p35]: Component of the core shell (PubMed:30185597). Binds to phosphatidylserine, which may enable the core shell binding with the inner membrane (PubMed:32519301). {ECO:0000269|PubMed:30185597, ECO:0000269|PubMed:32519301}. [p15]: Component of the core shell (PubMed:30185597). Binds to phosphatidylserine and DNA, which may link the core shell to the inner membrane and to the viral nucleoid (PubMed:32451720). {ECO:0000269|PubMed:30185597, ECO:0000269|PubMed:32451720}. [p8]: Component of the core shell. {ECO:0000269|PubMed:30185597}. DE Reference Proteome: Yes; GO GO:0044220; GO GO:0044423; GO GO:0019069; TP Membrane Topology: Unknown; Source: UniProt - Sequence Analysis; SQ MPSNMKQFCKISVWLQQHDPDLLEIINNLCMLGNLSAAKYKHGVTFIYPKQAKIRDEIKKHAYSNDPSQAIKTLESLILP SQ FYIPTPAEFTGEIGSYTGVKLEVEKTEANKVILKNGEAVLVPAADFKPFPDRRLAVWIMESGSMPLEGPPYKRKKEGGGN SQ DPPVPKHISPYTPRTRIAIEVEKAFDDCMRQNWCSVNNPYLAKSVSLLSFLSLNHPTEFIKVLPLIDFDPLVTFYLLLEP SQ YKTHGDDFLIPETILFGPTGWNGTDLYQSAMLEFKKFFTQITRQTFMDIADSATKEVDVPICYSDPETVHSYTNHVRTEI SQ LHHNAVNKVTTPNLVVQAYNELEQTNTIRHYGPIFPESTINALRFWKKLWQDEQRFVIHGLHRTLMDQPTYETSEFAEIV SQ RNLRFSRPGNNYINELNITSPAMYGDKHTTGDIAPNDRFAMLVAFINSTDFLYTAIPEEKVGGNETQTSSLTDLVPTRLH SQ SFLNHNLSKLKILNRAQQTVRNILSNDCLNQLKHYVKHTGKNEILKLLQE //