ID  Q683C9;
PN  Serine/threonine-protein kinase Aurora-2;
GN  AUR2;
OS  3702;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Nucleus membrane. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Nuclear membrane in interphase cells, spindle poles at prophase and mitotic spindle from metaphase to telophase.
DR  UNIPROT: Q683C9;
DR  UNIPROT: O82309;
DR  Pfam: PF00069;
DR  PROSITE: PS00107;
DR  PROSITE: PS50011;
DR  PROSITE: PS00108;
DE  Function: Phosphorylates specifically 'Ser-10' of histone H3 in vitro. Associates with cytoskeletal structures that are necessary for cytokinesis and with the microtubule spindle. Might colocalize with gamma-tubulin and function in microtubule organizing centers (MTOCs). {ECO:0000269|PubMed:16028112}.
DE  Reference Proteome: Yes;
DE  Interaction: O23160; IntAct: EBI-25517190; Score: 0.56
DE  Interaction: Q9SSA8; IntAct: EBI-25519383; Score: 0.56
GO  GO:0032133;
GO  GO:0005737;
GO  GO:0031965;
GO  GO:0005634;
GO  GO:0005876;
GO  GO:0051233;
GO  GO:0000922;
GO  GO:0005524;
GO  GO:0035175;
GO  GO:0035174;
GO  GO:0106310;
GO  GO:0007052;
GO  GO:0006468;
GO  GO:0032465;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MLYQAASEAAQKRWTTSDFDIGKPLGRGKFGHVYLAREKRSDHIVALKVLFKAQLQQSQVEHQLRREVEIQSHLRHPNIL
SQ  RLYGYFYDQKRVYLILEYAVRGELYKELQKCKYFSERRAATYVASLARALIYCHGKHVIHRDIKPENLLIGAQGELKIAD
SQ  FGWSVHTFNRRRTMCGTLDYLPPEMVESVEHDASVDIWSLGILCYEFLYGVPPFEAREHSETYKRIVQVDLKFPPKPIVS
SQ  SSAKDLISQMLVKESTQRLALHKLLEHPWIVQNADPSGLYRG
//