ID  Q684P5;
PN  Rap1 GTPase-activating protein 2;
GN  RAP1GAP2;
OS  9606;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000269|PubMed:15632203}. Cytoplasm, perinuclear region {ECO:0000269|PubMed:15632203}.
DR  UNIPROT: Q684P5;
DR  UNIPROT: B2RTY5;
DR  UNIPROT: Q684P4;
DR  UNIPROT: Q6AI00;
DR  UNIPROT: Q6ZVF0;
DR  UNIPROT: Q9UPW2;
DR  Pfam: PF02145;
DR  PROSITE: PS50085;
DR  OMIM: 618714;
DR  DisGeNET: 23108;
DE  Function: GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP- bound state. {ECO:0000269|PubMed:15632203}.
DE  Reference Proteome: Yes;
DE  Interaction: P62258; IntAct: EBI-3452989; Score: 0.00
DE  Interaction: Q9H4A3; IntAct: EBI-3454034; Score: 0.00
DE  Interaction: Q6P5F9; IntAct: EBI-11603310; Score: 0.35
DE  Interaction: Q6FHY5; IntAct: EBI-24366985; Score: 0.56
GO  GO:0005813;
GO  GO:0005737;
GO  GO:0005829;
GO  GO:0031965;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0005096;
GO  GO:0090630;
GO  GO:0002250;
GO  GO:0008361;
GO  GO:0051056;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MFGRKRSVSFGGFGWIDKTMLASLKVKKQELANSSDATLPDRPLSPPLTAPPTMKSSEFFEMLEKMQGIKLEEQKPGPQK
SQ  NKDDYIPYPSIDEVVEKGGPYPQVILPQFGGYWIEDPENVGTPTSLGSSICEEEEEDNLSPNTFGYKLECKGEARAYRRH
SQ  FLGKDHLNFYCTGSSLGNLILSVKCEEAEGIEYLRVILRSKLKTVHERIPLAGLSKLPSVPQIAKAFCDDAVGLRFNPVL
SQ  YPKASQMIVSYDEHEVNNTFKFGVIYQKARQTLEEELFGNNEESPAFKEFLDLLGDTITLQDFKGFRGGLDVTHGQTGVE
SQ  SVYTTFRDREIMFHVSTKLPFTDGDAQQLQRKRHIGNDIVAIIFQEENTPFVPDMIASNFLHAYIVVQVETPGTETPSYK
SQ  VSVTAREDVPTFGPPLPSPPVFQKGPEFREFLLTKLTNAENACCKSDKFAKLEDRTRAALLDNLHDELHAHTQAMLGLGP
SQ  EEDKFENGGHGGFLESFKRAIRVRSHSMETMVGGQKKSHSGGIPGSLSGGISHNSMEVTKTTFSPPVVAATVKNQSRSPI
SQ  KRRSGLFPRLHTGSEGQGDSRARCDSTSSTPKTPDGGHSSQEIKSETSSNPSSPEICPNKEKPFMKLKENGRAISRSSSS
SQ  TSSVSSTAGEGEAMEEGDSGGSQPSTTSPFKQEVFVYSPSPSSESPSLGAAATPIIMSRSPTDAKSRNSPRSNLKFRFDK
SQ  LSHASSGAGH
//