ID  Q6AXM5;
PN  Choline/ethanolaminephosphotransferase 1;
GN  Cept1;
OS  10116;
SL  Nucleus Position: SL-0178;
SL  Nucleus Position: SL-0182;
SL  Comments: Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q9Y6K0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y6K0}. Nucleus membrane {ECO:0000250|UniProtKB:Q9Y6K0}; Multi-pass membrane protein {ECO:0000250|UniProtKB:Q9Y6K0}.
DR  UNIPROT: Q6AXM5;
DR  Pfam: PF01066;
DR  PROSITE: PS00379;
DE  Function: Catalyzes both phosphatidylcholine and phosphatidylethanolamine biosynthesis from CDP-choline and CDP- ethanolamine, respectively. Involved in protein-dependent process of phospholipid transport to distribute phosphatidyl choline to the lumenal surface. Has a higher cholinephosphotransferase activity than ethanolaminephosphotransferase activity. {ECO:0000250|UniProtKB:Q9Y6K0}.
DE  Reference Proteome: Yes;
GO  GO:0005789;
GO  GO:0005794;
GO  GO:0016021;
GO  GO:0031965;
GO  GO:0047359;
GO  GO:0004142;
GO  GO:0004307;
GO  GO:0046872;
GO  GO:0016780;
GO  GO:0006656;
GO  GO:0006646;
TP  Membrane Topology: Transmembrane; Source: UniProt - Sequence Analysis {ECO:0000255};
SQ  MSGHRSTRKRCGDSHPESPVGFGHMSTTGCILNKLFQLPTPPLSRHQLKRLEEHRYQSAGRSLLEPLMQGYWEWLVGRVP
SQ  SWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYIACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSL
SQ  STVFVVLGTCIAVQLGTNPDWMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIP
SQ  VLNIQMKLFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLAVMIYKKSAVQLFEKHPCLYI
SQ  LTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLDQYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLH
SQ  IHVFRIKTSTAHSNHH
//