ID  Q6AXS5;
PN  Plasminogen activator inhibitor 1 RNA-binding protein;
GN  Serbp1;
OS  10116;
SL  Nucleus Position: SL-0198;
SL  Comments: Cytoplasm {ECO:0000250|UniProtKB:Q8NC51}. Nucleus {ECO:0000250|UniProtKB:Q8NC51}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8NC51}.
DR  UNIPROT: Q6AXS5;
DR  UNIPROT: Q8VHU3;
DR  Pfam: PF04774;
DR  Pfam: PF16174;
DE  Function: May play a role in the regulation of mRNA stability. Binds to the 3'-most 134 nt of the SERPINE1/PAI1 mRNA, a region which confers cyclic nucleotide regulation of message decay. Seems to play a role in PML-nuclear bodies formation. {ECO:0000250|UniProtKB:Q8NC51}.
DE  Reference Proteome: Yes;
DE  Interaction: P61980; IntAct: EBI-931202; Score: 0.35
DE  Interaction: Q62976; IntAct: EBI-1638145; Score: 0.35
DE  Interaction: P35968; IntAct: EBI-22252438; Score: 0.35
DE  Interaction: P43403; IntAct: EBI-22252989; Score: 0.35
DE  Interaction: P11274; IntAct: EBI-22253187; Score: 0.35
DE  Interaction: P08575; IntAct: EBI-22253598; Score: 0.35
DE  Interaction: P51692; IntAct: EBI-22257101; Score: 0.35
DE  Interaction: Q96RT1; IntAct: EBI-22258042; Score: 0.35
DE  Interaction: O75096; IntAct: EBI-22258804; Score: 0.35
GO  GO:0005737;
GO  GO:0005634;
GO  GO:0048471;
GO  GO:0005886;
GO  GO:0003730;
GO  GO:0043022;
GO  GO:0003723;
GO  GO:0032183;
GO  GO:0030578;
GO  GO:0042981;
TP  Membrane Topology: Unknown; Source: UniProt - Sequence Analysis;
SQ  MPGHLQEGFGCVVTNRFDQLFDDESDPFEVLKAAENKKKEAGGGGVGGPGAKSAAQAAAQTNSNAAGKQLRKESQKDRKN
SQ  PLPPSVGVADKKEETQPPVALKKEGIRRVGRRPDQQLQGDGKIIDRRPERRPPRERRFEKPLEEKGEGGEFSVDRPIIER
SQ  PIRGRGGLGRGRGGRGRGMGRGDGFDSRGKREFDRHSGSDRSSFSHYSGLKHEDKRGGSGSHNWGTVKDELTESPKYIQK
SQ  QISYNCSDLEQSNVTEETPEGEEHPVADTENKENEVEEVKEEGPKEMTLDEWKAIQNKDRAKVEFNIRKPNEGADGQWKK
SQ  GFVLHKSKSEEAHAEDSVMDHHFRKPANDITSQLEINFGDLGRPGRGGRGGRGGRGRGGRPNRGSRTDKSSASAPDVDDP
SQ  EAFPALA
//